theaflavins are senolytic?
sedentary
15 Jan 2020
i didnt know this about theaflavins but then i read this article; https://www.lifeexte...senescent-cells
so whats the deal with theaflavins. i know lifeextension usually exaggerates so they sell more products but the article does have good points. do you think theaflavins can fall into the senolytic category??
kench
11 Feb 2020
I am using the LEF senolytic product, but I don't have much to report on as of now.
Iporuru
12 Feb 2020
Reducing Hypothalamic Stem Cell Senescence Protects against Aging-Associated Physiological Decline
Highlights
- The lncRNA Hnscr is highly expressed in htNSCs of young mice but decreases during aging
- Hnscr depletion promotes the senescence of htNSCs and aging-like phenotypes
- Hnscr attenuates htNSC senescence by binding to YB-1 to prevent its degradation
- Theaflavin 3-gallate mimics Hnscr and ameliorates aging-related physiological disorders
Summary
Edited by Iporuru, 12 February 2020 - 06:14 AM.
johnross47
20 Feb 2020
I treat myself with this stuff every day; usually about a litre of tea.
sedentary
21 Feb 2020
a liter of water might be fine, but tea... i even know some people having that much coffee too. not sure its good for you long term
johnross47
09 Mar 2020
I've been drinking tea since I was a child, like many people in the UK and I'm 73 now. I've never seen anything that made it look at all dangerous or harmful.
sedentary
10 Mar 2020
oh wow so you probably consumed a lot of theaflavins in your life. i mean, what, like 60 years regularly perhaps? tea also contains quercetin. so i guess you should be experiencing senescence. can you feel it or see it somehow? probably take a test, like one of those telemores DNA tests
johnross47
19 Mar 2020
I probably was introduced to tea by the time I was about 7 or 8, but being Scottish, it was drunk with quite a bit of milk, which would soak up the oxalic acid component. I take a lot less milk now, but still some.
johnross47
20 Mar 2020
Interesting...I usually drink green tea neat as they say, and black tea with a small amount of milk ....I must measure how much. I could probably learn to drink it black, but then of course there would be the oxalic acid issue.??????
sedentary
22 Mar 2020
Correct, adding milk to tea negates its beneficial properties.
any chance on figuring out which type of black teas contain what amount of theaflavins?
