• Log in with Facebook Log in with Twitter Log In with Google      Sign In    
  • Create Account
              Advocacy & Research for Unlimited Lifespans


Supraphysiological levels of GDF11 induce striated muscle atrophy


  • Please log in to reply
1 reply to this topic
⌛⇒ MITOMOUSE has been fully funded!

#1 alc

  • Validating
  • 208 posts
  • 101
  • Location:Columbus, OH
  • NO

Posted 11 March 2017 - 09:29 PM

" Supraphysiological levels of GDF11 induce striated muscle atrophy"




"These data indicate that bioactive GDF11 at supraphysiological levels cause wasting of both skeletal and cardiac muscle.

Rather than a therapeutic agent, GDF11 should be viewed as a potential deleterious biomarker in muscle wasting diseases."

#2 DareDevil

  • Guest
  • 282 posts
  • 81
  • Location:Vermont

Posted 18 March 2017 - 03:06 PM

Possibly, but while this might be true, can anyone here assess at what limit the studied "supraphysiological levels" that are dangerous for atrophy occur? For example, Paracetamol can be deadly at certain "supraphysiological levels" but the FDA authorizes its over the counter sale. Such a vague term doesn't instruct us as to the dosage levels of GDF-11 at which we must exercise care. TIA.



Click HERE to rent this BIOSCIENCE adspot to support LongeCity (this will replace the google ad above).

Also tagged with one or more of these keywords: gdf11

0 user(s) are reading this topic

0 members, 0 guests, 0 anonymous users