Found a dosing schedule to minimize "l...
health_nutty 02 Jun 2010
Previously I was taking 10mg in the morning and 10mg at night (with brain fog in the morning).
1) 5mg in the morning (no brain fog)
2) 15mg at night (this works better for my morning anxiety/mood).
Anyone else having trouble may just want to dose at bedtime or split the dose to be 75% bedtime and 25% morning
meursault 02 Jun 2010
If I take too much lithium, I get a bit of brain fog. I've found a dosing schedule that really minimizes this. Lithium has done wonders for my mood and axienty (especially morning anxiety and mood).
Previously I was taking 10mg in the morning and 10mg at night (with brain fog in the morning).
1) 5mg in the morning (no brain fog)
2) 15mg at night (this works better for my morning anxiety/mood).
Anyone else having trouble may just want to dose at bedtime or split the dose to be 75% bedtime and 25% morning
I've noticed that taking 1.25 mg of elemental lithium 90 minutes before bed followed by pomegranate extract 30-45 minutes later significantly decreases my need for sleep (with this I've slept about 30 minutes less than usual for the past 3 days that I've tried this).
health_nutty 02 Jun 2010
I've noticed that taking 1.25 mg of elemental lithium 90 minutes before bed followed by pomegranate extract 30-45 minutes later significantly decreases my need for sleep (with this I've slept about 30 minutes less than usual for the past 3 days that I've tried this).
Have you tried the two seperately?
bacopa 02 Jun 2010
health_nutty 02 Jun 2010
that lithium fog crippled me and still is bothersome for the past week. I was at 1200mg dose obviously of carbonate form, and it was terrible. The fact that you got that on a tiny dose is very telling.
Some people get it from as little as 5mg of elemental lithium.
I'm just doing the math:
1200mg of carbonate is 480mg of elemental lithium. Orotate is 3 times more bioavaible in rats. So my 20mg dose MAY be more like 60mg from carbonate. Still nowhere near the 480mg you are taking...wow I can only imagine.
Edited by health_nutty, 02 June 2010 - 11:19 PM.
bacopa 03 Jun 2010
Edited by dfowler, 03 June 2010 - 12:33 AM.
Lauren 03 Jun 2010
I had also taken lithium for my bipolar symptoms, and it too had locked me into a perpetual brain fog. Unfortunately, this had merely exacerbated my own fog which I had been experiencing from psychosis, and that has persisted even to the present time. In fact, this brain fog has become such a pervasive mitigating factor that it has greatly depleted my abilities at formalistic cogitation.
But you truly do have a brilliant mind, Sweetie - Don't ever doubt that for a second.
I'm getting off that stuff, as I have a fragile, for lack of better word, brain, and I'm hoping that it is just the lithium, cause I've had fog before from psychosis...so this may have triggered another fog, but I'll only know if I get off it.
Edited by Lauren, 03 June 2010 - 03:24 AM.
health_nutty 03 Jun 2010
I'm getting off that stuff, as I have a fragile, for lack of better word, brain, and I'm hoping that it is just the lithium, cause I've had fog before from psychosis...so this may have triggered another fog, but I'll only know if I get off it.
Why don't you adjust the dosage instead of getting off of it completely? It shouldn't be all or nothing. 1200mg is the higher end of the "Therapeutic" range (from 300mg-1200 mg of lithium carbonate).
meursault 03 Jun 2010
I've noticed that taking 1.25 mg of elemental lithium 90 minutes before bed followed by pomegranate extract 30-45 minutes later significantly decreases my need for sleep (with this I've slept about 30 minutes less than usual for the past 3 days that I've tried this).
Have you tried the two seperately?
Yes. This combination is continuing to work for me.
HiQ 04 Jun 2010
However, what I did find, was that around 2 days after the dose, the brain fog was relieved. During that day, I actually felt more focused and aware than usual. From this, I gather that I must be quite sensitive to lithium. From what I have seen, many people take anywhere from 10-20mg of elemental lithium from lithium orotate. I will keep using it, but on a decreased dosage (around 1.5mg elemental). But I may try the dosing schedule you suggest.
Oh, and the brain fog does go away (well it did for me anyway). You just need to give it a few days.
aaron_e 04 Jun 2010
http://circadiana.bl...nd-bipolar.html
chrono 04 Jun 2010
Very interesting blog post, as well!
Awesome! Did you discontinue your dose all at once?yay the fog went away finally I feel human again
I'd also encourage you to think about a much smaller dose. I found one paper so far (mouse study) that suggests some neuroprotection is present at low dosages. Though I don't think any studies have been done concerning the more dramatic effects like gray matter generation.
Edited by chrono, 06 June 2010 - 12:44 PM.
chrono 22 Jul 2010
But even with this 1-4 dosing schedule, I found that later in the day I was getting a little brain fog, and feeling more emotionally restricted and sedate. I felt best for the first part of the day, like it was improving my mood in "rebound" more than by working directly due to a certain serum level.
For the past 3 weeks, I've just been taking 5mg at night. After switching to this schedule, I found this improved mood to last for most of the day (mostly anxiolysis and improved stress response, but also a general brightening of mood), while brain fog was eliminated completely.
Wondering if anyone else has tried this night-only dosing?
Edited by chrono, 28 October 2010 - 10:29 AM.
forgot a word!
rwac 22 Jul 2010
Wondering if anyone else has tried this night-only dosing?
5mg/day at night works great for me.
Doesn't lithium have a fairly long half life ?
chrono 22 Jul 2010
pycnogenol 22 Jul 2010
5mg/day at night works great for me.
Doesn't lithium have a fairly long half life ?
5mg/day at noon works great for me.
rwac - do you cycle it? I don't (well, not yet anyway).
I think (not totally sure though) that it does have a fairly long half-life.
Lithium and brain health article:
http://www.life-enha...late.asp?id=952
rwac 22 Jul 2010
rwac - do you cycle it? I don't (well, not yet anyway).
I think (not totally sure though) that it does have a fairly long half-life.
I don't cycle it. All the data I can find says that the half life is about 12-24 hrs, but I find the effects wearing off after 3-4 days.
chrono 23 Jul 2010
Lauren 18 Sep 2010
yay the fog went away finally I feel human again
That's awesome, Sweetie!! I'm so relieved to hear that you discontinued use of the lithium. I myself just discontinued use of lithium for my bipolar symptoms, and I think with such greater clarity now. I'm so glad to hear that you're doing so much better!! I love you *hugs*
Thorsten3 27 Oct 2010
yay the fog went away finally I feel human again
That's awesome, Sweetie!! I'm so relieved to hear that you discontinued use of the lithium. I myself just discontinued use of lithium for my bipolar symptoms, and I think with such greater clarity now. I'm so glad to hear that you're doing so much better!! I love you *hugs*
LOL You don't get posts like this everyday from fellow forum members...
Does anybody know if it would be a good idea to supplement inositol with lithium orotate. I saw it mentioned earlier in this thread that lithium depletes inositol from the cells - Maybe they would compliment each other?
Also there are very few anecdotal accounts on here. That's my biggest gripe of most of the material on this site. People seem obsessed by studies and literature but very few people say how it is helping them. I appreciate the former is vital for sake of quality but personal accounts count for just as much when we are discussing topics such as this.
From what I have heard here, brain fog seems to be a fairly common effect. Not a lot I can really do with that information.
From what I have noticed so far is that it does seem to chill me out a bit. I'm only on 5mg orotate so may dose this chronically to see what the long term effects are. Maybe go up to 10mg or slightly higher to experiment with dosing as well.
Edited by Thorsten, 27 October 2010 - 03:00 PM.
health_nutty 27 Oct 2010
Does anybody know if it would be a good idea to supplement inositol with lithium orotate. I saw it mentioned earlier in this thread that lithium depletes inositol from the cells - Maybe they would compliment each other?
I take lecithin which takes care of my choline and inositol requirement. The brain fog I had initially at higher doses (of 20mg) went away.
Thorsten3 27 Oct 2010
Does anybody know if it would be a good idea to supplement inositol with lithium orotate. I saw it mentioned earlier in this thread that lithium depletes inositol from the cells - Maybe they would compliment each other?
I take lecithin which takes care of my choline and inositol requirement. The brain fog I had initially at higher doses (of 20mg) went away.
That's interesting to know, I was seriously considering not carrying on with it because of this annoying fog I have experienced already. My short term memory has gone to pot and my thought processes are a bit dissolved at present. Just out of interest what has lithium done for you? Positives, negatives?
health_nutty 28 Oct 2010
How long have you been on it? The brain fog went away after 3-4 weeks.
Sciolaro 28 Oct 2010
Lithium orotate has all but eliminated my anxiety and has helped with my mood a fair bit. It is also supposed to be good for neoroprotection. There is a study that showed that lithium is improves the effectiveness of antidepressents.
How long have you been on it? The brain fog went away after 3-4 weeks.
I've taken both orotate and aspartate regularly for about six months. I've never exceeded 20mg daily. I took 10mg before bed for a few months, and now I just take 5mg. I never experienced brain fog or any cognitive decline. I believe it has subdued my anxiety.
Just thought I'd toss my ticket in the hat.
Thorsten3 28 Oct 2010
Lithium orotate has all but eliminated my anxiety and has helped with my mood a fair bit. It is also supposed to be good for neoroprotection. There is a study that showed that lithium is improves the effectiveness of antidepressents.
How long have you been on it? The brain fog went away after 3-4 weeks.
I've taken both orotate and aspartate regularly for about six months. I've never exceeded 20mg daily. I took 10mg before bed for a few months, and now I just take 5mg. I never experienced brain fog or any cognitive decline. I believe it has subdued my anxiety.
Just thought I'd toss my ticket in the hat.
Great, thanks, that's encouraging.
Thorsten3 28 Oct 2010
Lithium orotate has all but eliminated my anxiety and has helped with my mood a fair bit. It is also supposed to be good for neoroprotection. There is a study that showed that lithium is improves the effectiveness of antidepressents.
How long have you been on it? The brain fog went away after 3-4 weeks.
Indeed I've heard of it being used to augment other types of medications. What types of medications would it be used alongside specifically? If you know this? I have tried searching for this information but unfortunately I came up short. I can see why they might do that as lithium on its own is not going to be a fun drug to be on. I've already noticed how it flatens me out somewhat (things that I'd normally find hilarious I'd now struggle to crack a smile at). Also the fog I have is not benefitting my cogntion that's for sure. On the positive side I feel more chilled and I think it is helping slightly with overactive thought processes.
I am also taking a cocktail of a few other supplements to try and neutralize this negative effect somehow and turn the gears up more slightly (idebenone, resveratrol,tmg, metafolin). Hopefully I can find a happy medium.
nito 28 Oct 2010
Lithium orotate has all but eliminated my anxiety and has helped with my mood a fair bit. It is also supposed to be good for neoroprotection. There is a study that showed that lithium is improves the effectiveness of antidepressents.
How long have you been on it? The brain fog went away after 3-4 weeks.
You mean i can take lithium orotate along side things like perika and serofin which are SJW without getting serotonin syndrome or things like that?
chrono 28 Oct 2010
I've had to re-titrate a couple of times over the last few months after forgetting to take it for a few days, and I've never just started at a full 5mg again.
health_nutty 28 Oct 2010
Indeed I've heard of it being used to augment other types of medications. What types of medications would it be used alongside specifically? If you know this? I have tried searching for this information but unfortunately I came up short.
You mean i can take lithium orotate along side things like perika and serofin which are SJW without getting serotonin syndrome or things like that?
http://www.mayoclini...ication/MY00639
It looks like it would synergize with SJW but the article talks about prescription anti-depressants.