L-Arginine and sleep
chilp 28 Apr 2009
I have a slight sleep apnea condition but my doctor said according to the sleep lab results that it wasn't significant enough to cause those problems.
I have tried everything form herbal stuff to benzos, including tryptophan/5.htp/phenibut and others, to my unsatisfaction.
The other night ,I was feeling a little anxious, and remembered that I had Arginibne in stock, so I thought why not, as an alternative to Theanine or benzos. I took 1000mg.
And guess what, i woke up the following day completely refreshed and in a good mood. So I decided to pursue the experience and to take 1000mg for the following days.
Let me tell you that it's been a massive success so far, waking up upon alarm call and all.
It seems I haven't read anything about Arginine and sleep, have you guys any idea or clue r experience about that ?
Thorsten3 28 Apr 2009
simon007 28 Apr 2009
I use Arginine to as a sleeping aid and it work's very well. I take about 5 mg 30 minutes before I go to bed. Arginine stimulates HGH, I think that's the reason it works as a sleeping aid. I'm planning to try citrullina, because it's raises the arginine in the body more than Arginine itself. This is because the liver brakes down Arginine.
Cheers,
Simon
chilp 29 Apr 2009
Thorsten3 12 Oct 2009
Hi Chilp,
I use Arginine to as a sleeping aid and it work's very well. I take about 5 mg 30 minutes before I go to bed. Arginine stimulates HGH, I think that's the reason it works as a sleeping aid. I'm planning to try citrullina, because it's raises the arginine in the body more than Arginine itself. This is because the liver brakes down Arginine.
Cheers,
Simon
5mg?? Jeez it must send you to sleep trying to cut your 500mg tablet down to that level
Lufega 13 Oct 2009
easygoer 14 Oct 2009
Smriga M, Ando T, Akutsu M, Furukawa Y, Miwa K, Morinaga Y.Institute of Life Sciences, Ajimoto Co. Inc, 1-1 Suzuki-cho, 210-8681 Kawasaki-ku, Kawasaki-shi, Japan. miro_smriga@ehq.ajinomoto.com
Dietary supplementation with an essential amino acid L-lysine has been shown to reduce chronic anxiety in humans with low dietary intake of L-lysine. A combination of L-lysine and L-arginine has been documented to normalize hormonal stress responses in humans with high trait anxiety. The present study was carried out in one hundred eight healthy Japanese adults. The aim of study was to find out whether a week-long oral treatment with L-lysine (2.64 g per day) and L-arginine (2.64 g per day) reduces trait and stress-induced state anxiety and basal levels of stress hormones. We confirmed that, without regard to gender, the amino acid treatment significantly reduced both trait anxiety and state anxiety induced by cognitive stress battery. In addition, we found that the treatment with L-lysine and L-arginine decreased the basal levels of salivary cortisol and chromogranin-A (a salivary marker of the sympatho-adrenal system) in male subjects. These results of this double-blind, placebo controlled and randomized study confirm the previous findings in humans and animals and point to a combination of L-lysine and L-arginine as a potentially useful dietary intervention in otherwise healthy humans with high subjective levels of mental stress and anxiety.
Thorsten3 14 Oct 2009
Oral treatment with L-lysine and L-arginine reduces anxiety and basal cortisol levels in healthy humans.
Smriga M, Ando T, Akutsu M, Furukawa Y, Miwa K, Morinaga Y.Institute of Life Sciences, Ajimoto Co. Inc, 1-1 Suzuki-cho, 210-8681 Kawasaki-ku, Kawasaki-shi, Japan. miro_smriga@ehq.ajinomoto.com
Dietary supplementation with an essential amino acid L-lysine has been shown to reduce chronic anxiety in humans with low dietary intake of L-lysine. A combination of L-lysine and L-arginine has been documented to normalize hormonal stress responses in humans with high trait anxiety. The present study was carried out in one hundred eight healthy Japanese adults. The aim of study was to find out whether a week-long oral treatment with L-lysine (2.64 g per day) and L-arginine (2.64 g per day) reduces trait and stress-induced state anxiety and basal levels of stress hormones. We confirmed that, without regard to gender, the amino acid treatment significantly reduced both trait anxiety and state anxiety induced by cognitive stress battery. In addition, we found that the treatment with L-lysine and L-arginine decreased the basal levels of salivary cortisol and chromogranin-A (a salivary marker of the sympatho-adrenal system) in male subjects. These results of this double-blind, placebo controlled and randomized study confirm the previous findings in humans and animals and point to a combination of L-lysine and L-arginine as a potentially useful dietary intervention in otherwise healthy humans with high subjective levels of mental stress and anxiety.
interesting. I've taken l-arigine for the past couple of nights and it has actually knocked me straight out. This has suprised me. When I purchased it I was looking for the libido qualities but it does seem to help with sleep. The 2 nights I have tried it my mind has been racing plus I've had the expectation of the supplement aiding with my sleep. On both occasions so far it has worked very well although you can never discount placebo.
This case study related to anxiety is very interesting. Is there anyone here who has tried lysine + arigine for anxiety?
simon007 14 Oct 2009
Typo :-) it use to be 5 gramsHi Chilp,
I use Arginine to as a sleeping aid and it work's very well. I take about 5 mg 30 minutes before I go to bed. Arginine stimulates HGH, I think that's the reason it works as a sleeping aid. I'm planning to try citrullina, because it's raises the arginine in the body more than Arginine itself. This is because the liver brakes down Arginine.
Cheers,
Simon
5mg?? Jeez it must send you to sleep trying to cut your 500mg tablet down to that level
At the moment I'm using 3 grams Arginine and d 2 gram Citulline, still works very well..
Cheers,
Simon
wolfeye 15 Oct 2009
Growth hormone, arginine and exercise.
Recent studies have shown that resting growth hormone responses increase with oral ingestion of L-arginine and the dose range is 5-9 g of arginine. Within this range there is a dose-dependent increase and higher doses are not well tolerated. Most studies using oral arginine have shown that arginine alone increases the resting growth hormone levels at least 100%, while exercise can increase growth hormone levels by 300-500%. The combination of oral arginine plus exercise attenuates the growth hormone response, however, and only increases growth hormone levels by around 200% compared to resting levels. SUMMARY: Exercise is a very potent stimulator of growth hormone release and there is considerable research documenting the dramatic growth hormone rise. At rest oral L-arginine ingestion will enhance the growth hormone response and the combination of arginine plus exercise increases growth hormone, but this increase may be less than seen with exercise alone. This diminished response is seen in both in both younger and older individuals.
http://www.ncbi.nlm....pubmed/18090659
Edited by Wolf-Eye, 15 October 2009 - 04:33 PM.
KimberCT 15 Oct 2009
Hahahaha, um... no.Actually, you know sometimes you yawn and at the same time you get an erection?
I've been taking 4 grams Arginine in the AM for a couple of weeks and found that it helps relieve tremors. I've found no studies to back this up but it's working for me. I'm using an arginine/ornithine combo but this has not had that viagra effect on me.
Tremors... interesting. Do you have essential tremor? I haven't tried arginine for this, but I can attest to the viagra effect.
wolfeye 16 Oct 2009
Central L-arginine reduced stress responses are mediated by L-ornithine in neonatal chicks.
Recently, we observed that central administration of L-arginine attenuated stress responses in neonatal chicks, but the contribution of nitric oxide (NO) to this response was minimal. The sedative and hypnotic effects of L-arginine may be due to L-arginine itself and/or its metabolites, excluding NO. To clarify the mechanism, the effect of intracerebroventricular (i.c.v.) injection of L-arginine metabolites on behavior under social separation stress was investigated. The i.c.v. injection of agmatine, a guanidino metabolite of L-arginine, had no effect during a 10 min behavioral test. In contrast, the i.c.v. injection of L-ornithine clearly attenuated the stress response in a dose-dependent manner, and induced sleep-like behavior. The L-ornithine concentration in the telencephalon and diencephalon increased following the i.c.v. injection of L-arginine. In addition, several free amino acids including L-alanine, glycine, L-proline and L-glutamic acid concentrations increased in the telencephalon. In conclusion, it appears that L-ornithine, produced by arginase from L-arginine in the brain, plays an important role in the sedative and hypnotic effects of L-arginine observed during a stress response. In addition, several other amino acids having a sedative effect might partly participate in the sedative and hypnotic effects of L-arginine.
http://www.ncbi.nlm....Pubmed_RVDocSum
Edited by Wolf-Eye, 16 October 2009 - 12:11 PM.
matter_of_time 16 Oct 2009
http://www.ncbi.nlm....3?dopt=Abstract
Ahab Blutarski 06 Apr 2010
Logan 07 Apr 2010
Thanks for posting. I've hadn't slept fully through the night in years, years, years. L-Arginine in this area was a complete surprize. Thank you for your post. I just woke up and decided to google Arginine and sleep to see if anyone else had similar experience.
So you have tried Arginine and it did work for you?