November 2022 Longevity Review
Chris Pollyanna
08 Dec 2022
Apart from the first results of my n=1 rapamycin trial, this month you’ll find senolytics for skincare and rapamycin for IVF treatment among the highlights, along with why natural remedies aren’t necessarily better than pharmaceuticals and a rather simple solution to reduce cognitive decline for those with hearing loss.
In the supplemental section there is the suggestion that cellular enlargement is a potential new “Hallmark of Ageing”, as well as how much resistance exercise is needed for longevity and what the best time for exercise is. In addition, clinical NMN trials are coming in thick and fast now, with two more making an appearance this month. Of course, this is just scratching the surface!
Canadian Longevity Association
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CLA News
Finally a little bit of news from the CLA: we had a small dinner to celebrate our one year anniversary of incorporation at the Amsterdam Brewery in Toronto. I only organised it at the last minute, so many people already had other plans, but for those who came, the stimulating discussion stretched late into the night.
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johnhemming
08 Dec 2022
Thanks for publishing your levine results I find it useful to think about the mechanisms with these.
As far as HbA1c goes you do need to be careful about exactly how this is tested. Some labs use tests which pick up the labile form of HbA1c (sometimes called HbA1d) that can give a false positive of being pre-diabetic.
I think the immunoflourescent tests can distinguish more effectively between the two types of glycated haemoglobin.
What this means is that some labs
a) Give a higher value
b) Have a higher value for samples when the blood has waited a while before being tested.
