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Nuerotoxicity from drug use please help

brain damage nuerotoxicity health depression anhedonia

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#1 Andersen

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Posted 20 February 2018 - 12:35 AM


During my late high school career i was using alot of drugs. Anything and everything you could think of but mainly stimulants. I did alot of what i thought to be MDMA, i guess it could have been anything and took a good bit of adhd medicine (whatever i could find) including vyvanse, adderall, ritalin, ect. for school purposes and just in general to make me feel good. Note that i was never prescribed it or diagnosed with adhd so had no reason to be taking it.I stated to develop a bit of a habit. I was an avid pot smoker and drank about every weekend. I started to notice myself changing but was unaware that this was why. I was so caught up in getting fucked up nothing else mattered. I didnt think anything would huurt me. Man was i wrong. I started to develop very bad attitude problems, and got mean. Things really changed after graduating and starting a community college. I consistantly bough adderall/vyvanse from friends for the first semester which was probably about six months and took it probably 3-4 times a week. Ranging from all mg levels that are prescribed. After that first semester i felt sick. Sick mentally and physically. i quit everything, began eating right, and taking supplements. after about three months i felt better but never returned to my older self. After a while i began smoking pot again and also drinking. I was able to function but not well and was still not happy like i used to be prior to any drug use. I didnt realize the toll drugs had taken on me. eventally i decided to take a couple grams of mushrooms. I ate about 3g of mushroom one night, had a very uncomfortable trip, and have not been right since. I declined mentally afterwards, and did not sleep for three weeks. I think the mushrooms must have exacerbated the damage from drugs but i am not sure.

 

Since then i have been stuggling with Memory problems, what i think to be adrenal fatigue, vision problems, anhedonia, lack of personality, irritation, i cant sleep good at all anymore (its just not a good deep sleep anymore), i have a hard time remembering what i just did, thinking things through, i have no sense of how i feel or what i want, cant decide between two things, experience no pleasure, cant make rational decisions, have no motivation or drive to do anything, have a very hard time reading a book or following a movie anymore, lack of awarness and also explaining myself. I eat so much food anymore and cannot get satisfied. I dont enjoy hanging out or converssating with others anymore and feel like an alien.

 

After hours and hours of searching around and reading up on things i beleive this to be brain damage caused by amphetimines/stimulants and drugs in general. Im 19 years old and feel like im 80. It feels like their is a big hole in my head and all i want to do is somehow get back to the old me. I am currently sober, taking vitamins, and eating a plant based diet. I am looking into nootropics and also bpc-157 for repair. I am wondering with sobriety and a good healthy lifestyle, if i will ever potentially heal from this or my dopaminergic sistem will ever fully recover so i can enjoy life and be a functioning person again. has anyone else had any problems with this or does anybody know of anything that may for sure help my situation. i am looking for any information that anybody can provide. Would bpc157 help me with no side effects or without causeing anymore damage?? how much? Where should i seek help? i have been diagnosed with depression but fear taking meds for causing more damage. I just want to live a normal sober life

 

 



#2 tunt01

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Posted 20 February 2018 - 01:10 AM

Eat in a 6 hour window (ex.  12 pm - 6 pm).

 

Do not eat a pure plant based diet.  Include fish, chicken, some form of animal protein.  Check your B12 levels and supplement B12 if it is below 400 pg/mL.

 

No alcohol more than a couple ounces (wine, etc.).

 

Try to limit caffeine, unless you know you are a high metabolizer of caffeine (genetically).  Suggest you stick to green/white tea.

 

Get aerobic exercise every day.  Run 3-5 miles ideally or switch it up every day, sprinting HIIT one day and long distance light running 2-3 miles the next.

 

Maybe use Lion's mane in your tea, low dose lithium in the AM while fasted.

 

Some supplemental choline, uridine with food.

 

Do not take prescription pills/significant nootropics to fix your problems for the next 6 months and let the brain heal naturally.

 

 

 


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#3 Andersen

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Posted 20 February 2018 - 02:36 AM

Eat in a 6 hour window (ex.  12 pm - 6 pm).

 

Do not eat a pure plant based diet.  Include fish, chicken, some form of animal protein.  Check your B12 levels and supplement B12 if it is below 400 pg/mL.

 

No alcohol more than a couple ounces (wine, etc.).

 

Try to limit caffeine, unless you know you are a high metabolizer of caffeine (genetically).  Suggest you stick to green/white tea.

 

Get aerobic exercise every day.  Run 3-5 miles ideally or switch it up every day, sprinting HIIT one day and long distance light running 2-3 miles the next.

 

Maybe use Lion's mane in your tea, low dose lithium in the AM while fasted.

 

Some supplemental choline, uridine with food.

 

Do not take prescription pills/significant nootropics to fix your problems for the next 6 months and let the brain heal naturally.

okay i am doing most of this except for fasting in the am. Can you explain to me how many times i should eat between 12 and 6 and why it is important for me to fast in the am? are my supplements okay for the am and should i quit coq10? it does not seem to be doing much for me



#4 tunt01

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Posted 20 February 2018 - 12:06 PM

CoQ10 is associated with reduced lifespan in mice and is unnecessary.

 

I'd say eating twice between 12-6 PM is fine, but whatever works for your body is fine.  It will be uncomfortable the first 2-3 days fasting in the AM, then you will adjust.  It will put your body into mild ketosis and create a mild stress that stimulates bdnf and forces the brain to be challenged.

 

You can get an Abbott Precision Xtra to see if your body shifts into mild ketosis before eating at 12 PM. 



#5 Andersen

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Posted 20 February 2018 - 12:45 PM

CoQ10 is associated with reduced lifespan in mice and is unnecessary.

 

I'd say eating twice between 12-6 PM is fine, but whatever works for your body is fine.  It will be uncomfortable the first 2-3 days fasting in the AM, then you will adjust.  It will put your body into mild ketosis and create a mild stress that stimulates bdnf and forces the brain to be challenged.

 

You can get an Abbott Precision Xtra to see if your body shifts into mild ketosis before eating at 12 PM. 

Thank you so much for your quick and helpful replies. How do you know when the body has entered mild ketosis by testing the blood glucose.

As for vitamins i am currently taking:

50 mg of iron bisglycinate

2 adaptocrine supplements for adrenal support

1 b supreme  (b complex)

100mg of magnesium glycinate Complex

30mg of zinc

2000 iu of vitamin D

and around 3.75 g of fish oil a day with 750mgDha and epa

 

i Should be getting the uridine/choline in the mail pretty soon. How much of those two would you reccomend? Are these supplements okay/ necessary?

The only things i was low in when i had a blood test done was i think iron and vitamin d.



#6 sthira

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Posted 20 February 2018 - 01:38 PM

In addition to the solid advice prophets has given you, I'd add the obvious, to slow down the partying for awhile. I realize it's really hard to hang out with friends and maintain relationships without "having fun" (mostly translated as getting wasted) but that's what I'd do. As far as diet: avoid junk food and sugary drinks, and try to eat more things you recognize as unprocessed.

Also I think if I were you I'd avoid almost every vitamin supplement, experimental nootropic, and unprescribed drug that's being given or marketed to you. You're 19. Your body should have plenty of regenerative power -- even if you've temporarily abused it. I'm just assuming you've already checked in with appropriate doctors and you're general a healthy, normally functioning 19-year old. (?)

To heal your brain from past drug excursions, consider staying in school and focusing on what you want to do with your life. Find your passion is the cliche, and you may roll your eyes at advice to find your passion; but applying yourself to something positive -- anything -- sounds like what you need. Consider studying the sciences, for example, study biology or chemistry or physics -- whatever floats your boat, this is your life. I think pursuing your dreams is a good plan to help heal you and give you hope for the future.

#7 tunt01

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Posted 20 February 2018 - 02:29 PM

Thank you so much for your quick and helpful replies. How do you know when the body has entered mild ketosis by testing the blood glucose.

 

 

As for vitamins i am currently taking:

50 mg of iron bisglycinate

2 adaptocrine supplements for adrenal support

1 b supreme  (b complex)

100mg of magnesium glycinate Complex

30mg of zinc

2000 iu of vitamin D

and around 3.75 g of fish oil a day with 750mgDha and epa

 

i Should be getting the uridine/choline in the mail pretty soon. How much of those two would you reccomend? Are these supplements okay/ necessary?

The only things i was low in when i had a blood test done was i think iron and vitamin d.

 

 

If you are vegan/vegetarian, maybe iron makes sense.  I wouldn't go vegetarian though.

 

I don't see why you need adrenal support or what or how you define adrenal fatigue.  It seems like nonsense to me.

 

30 mg Zinc is fine.  2000 IU vitamin D is fine. 

 

100 mg magnesium is fine.  I would favor magnesium threonate, which has been shown to stimulate neurogenesis.

 

B vitamin complex is probably OK, but maybe unnecessary.  It really depends on your diet.  If your diet is chicken and white rice, with minimal vegetables, then you need a B complex.  If your diet is heavy in leafy greens/veggies, chicken/shrimp, then you probably don't need a b-complex and maybe not even magnesium.

 

I probably would not take fish oil and favor flaxseed.  There are some positive studies on fish oil, but there are also a few negatives/concerns that outweigh the risk to me.  It just doesn't seem worthwhile.  Eat fish 2x a week and skip the oils.

 

 

Take the supplements with a meal.  Do not take supplements during a fasting period, unless they are meant to augment fasting (lithium is....).


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#8 Andersen

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Posted 20 February 2018 - 09:22 PM

i have just gotten uridine 300 and alphagpc 500mg in the mail.

Should i suplement these?

So i should just take the zinc, vitd and magnesium? or should i not take these either? i eat enough greens and also meats. i have been eating fish twice a week.

im somewhat confused whether to take supplements or just let it heal naturally. 

i usually eat lunch and dinner between 12 and 5pm so ill just start skipping breakfast and this should help me?

i feel like i have been doing alot of this but i must have caused some pretty severe damage because i dont feel anything like my old self and have been struggling with these problems for about a year. are you sure it will get better?



#9 Andersen

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Posted 21 February 2018 - 12:41 AM

 

Thank you so much for your quick and helpful replies. How do you know when the body has entered mild ketosis by testing the blood glucose.

 

 

As for vitamins i am currently taking:

50 mg of iron bisglycinate

2 adaptocrine supplements for adrenal support

1 b supreme  (b complex)

100mg of magnesium glycinate Complex

30mg of zinc

2000 iu of vitamin D

and around 3.75 g of fish oil a day with 750mgDha and epa

 

i Should be getting the uridine/choline in the mail pretty soon. How much of those two would you reccomend? Are these supplements okay/ necessary?

The only things i was low in when i had a blood test done was i think iron and vitamin d.

 

 

If you are vegan/vegetarian, maybe iron makes sense.  I wouldn't go vegetarian though.

 

I don't see why you need adrenal support or what or how you define adrenal fatigue.  It seems like nonsense to me.

 

30 mg Zinc is fine.  2000 IU vitamin D is fine. 

 

100 mg magnesium is fine.  I would favor magnesium threonate, which has been shown to stimulate neurogenesis.

 

B vitamin complex is probably OK, but maybe unnecessary.  It really depends on your diet.  If your diet is chicken and white rice, with minimal vegetables, then you need a B complex.  If your diet is heavy in leafy greens/veggies, chicken/shrimp, then you probably don't need a b-complex and maybe not even magnesium.

 

I probably would not take fish oil and favor flaxseed.  There are some positive studies on fish oil, but there are also a few negatives/concerns that outweigh the risk to me.  It just doesn't seem worthwhile.  Eat fish 2x a week and skip the oils.

 

 

Take the supplements with a meal.  Do not take supplements during a fasting period, unless they are meant to augment fasting (lithium is....).

 

 



#10 zeropoint

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Posted 21 February 2018 - 02:25 PM

I want to add Uridine also as supplement to my regime, from what I've read it sounds excellent for nuerological issues....though a bit expensive.

 

I like and use alpha lipoic acid (150mg. morning and night) and L-acetyl carnitine 500mg. morning only. Both also good for nuerological issues.

 

ALA(alpha-lipoic acid) has an added benefit of chelating mercury out of the body,something you may have not considered.

 (Mercury is definitely nuerotoxic and you can feel worse before feeling better)

 

Plant-based diet sounds healthier in the long run(though as of late I've been getting meat cravings) and have been lapsing...please see Dr. John McDougall on youtube to make your own mind up.


Edited by zeropoint, 21 February 2018 - 02:28 PM.


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#11 Andersen

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Posted 22 February 2018 - 01:01 PM

Can i drink water after running while intermittent fasting?

 

Thank you so much for your quick and helpful replies. How do you know when the body has entered mild ketosis by testing the blood glucose.

 

 

As for vitamins i am currently taking:

50 mg of iron bisglycinate

2 adaptocrine supplements for adrenal support

1 b supreme  (b complex)

100mg of magnesium glycinate Complex

30mg of zinc

2000 iu of vitamin D

and around 3.75 g of fish oil a day with 750mgDha and epa

 

i Should be getting the uridine/choline in the mail pretty soon. How much of those two would you reccomend? Are these supplements okay/ necessary?

The only things i was low in when i had a blood test done was i think iron and vitamin d.

 

 

If you are vegan/vegetarian, maybe iron makes sense.  I wouldn't go vegetarian though.

 

I don't see why you need adrenal support or what or how you define adrenal fatigue.  It seems like nonsense to me.

 

30 mg Zinc is fine.  2000 IU vitamin D is fine. 

 

100 mg magnesium is fine.  I would favor magnesium threonate, which has been shown to stimulate neurogenesis.

 

B vitamin complex is probably OK, but maybe unnecessary.  It really depends on your diet.  If your diet is chicken and white rice, with minimal vegetables, then you need a B complex.  If your diet is heavy in leafy greens/veggies, chicken/shrimp, then you probably don't need a b-complex and maybe not even magnesium.

 

I probably would not take fish oil and favor flaxseed.  There are some positive studies on fish oil, but there are also a few negatives/concerns that outweigh the risk to me.  It just doesn't seem worthwhile.  Eat fish 2x a week and skip the oils.

 

 

Take the supplements with a meal.  Do not take supplements during a fasting period, unless they are meant to augment fasting (lithium is....).

 

 







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