Lemurs lose weight with resveratrol
VP.
24 Jun 2010
Fabienne Aujard, from the Centre National de la Recherche Scientifique, Paris, France, worked with a team of researchers to investigate the effect of dietary supplementation with resveratrol on the weight, metabolism and energy intake of six mouse lemurs.
She said, "The physiological benefits of resveratrol are currently under intensive investigation, with recent work suggesting that it could be a good candidate for the development of obesity therapies. We've found that lemurs eating a diet supplemented with the compound decreased their energy intake by 13% and increased their resting metabolic rate by 29%".
The researchers demonstrated that a four-week resveratrol supplementation was associated with a decrease in food intake and a reduction in seasonal body-mass gain. The response to resveratrol supplementation also involved significant changes in the animals' body temperatures. According to Dr Aujard, "These results provide novel information on the potential effects of resveratrol on energy metabolism and control of body mass in a primate".
http://www.physorg.c...s196402470.html
I am my lightest weight in 20 years. Res may have something to do with my weight.
She said, "The physiological benefits of resveratrol are currently under intensive investigation, with recent work suggesting that it could be a good candidate for the development of obesity therapies. We've found that lemurs eating a diet supplemented with the compound decreased their energy intake by 13% and increased their resting metabolic rate by 29%".
The researchers demonstrated that a four-week resveratrol supplementation was associated with a decrease in food intake and a reduction in seasonal body-mass gain. The response to resveratrol supplementation also involved significant changes in the animals' body temperatures. According to Dr Aujard, "These results provide novel information on the potential effects of resveratrol on energy metabolism and control of body mass in a primate".
http://www.physorg.c...s196402470.html
I am my lightest weight in 20 years. Res may have something to do with my weight.
unglued
24 Jun 2010
But the abstract says they used 200mg/kg/day. Unadjusted for species, that would be 16 grams per day for an 80kg human, which is much more than has been clinically tested for safety or that even the people in this forum have reported trying. (Anyone know the nominal lemur to human dosage adjustment?)
maxwatt
24 Jun 2010
But the abstract says they used 200mg/kg/day. Unadjusted for species, that would be 16 grams per day for an 80kg human, which is much more than has been clinically tested for safety or that even the people in this forum have reported trying. (Anyone know the nominal lemur to human dosage adjustment?)
According to the preliminary version of the paper ( available here) a mouse lemur typically weighs 4 grams. about the same as a mouse. Going on body mass alone and ignoring other metabolic parameters which may be equally impotant, that would put the human dose at something like 2 to 4 grams a day, which is achievable. Some of our posters can attest to weight loss or gain at this dose.
malbecman
24 Jun 2010
I've lost weight recently but also stepped up my aerobic exercise (more so than when I first started using resveratrol).
