AICAR
edward 26 Aug 2008
Anyways this stuff is like something out of an endurance athlete's wildest dream.
44% improvement in endurance over controls with no training, 70% improvement over controls with training. Converts muscle fibers to lean mean fat burning machines (might not be so great if you were trying to build fast twitch muscle fiber, but then again I'd rather have the biology of a world class endurance athlete with half the effort than a third class strength athlete working twice as hard)
http://www.latimes.c...0,4249687.story
insulin sensitization
http://www.sciencedi...46a5f1545367f84
http://www.webmd.com...in-a-pill-maybe
It is insanely expensive right now as it is only marketed toward researchers at "rat dosages".
Shepard 26 Aug 2008
edward 26 Aug 2008
Ehhh... metformin has some problems, testosterone lowering effect, increase in circulating TNF-alpha, gastrointestinal side effects. Low carb, of course, I live in low carb land, but I am an American after all with that inborn desire to solve everything with a pill
Shepard 26 Aug 2008
Ehhh... metformin has some problems, testosterone lowering effect, increase in circulating TNF-alpha, gastrointestinal side effects.
Finally, someone that agrees with me.
Although, a couple of our members didn't seem to have any trouble with testosterone or SHBG from metformin when I asked them.
neogenic 26 Aug 2008
There is a whole thread on this, not in this section. I've looked the research on AICAR for 3 years now, prior to even these studies...I used to wonder if there was any potential in humans until this batch of studies came out. I too have looked for the chemical and the prices are insanity...though cheaper than they were a few years ago from the chem. houses. There's a number of compounds I thought about exploitng in this pathway actually and some supplements I am designing are along this train of thought.I searched to see if someone had started a topic on this and apparently they hadn't, unless its hiding somewhere.
Anyways this stuff is like something out of an endurance athlete's wildest dream.
44% improvement in endurance over controls with no training, 70% improvement over controls with training. Converts muscle fibers to lean mean fat burning machines (might not be so great if you were trying to build fast twitch muscle fiber, but then again I'd rather have the biology of a world class endurance athlete with half the effort than a third class strength athlete working twice as hard)
http://www.latimes.c...0,4249687.story
insulin sensitization
http://www.sciencedi...46a5f1545367f84
http://www.webmd.com...in-a-pill-maybe
It is insanely expensive right now as it is only marketed toward researchers at "rat dosages".
http://www.imminst.o...o...c=23495&hl=
edward 27 Aug 2008
neogenic 28 Aug 2008
Agreed. I searched here originally and started a thread on it. My thread got collapsed in to that one. I rarely stray outside of the supplements forum. And we all know how effective the search is here. I wish that could be fixed. There'd be so much more posting and better threads if it was. There'd be less of the "top 10 supplement" threads and whatever started over and over. You can't criticize anyone about not searching...it just is nearly useless.Thanks for pointing out that other thread, I think the search function was having issues when I looked for it before, anyway its a good topic for the supplements section
Mind 28 Aug 2008
Also, if you go to "more search options" and then use combinations of words (Example: "+nanotech +cancer") along with a member name, you will get better results, not great but better.