• Log in with Facebook Log in with Twitter Log In with Google      Sign In    
  • Create Account
  LongeCity
              Advocacy & Research for Unlimited Lifespans

Photo
- - - - -

Basis users should stop taking it

pterostilbene

  • This topic is locked This topic is locked
27 replies to this topic

#1 MikeDC

  • Guest
  • 1,570 posts
  • -457
  • Location:Virginia

Posted 26 July 2017 - 01:36 PM


Pterostilbene increases LDL and Triglycerides. It is junk.
So dump basis and take Pure Niagen.

https://www.ncbi.nlm...les/PMC4099343/
  • Enjoying the show x 1
  • Disagree x 1

#2 Supierce

  • Guest
  • 94 posts
  • 28
  • Location:Vermont

Posted 26 July 2017 - 02:42 PM

Talk about cherry-picking your studies! Here - try this link instead:

 

https://scholar.goog...t=1,46&as_vis=1

 



#3 MikeDC

  • Topic Starter
  • Guest
  • 1,570 posts
  • -457
  • Location:Virginia

Posted 26 July 2017 - 02:53 PM

There is only one clinical trial completed and it showed pterostilbene is bad for metabolism. Maybe it will help with cancer. Someone needs to start a trial.

https://clinicaltria...&state1=&recrs=

Edited by MikeDC, 26 July 2017 - 02:54 PM.

  • Ill informed x 1
  • Informative x 1

#4 able

  • Guest
  • 851 posts
  • 406
  • Location:austin texas
  • NO

Posted 26 July 2017 - 04:59 PM

It raised LDL somewhat.  

 

It lowered blood pressure by a significant amount.  

 

Don't think it's really fair to say it is "junk", and "bad for metabolism" based on that.


  • Agree x 1

#5 MikeDC

  • Topic Starter
  • Guest
  • 1,570 posts
  • -457
  • Location:Virginia

Posted 26 July 2017 - 05:06 PM

It raised blood pressure for normal people and lowered for people with high blood pressure. They choose not to report triglycerides change in the paper. You can read the data from the clinical trials page.
  • Ill informed x 1
  • Informative x 1

#6 Asor

  • Guest
  • 65 posts
  • 12
  • Location:Italy
  • NO

Posted 27 July 2017 - 03:56 PM

im not even convinced that LDL is reallly "bad", the cholesterol thing is way more complicated than the way we've been told for years.

 

 



#7 MikeDC

  • Topic Starter
  • Guest
  • 1,570 posts
  • -457
  • Location:Virginia

Posted 27 July 2017 - 04:19 PM

LDL is not bad. It is necessary for life. Higher than normal levels means your metabolic state is not in perfect condition. High triglycerides generally result from eating too much carbohydrates and considered bad. When you see both increasing without change in eating, it means your body is not functioning as good as before.

#8 MikeDC

  • Topic Starter
  • Guest
  • 1,570 posts
  • -457
  • Location:Virginia

Posted 27 July 2017 - 04:28 PM

The range of triglycerides is much higher compared to placebo. Who want to see his triglycerides goes higher by a few hundreds points? Scary!

Attached Files


  • Ill informed x 1

#9 tintinet

  • Guest
  • 1,972 posts
  • 503
  • Location:ME

Posted 27 July 2017 - 04:36 PM

Been taking over 600 mg pterostilbene/day for years. Recent labs: triglicerides 55 mg/dl, ldl 43 mg/dl, hdl 74 mg/dl.
  • Agree x 2
  • Informative x 1

#10 MikeDC

  • Topic Starter
  • Guest
  • 1,570 posts
  • -457
  • Location:Virginia

Posted 27 July 2017 - 05:35 PM

Your LDL is too low. Hormones are made from LDL.
  • Enjoying the show x 1

#11 Benko

  • Guest
  • 221 posts
  • 328
  • Location:US

Posted 27 July 2017 - 09:16 PM

Been taking over 600 mg pterostilbene/day for years. Recent labs: triglicerides 55 mg/dl, ldl 43 mg/dl, hdl 74 mg/dl.

 

Can I ask why you are taking that much?  Did the pterostilbene and whatever else you are taking produce significant changes in your lipids?

 

Were you taking lots of resveratrol?

 

Thanks.



#12 tintinet

  • Guest
  • 1,972 posts
  • 503
  • Location:ME

Posted 28 July 2017 - 11:19 PM

I used to take a lot  of resveratrol.  Thought pterostilbene might be better. Hasn't changed my lipid profile at all. Been like this for decades.

 

 

Been taking over 600 mg pterostilbene/day for years. Recent labs: triglicerides 55 mg/dl, ldl 43 mg/dl, hdl 74 mg/dl.

 

Can I ask why you are taking that much?  Did the pterostilbene and whatever else you are taking produce significant changes in your lipids?

 

Were you taking lots of resveratrol?

 

Thanks.

 

 


  • Agree x 2
  • Informative x 1

#13 MikeDC

  • Topic Starter
  • Guest
  • 1,570 posts
  • -457
  • Location:Virginia

Posted 30 July 2017 - 10:22 AM

Elysium is shipping basis that is pure white. Niagen is brown as Nicotinamide Riboside chloo salt. So what is in basis is no longer Niagen.

For what it is worth, here is another exert from the note from Elysium: "While the specific Basis formulation and the amount of each ingredient have not changed, this new production process has allowed us to take an exceptional product and make it even purer. We also have eliminated color variations and can now provide a consistently white final product, as you may have seen with your most recent shipment. This reflects our ongoing commitment to being a trusted source for our customers by continually exceeding the highest standards in the industry."
  • Enjoying the show x 1
  • Pointless, Timewasting x 1

#14 bluemoon

  • Guest
  • 761 posts
  • 94
  • Location:south side
  • NO

Posted 30 July 2017 - 10:33 AM

Elysium is shipping basis that is pure white. Niagen is brown as Nicotinamide Riboside chloo salt. So what is in basis is no longer Niagen. 

 

Elysium still uses NR as their website indicates.



#15 MikeDC

  • Topic Starter
  • Guest
  • 1,570 posts
  • -457
  • Location:Virginia

Posted 30 July 2017 - 10:55 AM

It is Nicotinamide Riboside alright. But pure NR is not stable and is not effective. Niagen is NR chloride.
  • Needs references x 2
  • Informative x 1

#16 bluemoon

  • Guest
  • 761 posts
  • 94
  • Location:south side
  • NO

Posted 30 July 2017 - 12:48 PM

It is Nicotinamide Riboside alright. But pure NR is not stable and is not effective. Niagen is NR chloride.

 

Evidence that Elysium's NR is ineffective?

 

If Elysium is no longer tied to ChromaDex then great news.

 

ChromaDex's CEO made that strange statement at the last share holder meeting: They are getting Niagen off the market by letting it run out and maybe even buying some back so that they are the sole provider - or maybe not as they may let a few vendors sell it. Chromadex definitely has a great strategy. Perhaps.



#17 MikeDC

  • Topic Starter
  • Guest
  • 1,570 posts
  • -457
  • Location:Virginia

Posted 30 July 2017 - 01:55 PM

Nicotinamide Riboside Chloride was intentionally made to stabilize NR so it can be absorbed without breaking down. If you read the patents, you should be able to find the reason why chloride was added. All studies so far have used Niagen. So NR without Chloride is unproven. Elysium can't use Niagen for their clinical trials and then sell pure NR. That is fraud. They need to do another trial with pure NR to prove it is still effective.
  • Needs references x 1
  • Pointless, Timewasting x 1
  • Ill informed x 1
  • Good Point x 1
  • Informative x 1

#18 MikeDC

  • Topic Starter
  • Guest
  • 1,570 posts
  • -457
  • Location:Virginia

Posted 31 July 2017 - 02:58 PM

Looks like Elysium is using counterfeit Chinese NR in the new Basis. The following was posted on yahoo CDXC conversations.
Time to cancel Basis subscription.

"So I am looking at the new BASIS plastic jar here this morning, which belongs to a friend of mine who has an annual subscription with Elysium Health. The ChromaDex patent numbers are not listed on the side of the jar anymore. Inside the jar are white capsules, instead of light tan colored capsules. The jar doesn't say "Made in USA", or have an FDA approval logo."
  • Disagree x 1

#19 able

  • Guest
  • 851 posts
  • 406
  • Location:austin texas
  • NO

Posted 31 July 2017 - 03:07 PM

Good point.  Seems they believe the Chromadex patent won't hold up, and are making their own, or buying elsewhere.

 

Maybe from chinese supplier?  But not sure it's fair to call it "counterfeit".  They are not claiming it is Niagen, or something that it is not.



#20 msearch444

  • Guest
  • 3 posts
  • 0
  • Location:Atlanta, GA

Posted 31 July 2017 - 03:15 PM

Been taking over 600 mg pterostilbene/day for years. Recent labs: triglicerides 55 mg/dl, ldl 43 mg/dl, hdl 74 mg/dl.

 

 

Wow!!! That is a ton of P'tero!  i do 150mg per day for years and i was about to say my Cholesterol readings are amazeballs - 

 

Couple of questions:

 - Where do you get your p'tero and where did you come up with 600 mg being an ideal dose? (sorry sort of a newbie to the board)


  • like x 1

#21 tintinet

  • Guest
  • 1,972 posts
  • 503
  • Location:ME

Posted 01 August 2017 - 12:32 PM

Been taking over 600 mg pterostilbene/day for years. Recent labs: triglicerides 55 mg/dl, ldl 43 mg/dl, hdl 74 mg/dl.



Wow!!! That is a ton of P'tero! i do 150mg per day for years and i was about to say my Cholesterol readings are amazeballs -

Couple of questions:
- Where do you get your p'tero and where did you come up with 600 mg being an ideal dose? (sorry sort of a newbie to the board)

Get my pterostilbene from various sources. Sometimes from Amazon, if pricing is decent. Took 600 mg rather by accident. It's likely serious overkill - I have no idea what an optimal dose might be.

#22 MikeDC

  • Topic Starter
  • Guest
  • 1,570 posts
  • -457
  • Location:Virginia

Posted 01 August 2017 - 12:43 PM

Been taking over 600 mg pterostilbene/day for years. Recent labs: triglicerides 55 mg/dl, ldl 43 mg/dl, hdl 74 mg/dl.


Wow!!! That is a ton of P'tero! i do 150mg per day for years and i was about to say my Cholesterol readings are amazeballs -

Couple of questions:
- Where do you get your p'tero and where did you come up with 600 mg being an ideal dose? (sorry sort of a newbie to the board)
Get my pterostilbene from various sources. Sometimes from Amazon, if pricing is decent. Took 600 mg rather by accident. It's likely serious overkill - I have no idea what an optimal dose might be.

I am sorry to say it. But your triglycerides and LDL are not normal. Are you eating organic grass?
  • Needs references x 1
  • Pointless, Timewasting x 1
  • Ill informed x 1

#23 Michael

  • Advisor, Moderator
  • 1,293 posts
  • 1,792
  • Location:Location Location

Posted 01 August 2017 - 04:01 PM

Talk about cherry-picking your studies! Here - try this link instead:

 

https://scholar.goog...t=1,46&as_vis=1

One can't respond to the selective picking of cherries by taking the entire year's fruit crop and dumping it on people's heads. Do you have any specific studies that would refute the specific finding of Mike's specific study?


  • Good Point x 1

#24 Michael

  • Advisor, Moderator
  • 1,293 posts
  • 1,792
  • Location:Location Location

Posted 01 August 2017 - 04:07 PM

Nicotinamide Riboside Chloride was intentionally made to stabilize NR so it can be absorbed without breaking down.


No, it was not. It was made because pure NR is extremely hygroscopic and would degrade in the capsule.

 

If you read the patents, you should be able to find the reason why chloride was added.


Indeed you can — so maybe you should read them before making claims about their contents.

 

All studies so far have used Niagen. So NR without Chloride is unproven. Elysium can't use Niagen for their clinical trials and then sell pure NR. That is fraud. They need to do another trial with pure NR to prove it is still effective.


There is no basis for this claim in biomedical science. NR is a defined molecule, not a botanical, and this is biochemistry, not celebrity collectibles. If the salt is soluble, it will behave in exactly the same way.


  • Agree x 2
  • WellResearched x 1

#25 Michael

  • Advisor, Moderator
  • 1,293 posts
  • 1,792
  • Location:Location Location

Posted 01 August 2017 - 04:16 PM

 

Been taking over 600 mg pterostilbene/day for years. Recent labs: triglicerides 55 mg/dl, ldl 43 mg/dl, hdl 74 mg/dl.

I am sorry to say it. But your triglycerides and LDL are not normal. Are you eating organic grass?

They're only not "normal" in the sense that it's "normal" to have a lousy lipid profile. "Goal LDL (to prevent atherosclerotic plaque formation) is between 50-70 mg/dL." — levels which are normal in hunter-gatherers — and TG of 40-60 is perfectly normal in people on CR or ketogenic diets.


  • Informative x 2
  • Agree x 1

#26 tintinet

  • Guest
  • 1,972 posts
  • 503
  • Location:ME

Posted 03 August 2017 - 02:10 PM

Been taking over 600 mg pterostilbene/day for years. Recent labs: triglicerides 55 mg/dl, ldl 43 mg/dl, hdl 74 mg/dl.

I am sorry to say it. But your triglycerides and LDL are not normal. Are you eating organic grass?

They're only not "normal" in the sense that it's "normal" to have a lousy lipid profile. "Goal LDL (to prevent atherosclerotic plaque formation) is between 50-70 mg/dL." — levels which are normal in hunter-gatherers — and TG of 40-60 is perfectly normal in people on CR or ketogenic diets.

My lipid profile has been pretty consistent for many years, as has my diet (aimed at CR and ketogenisis, although it strays off course from time to time.)

#27 MikeDC

  • Topic Starter
  • Guest
  • 1,570 posts
  • -457
  • Location:Virginia

Posted 03 August 2017 - 03:13 PM

LDL causes atherosclerotic plauge is still debatable. Recent studies seems to indicate low NAD+ and Sirtuins and inflammation are the real cause
  • Needs references x 5

#28 MikeDC

  • Topic Starter
  • Guest
  • 1,570 posts
  • -457
  • Location:Virginia

Posted 03 August 2017 - 03:22 PM

https://www.ncbi.nlm...ic plaque sirt1
  • Enjoying the show x 2





Also tagged with one or more of these keywords: pterostilbene

1 user(s) are reading this topic

0 members, 1 guests, 0 anonymous users