Homomatrix
maestro949 26 Mar 2007
Product description from the company website...
Curidium has developed a research platform that combines and integrates target discovery research with clinical data, to determine the underlying disease mechanisms or "molecular signatures" of disease. Known as Homomatrix® , the technology has adopted principles of genetics, molecular pharmacology and epidemiology to analyse biological data from disease and control patients.
Schematic representation of the application of Homomatrix:
(IP: Intellectual Property to Curidium / ID: Identification)
Curidium applies Homomatrix® to either gene (mRNA) expression data or protein activity measurements derived from any gene, protein or pharmacologically tractable target. It is a systematic process, allowing a gene or protein to be analysed and characterised as contributing to a potential disease mechanism.
On a genome-wide scale (e.g. using gene-expression microarrays), Homomatrix® is applied to identify underlying disease mechanisms, including signalling pathways and potentially novel gene-gene associations. The combined findings, covering the whole or a large part of the human genome, segregate the patient population studied into subgroups, each with a distinct molecular signature. Although the method has strong bioinformatics and biostatistics components, its uniqueness stems from a collection of proprietary pattern recognition tools and specific sequences of mathematical algorithms and statistical methods used to analyse human biological data.
Complemented by extensive know-how developed within Curidium, Homomatrix® is operated and managed in house, in support of target discovery, diagnostic and clinical development for internal programmes and planned customised collaborations with corporate partners.
Link to Company Website
maestro949 26 Mar 2007
SIRS Lab - Gene Expression Service
It'll be interesting to watch the costs of these services. I suspect at some point the informatics analysis will be something we can find or develop software for.
Edited by maestro949, 28 September 2007 - 08:22 PM.