LONGECITY

Sounds good !

Doses of vitamin B1 (thiamine) can reverse early kidney disease in people with type 2 diabetes, research shows.

http://news.bbc.co.u...lth/7796073.stm

I'm a little confused as to how exactly they believe the thiamine is helping. It says they think it's due to protection of blood vessels against the effects of hyperglycemia; in this vein (er, pun not intended) they are referring to the same rationale by which people here take benfotiamine-- AGE breaker and protective of blood vessels. I know taking high doses of thiamine reportedly works similar to sulbutiamine, but I didn't know if that applied to benfotiamine too. I guess I never quite got the B1 story straight.

Alternatively, the article initial sites a reduction of albumin in the urine; I might be wrong, but I thought that protein in the urine was a sign that the glomureli were taking some serious damage and becoming "leaky"; but then again, they didn't teach nephrology in much detail in my medic class. Is the reduction in albuminuria merely an indicator of reversing damage?

This is good news. I rotate in a diabetes hospital that serves the very, very poor community. I can try to implement this in their treatment protocol. Usually, it's dangerous to give high doses of anything when the kidneys fail but these people have no other options. Dialysis is one but most cannot afford so the only REAL option is to go home and prey. Yeah...

http://news.bbc.co.u...lth/6935482.stm

Previous study regarding Thiamine defficiency with Diabetes 1/2



"Thiamine is key to warding off vascular problems such as kidney, retina and nerve damage as well as heart disease and stroke. It works by helping protect cells against the effect of high glucose levels. "

Thanks for the link, youandme

Does anyone here currently take vitamin B-1, (thiamine), sulbutiamine, and benfotiamine daily as part of their regimen?

I take vitamin B-1 and benfotiamine on a regular basis however I've yet to try sulbutiamine but am considering adding it to my stack.

- pycnogenol
Edited by pycnogenol, 04 January 2009 - 03:15 PM.

Thanks for the link, youandme

Does anyone here currently take vitamin B-1, (thiamine), sulbutiamine, and benfotiamine daily as part of their regimen?

I take vitamin B-1 and benfotiamine on a regular basis however I've yet to try sulbutiamine but am considering adding it to my stack.

- pycnogenol

I take 200mg sulbutiamine, 300mg benfotiamine daily and only 25 mg thiamine in a b-complex.

I added the sulbutiamine recently, because the brain needs B1 to protect against hyperglycemia,
and benfotiamine does not cross the BBB.

Thanks for the link, youandme

Does anyone here currently take vitamin B-1, (thiamine), sulbutiamine, and benfotiamine daily as part of their regimen?

I take vitamin B-1 and benfotiamine on a regular basis however I've yet to try sulbutiamine but am considering adding it to my stack.

- pycnogenol

I take 200mg sulbutiamine, 300mg benfotiamine daily and only 25 mg thiamine in a b-complex.

I added the sulbutiamine recently, because the brain needs B1 to protect against hyperglycemia,
and benfotiamine does not cross the BBB.

What vendor do you get your sulbutiamine from?

Thanks for the link, youandme

Does anyone here currently take vitamin B-1, (thiamine), sulbutiamine, and benfotiamine daily as part of their regimen?

I take vitamin B-1 and benfotiamine on a regular basis however I've yet to try sulbutiamine but am considering adding it to my stack.

- pycnogenol

I take 200mg sulbutiamine, 300mg benfotiamine daily and only 25 mg thiamine in a b-complex.

I added the sulbutiamine recently, because the brain needs B1 to protect against hyperglycemia,
and benfotiamine does not cross the BBB.

What vendor do you get your sulbutiamine from?

I get it from relentless improvement.

other good news that I've seen...

thiamine and greater mental acuity?

see attachment  thiaminefulltext.pdf   110.7KB   149 downloads

Being water soluble, the body excretes excess B1 so it seems there is a lesser chance of negative side effects than from other supplements. Anyone know of any negative side effects of B1 supplementation?

Being water soluble, the body excretes excess B1 so it seems there is a lesser chance of negative side effects than from other supplements. Anyone know of any negative side effects of B1 supplementation?

800mg of sulbutiamine made me feel sick. This was back when I was trying to use it as a nootropic.
Although I suspect you're looking for more long term side effects ...
Edited by rwac, 04 January 2009 - 06:48 PM.

Being water soluble, the body excretes excess B1 so it seems there is a lesser chance of negative side effects than from other supplements. Anyone know of any negative side effects of B1 supplementation?

From Mayo Clinic: http://www.mayoclini...DDA8B9C4F9C3A24



Side Effects and Warnings Thiamin is generally considered safe and relatively nontoxic, even at high doses. No clear tolerable upper level (UL) of intake has been established. Dermatitis or more serious hypersensitivity reactions occur rarely.

Large doses may cause drowsiness or muscle relaxation.

Injections of thiamin may cause burning. Reactions can often be avoided by slow administration into larger veins.





Allergies Rare hypersensitivity/allergic reactions have occurred with thiamin supplementation. A small number of life-threatening anaphylactic reactions have been observed with large parenteral (intravenous, intramuscular, subcutaneous) doses of thiamin, generally after multiple doses.

Skin irritation, burning, or itching may rarely occur at injection sites.

Contact dermatitis may occur with occupational exposure and may cause sensitization and lead to dermatitis-type reactions after subsequent oral or injected administrations.

I'm currently using sulbutiamine, fursultiamine (TTFD) in pill and cream and benfotiamine. So far I've noticed a reduction in orthostatic hypotension, vertigo and tremors. The sulbutiamine is finally giving me a good boost. Better yet, the country I'm living in now sells Arcalion, the pharmaceutical version of it. Good stuff I tell ya.

I'm currently using sulbutiamine, fursultiamine (TTFD) in pill and cream and benfotiamine. So far I've noticed a reduction in orthostatic hypotension, vertigo and tremors. The sulbutiamine is finally giving me a good boost. Better yet, the country I'm living in now sells Arcalion, the pharmaceutical version of it. Good stuff I tell ya.

Lufega, where do you get the fursultiamine from ?

Lufega, where do you get the fursultiamine from ?

I get the pills here https://www.emersone.../PID-ALLI2.aspx

The cream, which also has methyl-B12 you can buy in many places including Amazon.com. Search for "Authia cream"

I'm going to increase the dose on everything. I used 900 mg benfotiamine for 1 month and it eliminated my essential tremor completely. After about 2 weeks of not using it, it slowly returned. Maybe the TTFD will have a similiar effect at higher doses.
Edited by Lufega, 05 January 2009 - 03:02 PM.

Lufega, where do you get the fursultiamine from ?

I get the pills here https://www.emersone.../PID-ALLI2.aspx

The cream, which also has methyl-B12 you can buy in many places including Amazon.com. Search for "Authia cream"

I'm going to increase the dose on everything. I used 900 mg benfotiamine for 1 month and it eliminated my essential tremor completely. After about 2 weeks of not using it, it slowly returned. Maybe the TTFD will have a similiar effect at higher doses.

You convinced me. I will try the TTFD.
What dosage do you use ?

Lufega, where do you get the fursultiamine from ?

I get the pills here https://www.emersone.../PID-ALLI2.aspx

The cream, which also has methyl-B12 you can buy in many places including Amazon.com. Search for "Authia cream"

I'm going to increase the dose on everything. I used 900 mg benfotiamine for 1 month and it eliminated my essential tremor completely. After about 2 weeks of not using it, it slowly returned. Maybe the TTFD will have a similiar effect at higher doses.

You convinced me. I will try the TTFD.
What dosage do you use ?

I use one pill per day of whatever the dose it. TTFD crosses the BBB. I also apply the cream at night. I use a dime size portion. My blood tests came back, my B12 is off the charts! I've also been using sublingual B12..this stuff is really effective!

I use one pill per day of whatever the dose it. TTFD crosses the BBB. I also apply the cream at night. I use a dime size portion. My blood tests came back, my B12 is off the charts! I've also been using sublingual B12..this stuff is really effective!

I've been using the TTFD for a few weeks, and it seems to work well.
I can now feel the effects of sulbutiamine.
I think I'll just stick to the oral stuff for now.