• Log in with Facebook Log in with Twitter Log In with Google      Sign In    
  • Create Account
  LongeCity
              Advocacy & Research for Unlimited Lifespans

Photo
- - - - -

Improving LIBIDO & ERECTION while on SSRI (Effexor)

ssri libido erection supplement sex sexual

  • Please log in to reply
16 replies to this topic
⌛⇒ MITOMOUSE has been fully funded!

#1 Forever21

  • Guest
  • 1,899 posts
  • 126

Posted 28 September 2017 - 04:38 PM


I'm looking the following:

 

https://examine.com/topics/Libido/

 

https://examine.com/topics/erections/

 

Curious as to what are safe and effective to use with SSRI if you want to improve libido and erection.


  • Informative x 1

#2 Rocket

  • Guest
  • 872 posts
  • 113
  • Location:Usa
  • NO

Posted 29 September 2017 - 01:10 AM

I might really consider if you need to be on a ssri if you're having these side effects. They can become permanent. The reason why no one has replied to your question is because no one knows how to reverse ssri induced ED.

Otherwise you are left with viagara and those types of medications for ED.

For libido, I don't think there is a anything out there legal that boost libido and desire for sex. Some anabolic drugs increase libido... That's about the only thing that is a sure libido booster.

Edited by Rocket, 29 September 2017 - 01:14 AM.

  • Agree x 1

#3 Forever21

  • Topic Starter
  • Guest
  • 1,899 posts
  • 126

Posted 29 September 2017 - 03:29 PM

I might really consider if you need to be on a ssri if you're having these side effects. They can become permanent. The reason why no one has replied to your question is because no one knows how to reverse ssri induced ED.

Otherwise you are left with viagara and those types of medications for ED.

For libido, I don't think there is a anything out there legal that boost libido and desire for sex. Some anabolic drugs increase libido... That's about the only thing that is a sure libido booster.

 

 

 

Too late for that. I've been with SSRI for a long time. SO my question is how to improve libido and erection while on SSRI.



⌛⇒ MITOMOUSE has been fully funded!

#4 maxwatt

  • Guest, Moderator LeadNavigator
  • 4,945 posts
  • 1,618
  • Location:New York

Posted 30 September 2017 - 01:28 AM

Fenugreek saponins.  Might be worth a try.



#5 Rocket

  • Guest
  • 872 posts
  • 113
  • Location:Usa
  • NO

Posted 01 October 2017 - 01:01 AM

I might really consider if you need to be on a ssri if you're having these side effects. They can become permanent. The reason why no one has replied to your question is because no one knows how to reverse ssri induced ED.

Otherwise you are left with viagara and those types of medications for ED.

For libido, I don't think there is a anything out there legal that boost libido and desire for sex. Some anabolic drugs increase libido... That's about the only thing that is a sure libido booster.




Too late for that. I've been with SSRI for a long time. SO my question is how to improve libido and erection while on SSRI.

Good luck. If you figure it out you will be a wealthy man.

Fenugreek won't help to the above post.
  • Agree x 1

#6 Darryl

  • Guest
  • 650 posts
  • 645
  • Location:New Orleans
  • NO

Posted 02 October 2017 - 12:02 AM

A couple years ago I withdrew from a 15 year course of SSRIs. No erectile dysfunction, per se, but a permanent decline/elimination of libido. My brain's simply conditioned to not care any more.

 

Fenugreek may help with testosterone, but testosterone usually isn't the problem.

 

The problem, I believe, has to do with the oppositional nature of serotonergic (mood) and dopaminergic (reward) signalling, and rather slowly shifting homeostatic adjustments to compensate for artificially elevated synaptic serotonin. A few entry points into the literature:

 

Lorrain et al, 1999. Lateral hypothalamic serotonin inhibits nucleus accumbens dopamine: implications for sexual satietyJournal of Neuroscience19(17), pp.7648-7652.

Daw et al, 2002. Opponent interactions between serotonin and dopamineNeural Networks15(4), pp.603-616.

Dremencov et al, 2009. Effects of sustained serotonin reuptake inhibition on the firing of dopamine neurons in the rat ventral tegmental areaJournal of psychiatry & neuroscience: JPN34(3), p.223.

Kranz et al, 2010. Reward and the serotonergic systemNeuroscience166(4), pp.1023-1035.

Di Giovanni et al, 2010. Role of serotonin in central dopamine dysfunctionCNS neuroscience & therapeutics16(3), pp.179-194.

Abler et al, 2012. Modulation of frontostriatal interaction aligns with reduced primary reward processing under serotonergic drugsJournal of Neuroscience32(4), pp.1329-1335.

Bijlsma et al, 2014. Sexual side effects of serotonergic antidepressants: Mediated by inhibition of serotonin on central dopamine release?Pharmacology Biochemistry and Behavior121, pp.88-101.

 

Not a pretty picture. As you may be aware, there are no quick fixes to dopamine disorders. Well there are (cocaine, methamphetamine, thorazine, L-dopa, etc), but they all have severe side effects in the long term.

 

While they offer short term benefits for a few, and placebo/nocebo effect for more, I suspect widespread, long-term prescription of SSRI antidepressants will be seen as a major healthcare fiasco. It's one thing if illegal drug abusers and nootropic self-experimenters to discover the downside to pushing on nature's levers of neurotransmitter balance, but here we have an example of the well-meaning but naive medical authorities prescribing chronic brain impairment for millions.

 

Regular exercise, sleep, conviviality. If a short term course of antidepressants helps you start these practices, good.  

 

 

 

 

 


  • Agree x 3
  • Informative x 2
  • WellResearched x 1

#7 BieraK

  • Guest
  • 257 posts
  • 48
  • Location:Arcadia
  • NO

Posted 03 October 2017 - 07:01 AM

Well for libido:
-Maca extract
-Ginseng
-Try to increased T and reduce your estrógen if are high, forskolin increases T
-Catuaba is highly libidogenic however is a dopamine and serotonin reuptake inhibitor so take care with interactions, apparently has more interactions with DAT transporter
-Muira Puama is another herb for libido commonly paired with Catuaba, I don't know the mechanism of action of this but again, apparently dopamine and serotonin receptors and transportes involved.
-Bromantane is reported as a libido enhancer due to dopamine productión increased, but I remember some studies about an increase in serotonin also, so take care because due to the strong serotonin reuptake inhibition that you already have, more serotonin could produce side effects moderates to severe like serotonin syndrome.
-Gingko is paired with Ginseng for libido,and alone works, gingko is a blood thinner and a noticeable one compared to other herbs, so take care with that, I have read in this forum about the use of vitamina mk(?) for counteracting that risk of bleeding, because vitamina mk is a coagulant, and is good for your hearth also. Gingko in doses of 120 mg or more per se increases erections.
-Buspirone is an atypical, and safest compared to benzos, anti-anxiety drug that is used for reversing ssri induced sexual dysfunction by some meds, I have used it and puts me horny. It interacts with dopamine d2 receptor and a 5-ht(?) receptor, I don't remember exactly what one, apparently 5-ht2a. If you read about ssri induced sexual dysfunction the problem is with the 5-ht1a presynaptic (autoreceptor) desensitation and at a some extent the dopamine d2 receptor (in general terms this is the motivational receptor, the d1 is the recompense/satisfaction receptor), so gingko works in 5-ht1a receptors also, thats another reason why it works for libido.
-Tianeptine sulfate, this drug works on d2 and several things, it produce an state of confidence, motivation, social interactions I don't know if works for libido do a research.

Berberine works on 5-ht1a also.... Search in this forum the user "Area-255" has done good posts about this, he is no longer in the forum apparently but the posts are still here.

The safest options for now are Maca, Ginseng (is safer compared to gingko for me) and perhaps Tongakt Ali.
Tianeptine is an atypical anti-depressant, so I don't know about interactions with ssri, but I know of some people that are changed their ssri use for Tianeptine SULFATE, that has a long half-life compared to the sodium form, so less risk of addiction and scalating doses. Tianeptine as an anti-depressant is waaaaay safer compared to ssris, has some nootropic potencial, and don't touch libido. Try to take care with this, I'm not a doctor, I don't know why you take an ssri, I don't know if you have other health problems, so you need to think a lot about this, you need to know that perhaps this could do more harm than good and is your responsability to think and take the decisión, but an option could be to take Tianeptine SULFATE instead of an ssri an try to repair your sexual health with some of the things listed, so without the ssri in your body less risks of interactions and less 5-ht1a desensitation.

I think that you have a lot of work to do and perhaps I'm complicating things, but I'm give you tons of options and ways of research, and of course the liberty of choice and responsability about freedom :).

Perhaps Buspirone is a good option?
Perhaps Maca with ginseng and tongkat could work for you?....

Edited by BieraK, 03 October 2017 - 07:27 AM.

  • like x 1

#8 jack black

  • Guest
  • 1,286 posts
  • 41
  • Location:USA
  • NO

Posted 03 October 2017 - 03:04 PM

supposedly bupropion is good for that (never tried myself).



#9 Forever21

  • Topic Starter
  • Guest
  • 1,899 posts
  • 126

Posted 03 October 2017 - 08:06 PM

Thanks. I will review.

 

But for Buspirone - this is the problem.

 

Buspirone is not known to be effective in the treatment of other anxiety disorders besides GAD ("Buspirone: Back to the Future". J Psychosoc Nurs Ment Health Serv. 53 (11): 21–4. PMID 26535760. doi:10.3928/02793695-20151022-01.)
 
I have social anxiety disorder.
 
 

Well for libido:
-Maca extract
-Ginseng
-Try to increased T and reduce your estrógen if are high, forskolin increases T
-Catuaba is highly libidogenic however is a dopamine and serotonin reuptake inhibitor so take care with interactions, apparently has more interactions with DAT transporter
-Muira Puama is another herb for libido commonly paired with Catuaba, I don't know the mechanism of action of this but again, apparently dopamine and serotonin receptors and transportes involved.
-Bromantane is reported as a libido enhancer due to dopamine productión increased, but I remember some studies about an increase in serotonin also, so take care because due to the strong serotonin reuptake inhibition that you already have, more serotonin could produce side effects moderates to severe like serotonin syndrome.
-Gingko is paired with Ginseng for libido,and alone works, gingko is a blood thinner and a noticeable one compared to other herbs, so take care with that, I have read in this forum about the use of vitamina mk(?) for counteracting that risk of bleeding, because vitamina mk is a coagulant, and is good for your hearth also. Gingko in doses of 120 mg or more per se increases erections.
-Buspirone is an atypical, and safest compared to benzos, anti-anxiety drug that is used for reversing ssri induced sexual dysfunction by some meds, I have used it and puts me horny. It interacts with dopamine d2 receptor and a 5-ht(?) receptor, I don't remember exactly what one, apparently 5-ht2a. If you read about ssri induced sexual dysfunction the problem is with the 5-ht1a presynaptic (autoreceptor) desensitation and at a some extent the dopamine d2 receptor (in general terms this is the motivational receptor, the d1 is the recompense/satisfaction receptor), so gingko works in 5-ht1a receptors also, thats another reason why it works for libido.
-Tianeptine sulfate, this drug works on d2 and several things, it produce an state of confidence, motivation, social interactions I don't know if works for libido do a research.

Berberine works on 5-ht1a also.... Search in this forum the user "Area-255" has done good posts about this, he is no longer in the forum apparently but the posts are still here.

The safest options for now are Maca, Ginseng (is safer compared to gingko for me) and perhaps Tongakt Ali.
Tianeptine is an atypical anti-depressant, so I don't know about interactions with ssri, but I know of some people that are changed their ssri use for Tianeptine SULFATE, that has a long half-life compared to the sodium form, so less risk of addiction and scalating doses. Tianeptine as an anti-depressant is waaaaay safer compared to ssris, has some nootropic potencial, and don't touch libido. Try to take care with this, I'm not a doctor, I don't know why you take an ssri, I don't know if you have other health problems, so you need to think a lot about this, you need to know that perhaps this could do more harm than good and is your responsability to think and take the decisión, but an option could be to take Tianeptine SULFATE instead of an ssri an try to repair your sexual health with some of the things listed, so without the ssri in your body less risks of interactions and less 5-ht1a desensitation.

I think that you have a lot of work to do and perhaps I'm complicating things, but I'm give you tons of options and ways of research, and of course the liberty of choice and responsability about freedom :).

Perhaps Buspirone is a good option?
Perhaps Maca with ginseng and tongkat could work for you?....

 



⌛⇒ MITOMOUSE has been fully funded!

#10 Rocket

  • Guest
  • 872 posts
  • 113
  • Location:Usa
  • NO

Posted 05 October 2017 - 01:00 AM

Well for libido:
-Maca extract
-Ginseng
-Try to increased T and reduce your estrógen if are high, forskolin increases T
-Catuaba is highly libidogenic however is a dopamine and serotonin reuptake inhibitor so take care with interactions, apparently has more interactions with DAT transporter
-Muira Puama is another herb for libido commonly paired with Catuaba, I don't know the mechanism of action of this but again, apparently dopamine and serotonin receptors and transportes involved.
-Bromantane is reported as a libido enhancer due to dopamine productión increased, but I remember some studies about an increase in serotonin also, so take care because due to the strong serotonin reuptake inhibition that you already have, more serotonin could produce side effects moderates to severe like serotonin syndrome.
-Gingko is paired with Ginseng for libido,and alone works, gingko is a blood thinner and a noticeable one compared to other herbs, so take care with that, I have read in this forum about the use of vitamina mk(?) for counteracting that risk of bleeding, because vitamina mk is a coagulant, and is good for your hearth also. Gingko in doses of 120 mg or more per se increases erections.
-Buspirone is an atypical, and safest compared to benzos, anti-anxiety drug that is used for reversing ssri induced sexual dysfunction by some meds, I have used it and puts me horny. It interacts with dopamine d2 receptor and a 5-ht(?) receptor, I don't remember exactly what one, apparently 5-ht2a. If you read about ssri induced sexual dysfunction the problem is with the 5-ht1a presynaptic (autoreceptor) desensitation and at a some extent the dopamine d2 receptor (in general terms this is the motivational receptor, the d1 is the recompense/satisfaction receptor), so gingko works in 5-ht1a receptors also, thats another reason why it works for libido.
-Tianeptine sulfate, this drug works on d2 and several things, it produce an state of confidence, motivation, social interactions I don't know if works for libido do a research.

Berberine works on 5-ht1a also.... Search in this forum the user "Area-255" has done good posts about this, he is no longer in the forum apparently but the posts are still here.

The safest options for now are Maca, Ginseng (is safer compared to gingko for me) and perhaps Tongakt Ali.
Tianeptine is an atypical anti-depressant, so I don't know about interactions with ssri, but I know of some people that are changed their ssri use for Tianeptine SULFATE, that has a long half-life compared to the sodium form, so less risk of addiction and scalating doses. Tianeptine as an anti-depressant is waaaaay safer compared to ssris, has some nootropic potencial, and don't touch libido. Try to take care with this, I'm not a doctor, I don't know why you take an ssri, I don't know if you have other health problems, so you need to think a lot about this, you need to know that perhaps this could do more harm than good and is your responsability to think and take the decisión, but an option could be to take Tianeptine SULFATE instead of an ssri an try to repair your sexual health with some of the things listed, so without the ssri in your body less risks of interactions and less 5-ht1a desensitation.

I think that you have a lot of work to do and perhaps I'm complicating things, but I'm give you tons of options and ways of research, and of course the liberty of choice and responsability about freedom :).

Perhaps Buspirone is a good option?
Perhaps Maca with ginseng and tongkat could work for you?....

None of these over the counter supps will do anything for SSRI induced sexual dysfunction. That's why there are forums full of people with sexual dysfunction all looking for answers.

I have known people with this and its wishful thinking that ginseng or Maca or xyz is going counteract SSRI sexual dysfunction.

Yohimbe can mildly help with erections in some people. But... Good luck with the side effects because you want want sex after taking it.

I know people who have tried requip to overcome ssri induced sexual dysfunction and no success. Even very high doses did nothing.

If I had to deal with social anxiety and no sex or sex and social anxiety there would be no contest.... Sex every time! But that's me and I don't care what people think of me which is what social anxiety is all about.

I took elavil briefly for insomnia and when weird things started with my sex life, I dropped it like a bad habit.

Seek out proven things... Viagara, cialis, injections...

Good luck bro!

Edited by Rocket, 05 October 2017 - 01:06 AM.


#11 NHP

  • Guest
  • 7 posts
  • 2
  • Location:UK
  • NO

Posted 05 October 2017 - 11:19 AM

Try Longjack (tongkat ali)  it gives strong desire.


  • dislike x 1
  • Disagree x 1

#12 Rocket

  • Guest
  • 872 posts
  • 113
  • Location:Usa
  • NO

Posted 06 October 2017 - 01:41 AM

So yeah, pramipexole and high doses of requip allegedly help to counteract ssri sexual dysfunction but I don't know of any reviews that back that up.

The only thing I have experienced that made me a sex hound was high doses of testosterone on the order of over .5g weekly. I've heard proviron makes a lot of guys super horny.

#13 Kodiak

  • Guest
  • 25 posts
  • 4
  • Location:Madison, WI
  • NO

Posted 06 October 2017 - 06:55 PM

Proviron certainly helped in the erection department for me. I imagine Test and Proviron would be quite the potent tandem. However, Proviron also killed my HDL so if anyone was to consistently take it I'd monitor your cholesterol level with blood tests/labs. 



#14 Rocket

  • Guest
  • 872 posts
  • 113
  • Location:Usa
  • NO

Posted 13 October 2017 - 02:29 PM

Proviron certainly helped in the erection department for me. I imagine Test and Proviron would be quite the potent tandem. However, Proviron also killed my HDL so if anyone was to consistently take it I'd monitor your cholesterol level with blood tests/labs. 

 

Even high doses of testosterone will kill a person's HDL. I think adverse effects start to show around 150mg/week. That's why all these lunatics taking 200mg a week thinking they are reverse aging are actually hurting themselves. Not to mention the increase RBC you get from high doses of testosterone and almost any amount at all of any anabolic like proviron or masteron.

 

Back to topic, requip, amantadine, trazadone, and pramipexole, (the legal drugs) are all said to help.

 

Melanotan and PT141 are peptides said to be able to help.



#15 Rocket

  • Guest
  • 872 posts
  • 113
  • Location:Usa
  • NO

Posted 25 October 2017 - 01:41 AM

Here is some reading material for the OP...

https://pssdlab.word...ful-treatments/

Apparently hypercium in my brief 5 minute google search increases 5ht1 and 5ht2 receptors which ssri drugs seem to damage. Never knew St Johns Wort did that.

Over on peak testosterone someone claims vitamin c and garlic help.

Edited by Rocket, 25 October 2017 - 01:46 AM.


#16 Charles Thompson

  • Guest
  • 63 posts
  • 0
  • Location:UK
  • NO

Posted 27 October 2017 - 06:22 AM

The thing which in my view has worked better than anything is the dopamine agonist cabergoline. It’s nothing short of incredible as far as it’s ability to massively increase libido and allow for repeat sex sessions with minimal rest.

Not even testosterone comes close.

⌛⇒ MITOMOUSE has been fully funded!

#17 Cassandra

  • Guest
  • 11 posts
  • 2
  • Location:United States
  • NO

Posted 27 October 2017 - 12:54 PM

I was on Cipralex last year for six months. Before I started treatment my Libido was low anyway, however after 3 weeks on Cipralex it was nonexistant. I just don’t think SSRIs are very good in general


0 user(s) are reading this topic

0 members, 0 guests, 0 anonymous users