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Epigenetic Tests #1 and 2: Horvath, Hannum...

Krell's Photo Krell 29 Aug 2022

Very interesting.  Is the DunedinPACE test available for purchase?

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albedo's Photo albedo 30 Aug 2022

Excellent Michael!

However to a first quick comment (sorry, not much time to think about this now, hopefully I got it right):

1. wonder about significance of 0.6 vs 0.8 in DunedinPACE in a short period of time, but results are very encouraging!

2. confirm my feeling these "clocks" capture different things at different moments of life time

Need to do similar in my case too :-)

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albedo's Photo albedo 30 Aug 2022

... sorry, also good if I catch it well:

- Horvath clock focus on cells

- Hannum clock focus on immune

- DudeninPACE on speed of aging

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Michael Lustgarten's Photo Michael Lustgarten 30 Aug 2022

... sorry, also good if I catch it well:

- Horvath clock focus on cells

- Hannum clock focus on immune

- DudeninPACE on speed of aging

 

Yes, but they each have particular strengths-Horvath for its correlation with chronological age, Hannum as a marker of immune system aging, and DunedinPACE as the only measure that was able to detect a reduced epigenetic as a resut of CR in people.

I'm not sure about 0.6 being different from 0.8, but I intend on retesting many times, and with enough data I should be able to see what may further reduce it.


Edited by Michael Lustgarten, 30 August 2022 - 12:32 PM.
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