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A t-res cap between cheek and gum?

sUper GeNius's Photo sUper GeNius 29 Apr 2007

Although I have read there is definitely a question of bioavailibility of t-res, I have also read that there is *no* question that the digestive track is getting saturated with t-res, and thus our risks of colon and stomach cancers may be lessened. But what about the other end, our mouths and throats?

I have a few Longevinex caps leftover, and now, every other day, I bite open a capsule and swish the liquid contents around abit before washing down with some liquid.

Sound like a good idea?
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tintinet's Photo tintinet 29 Apr 2007

What's it taste like?

Might enhance absorption, I suppose. Might be better mixed with lipid (perhaps EVOO?)
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sUper GeNius's Photo sUper GeNius 29 Apr 2007

What's it taste like?

Might enhance absorption, I suppose. Might be better mixed with lipid (perhaps EVOO?)


The taste is hard to describe. Not too bad. I am not trying to enhance absolution. Simply bathing the oral tissues and throat with the t-res.
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proteomist's Photo proteomist 29 Apr 2007

Resveratrol is really poorly soluble in vegetable oil. It is however, very soluble in 30-50% ethanol. If you were to dissolve some in 80-100 proof vodka and gargle with it for about thirty seconds, you might accomplish some systemic absorption and also saturation of the oral tissue in one go. Plus your teeth would be nicely clean.

Tintinet: On a technical note, it doesn't go into EVOO even if you acetylate it. Kind of surprising, I thought.


What's it taste like?

Might enhance absorption, I suppose. Might be better mixed with lipid (perhaps EVOO?)


The taste is hard to describe. Not too bad. I am not trying to enhance absolution. Simply bathing the oral tissues and throat with the t-res.

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sUper GeNius's Photo sUper GeNius 29 Apr 2007

Resveratrol is really poorly soluble in vegetable oil. It is however, very soluble in 30-50% ethanol. If you were to dissolve some in 80-100 proof vodka and gargle with it for about thirty seconds, you might accomplish some systemic absorption and also saturation of the oral tissue in one go. Plus your teeth would be nicely clean.

Tintinet: On a technical note, it doesn't go into EVOO even if you acetylate it. Kind of surprising, I thought.


What's it taste like?

Might enhance absorption, I suppose. Might be better mixed with lipid (perhaps EVOO?)


The taste is hard to describe. Not too bad. I am not trying to enhance absolution. Simply bathing the oral tissues and throat with the t-res.


Doesn't lecithin aid absorption?
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proteomist's Photo proteomist 30 Apr 2007

Generally speaking, the presence of a soluble, hydrophobic carrier would certainly help with absorption in the gut. Probably most any food item will do or this. I've found that when adding pure resvertrol powder to a blended smoothie (whey powder, banana, yogurt typically), I get much greater dissolution than when I add it to water. In fact you can see the drink take on a light red color cast, which is indicative of dissolved resveratrol.

For the purpose he desires however, we're talking about an exposure time of probably less than a minute, so the resveratrol should probably be directly solubilized in order to ensure maximal contact with cell membranes in the mouth.
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tintinet's Photo tintinet 30 Apr 2007

Generally speaking, the presence of a soluble, hydrophobic carrier would certainly help with absorption in the gut. Probably most any food item will do or this. I've found that when adding pure resvertrol powder to a blended smoothie (whey powder, banana, yogurt typically), I get much greater dissolution than when I add it to water. In fact you can see the drink take on a light red color cast, which is indicative of dissolved resveratrol.

For the purpose he desires however, we're talking about an exposure time of probably less than a minute, so the resveratrol should probably be directly solubilized in order to ensure maximal contact with cell membranes in the mouth.



Really? The drink turns light red? I'm assuming the pure resv. powder you're using is pure white before blending, no?
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proteomist's Photo proteomist 30 Apr 2007

The powder is quite white, but not completely devoid of color. By MS it is very pure.

It actually turns rather dark red, as if I'd blended in a few strawberries. At first I thought it was some weird oxidation reaction going on and was somewhat worried, but after seeing that resveratrol gives a redish cast on dissolution in polar protic solvents, I figure it's the resveratrol. Strictly speaking it could be some contaminant with a very high UV/blue extinction coefficient, I guess, rather than resveratrol.

You know, I have a few grams of completely pure synthetic material (I have samples of just about every bulk product now, it seems [lol]). I'll give that a side by side comparison the next time I blend up some fruit.
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sUper GeNius's Photo sUper GeNius 02 May 2007

The powder is quite white, but not completely devoid of color. By MS it is very pure.

It actually turns rather dark red, as if I'd blended in a few strawberries. At first I thought it was some weird oxidation reaction going on and was somewhat worried, but after seeing that resveratrol gives a redish cast on dissolution in polar protic solvents, I figure it's the resveratrol. Strictly speaking it could be some contaminant with a very high UV/blue extinction coefficient, I guess,  rather than resveratrol.

You know, I have a few grams of completely pure synthetic material (I have samples of just about every bulk product now, it seems [lol]). I'll give that a side by side comparison the next time I blend up some fruit.


I used a household cleaner that contains bleach to clean my kitchen counter, and I noticed a bright red color. I wondered what had happened until I read your post. I suspected there were a few grains of t-res on the counter, even though I hadn't seen any. So I cracked open a capsule of Country Life and tried it. It turns the powder bright blood red! I wondered whether it was the emodin, so I tried AOR t-res. This product can't have much/any emodin, since the capsules are half the size of the Country Life, yet have the same 100mg of t-res. Again, a bright blood red!

Try it yourself!
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health_nutty's Photo health_nutty 02 May 2007

Yes, I'm taking all my resveratrol powder in a drink so I'm getting this effect every time :)
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tintinet's Photo tintinet 02 May 2007

The powder is quite white, but not completely devoid of color. By MS it is very pure.

It actually turns rather dark red, as if I'd blended in a few strawberries. At first I thought it was some weird oxidation reaction going on and was somewhat worried, but after seeing that resveratrol gives a redish cast on dissolution in polar protic solvents, I figure it's the resveratrol. Strictly speaking it could be some contaminant with a very high UV/blue extinction coefficient, I guess,  rather than resveratrol.

You know, I have a few grams of completely pure synthetic material (I have samples of just about every bulk product now, it seems [lol]). I'll give that a side by side comparison the next time I blend up some fruit.


I used a household cleaner that contains bleach to clean my kitchen counter, and I noticed a bright red color. I wondered what had happened until I read your post. I suspected there were a few grains of t-res on the counter, even though I hadn't seen any. So I cracked open a capsule of Country Life and tried it. It turns the powder bright blood red! I wondered whether it was the emodin, so I tried AOR t-res. This product can't have much/any emodin, since the capsules are half the size of the Country Life, yet have the same 100mg of t-res. Again, a bright blood red!

Try it yourself!


Why did you think it might be emodin? proteomist stated he was seeing the red with t-resveratrol "very pure" "By MS."
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sUper GeNius's Photo sUper GeNius 11 May 2007

Even more reason someone should develop a t-res gargle:

http://www.theregist...terrible_price/
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Anthony_Loera's Photo Anthony_Loera 11 May 2007

tobar8,

I actually laughed out loud an that one...
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