https://en.wikipedia.../wiki/Bupropion
Under the wikipedia Pharmacology it says:
Inhibition potency =
DA uptake 100%
NE uptake 27%
Im confused... Isnt it supposed to be the opposite? 100% NE Uptake and 27% DA uptake? I `thought Wellbutrin was a weak Dopamine inhibitor. So why is wikipedia saying the opposite ?
The occupancy of dopamine transporter (DAT) sites by bupropion and its metabolites in the human brain as measured by positron emission tomography was 26% according to GlaxoSmithKline researchers and 14% in an independent study.
Edited by farshad, 03 March 2018 - 06:21 PM.