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What happened to Adipotide? Sounded like a game changer for obesity and general health.

weight loss

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#1 YOLF

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Posted 29 October 2017 - 02:44 PM


Last I heard, having lots of fat cells die was particularly painful, something I could live with if it meant being skinny and have a nice flat stomach. 

 

Has anybody heard anything? Or did our pharmaceutical overlords decide that we couldn't trade pain for health and wouldn't want it?

 

Or did adipotide turn out to have "Krokodil" (Russian street drug that kills you) like effects in some minority of users? For those who don't know, Adipotide targets the blood supply of white fat cells via two receptors which are only expressed in said cells. Otherwise, the action of Adipotide isn't much different from Krokodil, except that Krokodil just kills anything attached to your heart.

 

Cheers to hoping it's safe and that it becomes available. Hopefully anyone buying it from peptide sellers will document their results... I'm also wondering how it affects the look of skin cosmetically and hoping it won't make the patient look like a rumpled sack of potatoes.



#2 Mind_Paralysis

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Posted 15 June 2018 - 07:42 AM

Scroll down the comments in this blog, and you will find the info:
 

http://www.powerfulh...ss-falls-radar/

 

It would appear as if the people whom were developing the drug, got new jobs at a different company. Meanwhile, the company that holds the patent, had economic problems and instead went with a drug for the treatment of Hepatitis B - which, admittedly, there's several new, and successful, drugs for - they figured it would be more of a sure hit, and went with that.

 

There's also some speculation, that some of the side-effects of the drug, seen only in people whom took it online, may have been from impurities in the chemical, since the companies supplying it, had either A: not intended it for human trial, or B: are shifty and don't really care.

 

(not everybody has the same rigorous controls as Ceretropic, you know...)

 

 

I would agree that it seems like a wonderful idea for a drug! = ) Amazing if someone bought the rights and went back to human testing again. Usually, I would be very cautious of an apoptotic drug, but this one actually seems very, very selective.

 

Btw, Krokodil-like side-effects would have been found in animal-trials - they use thousands of rats for those - eventually it would have showed up.



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#3 YOLF

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Posted 15 June 2018 - 02:13 PM

I wonder if it qualifies for orphan drug status? I mention krokodil, but if it's not indiscriminate, it'll probably be better for cardiovascular health. 

 

Then again, what's it going to do to your face? But there's inexpensive stuff at dermatologists that could be used to fix this problem if it occurs.







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