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The price of NR and Metformin

chromadex metformin tru niagen

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39 replies to this topic

#31 Daniel Cooper

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Posted 18 September 2017 - 04:02 PM

If you believe that you should back up the truck and buy all the shares you can afford and then some.

 

I keep wondering my we've only got one human study released that really only shows the plasma levels achieved and not health benefits (unless something has been published I'm not aware of).  We are after all about 10 years into serious NR research (the Chromadex patents were initially filed in 2006 I believe).

 

I sincerely hope that NR is all you believe it to be,   We'll all be better off physically and you'll be better off financially.

 

 

 

 

 


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#32 MikeDC

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Posted 18 September 2017 - 04:17 PM

The first clinical trial that report on the health benefit of Niagen from Colorado trial is in the process of being published. Company can't release the results until it is published. Li Ka-Shing already saw the results before he invested. You can bet the result is good. My own experience and other friends' experience tells me NR is a miracle drug in improving health. I don't need the clinical trials to show me. It is a done deal. I am also sure that NR will be a drug. So people who think it is not effective since it is a supplement now, may find out it is too expensive to take when it is proven in clinical trials.
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#33 midas

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Posted 20 September 2017 - 02:00 PM

"Patients treated with a drug (Metformin) widely prescribed for type 2 diabetes can live longer than people without the condition, a large-scale study involving over 180,000 people has shown."

 

https://www.scienced...40807215552.htm


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#34 APBT

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Posted 20 September 2017 - 08:02 PM

"Patients treated with a drug (Metformin) widely prescribed for type 2 diabetes can live longer than people without the condition, a large-scale study involving over 180,000 people has shown."

 

https://www.scienced...40807215552.htm

 

FULL TEXT:  

Attached Files


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#35 MikeDC

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Posted 20 September 2017 - 08:42 PM

I remember reading one of the threads here that said the study was flawed due to the criteria they used to pick candidates. It was not a double blinded clinical trial. Just some statistics with arbitrary selection criteria. My mother was in metformin most her life and it didn't help her to get rid of the diabetes. It definitely didn't get her any younger. NAD+ precursors like NR is the right way to deal with aging. It deal with critical internal dificiencies. Senolytics is promising too. NAD+ precursors and Senolytics could form the one two punch to deal with aging.
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#36 midas

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Posted 21 September 2017 - 12:38 PM

I remember reading one of the threads here that said the study was flawed due to the criteria they used to pick candidates. It was not a double blinded clinical trial. Just some statistics with arbitrary selection criteria. My mother was in metformin most her life and it didn't help her to get rid of the diabetes. It definitely didn't get her any younger. NAD+ precursors like NR is the right way to deal with aging. It deal with critical internal dificiencies. Senolytics is promising too. NAD+ precursors and Senolytics could form the one two punch to deal with aging.

 

"large-scale study involving over 180,000 people"


Edited by midas, 21 September 2017 - 12:39 PM.

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#37 MikeDC

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Posted 21 September 2017 - 12:54 PM

It is not a clinical study. It is a statistical analysis. They get to pick who are included in the analysis.
"We used retrospective observational data from the UK Clinical Practice Research Datalink (CPRD) from 2000. Subjects with type 2 diabetes who progressed to first-line treatment with metformin or sulphonylurea monotherapy were selected and matched to people without diabetes. Progression to all-cause mortality was compared using parametric survival models that included a range of relevant co-variables."
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#38 midas

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Posted 21 September 2017 - 01:40 PM

Oh OK, in that case I'll ignore everyone else that does this sort of thing fro a living and just listen to you then......!

 

Virtually everything you have posted on the forum is disliked by most people that respond to it...WTF dude, what is your problem?


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#39 Harkijn

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Posted 21 September 2017 - 02:36 PM

This thread is made useless by MikeDC's hostile attitude. As I mentioned in another thread this is no way to promote NR, on the contrary.

 

However, since some people take metformin and others here are considering starting it, I would like to point to a possible downside: the relation between metformin and vitamin B12 deficiency:

https://www.endocrin...-b12-deficiency

The problem is that many people with low B!2 absorption do not know about their condition.


Edited by Harkijn, 21 September 2017 - 02:36 PM.

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#40 Michael

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Posted 22 September 2017 - 05:31 PM


 

Metformin is useless for anti aging.

 Metformin has already shown life extention

 
Metformin has been shown not to extend life every time it's been tested in otherwise-healthy, nonmutant, nonobese, nondiabetic, non-toxin-administered mice and rats.
 

"Patients treated with a drug (Metformin) widely prescribed for type 2 diabetes can live longer than people without the condition, a large-scale study involving over 180,000 people has shown."
 
https://www.scienced...40807215552.htm


MikeDC is right, for once: that metformin study is flawed.
 

You can't really use metformin anyway for a normal person, you will experience low blood sugar and faint.

This, on the other hand, is not true: metformin works primarily by improving hepatic insulin sensitivity, not by "forcing" glucose uptake or excretion; the risks of hypoglycemia from metformin alone are next to nil.


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