Cholesterol and Dementia
lynx
29 Oct 2004
Ann Neurol. 2004 Oct 25;56(5):745-749 [Epub ahead of print] Related Articles, Links
Serum lipids and hippocampal volume: The link to Alzheimer's disease?
Wolf H, Hensel A, Arendt T, Kivipelto M, Winblad B, Gertz HJ.
Department of Psychiatry, University of Leipzig, Leipzig, Germany.
The association between hippocampal volume (as a presumed index of Alzheimer's disease pathology) with serum total cholesterol, high-density lipoprotein cholesterol, and low-density lipoprotein cholesterol was studied in 86 elderly subjects with a range of cognitive functions. High-density lipoprotein cholesterol, but not low-density lipoprotein cholesterol or total cholesterol, was associated with hippocampal volume and dementia. This is compatible with protective effects of high-density lipoprotein cholesterol on hippocampal atrophy and Alzheimer's disease. Ann Neurol 2004;56:745-749.
PMID: 15505826 [PubMed - as supplied by publisher]
Serum lipids and hippocampal volume: The link to Alzheimer's disease?
Wolf H, Hensel A, Arendt T, Kivipelto M, Winblad B, Gertz HJ.
Department of Psychiatry, University of Leipzig, Leipzig, Germany.
The association between hippocampal volume (as a presumed index of Alzheimer's disease pathology) with serum total cholesterol, high-density lipoprotein cholesterol, and low-density lipoprotein cholesterol was studied in 86 elderly subjects with a range of cognitive functions. High-density lipoprotein cholesterol, but not low-density lipoprotein cholesterol or total cholesterol, was associated with hippocampal volume and dementia. This is compatible with protective effects of high-density lipoprotein cholesterol on hippocampal atrophy and Alzheimer's disease. Ann Neurol 2004;56:745-749.
PMID: 15505826 [PubMed - as supplied by publisher]
scottl
29 Oct 2004
Lynx not sure if this fits in here, but I believe stress i.e. cortisol affects the hippocampus.
30 Oct 2004
Exercise remedies that, but failing that we've discussed supplements that may help reduce cortisol.
