LONGECITY

According to this study thiamine was best preserved with ascorbic acid in a refrigerator. Could the reason for sulbutiamines ineffectiveness be because it is highly unstable and depending on temperature, UV exposure it becomes worthless? This study seems to make that point clearly for thiamine which may be true also for sul. I read of a persons experience here mxr808 who bought it through United Pharmacies as Arcalion and had a great experience. So, I am thinking perhaps they have a formulation that preserves it better. Because depending on how they store this chemical it will be useless unless stored in refrigeration and with a preservative like ascorbic acid.

It's an interesting idea, but just looking at the structures, I doubt that thiamine and sulbutiamine share that many close physical properties:


Sulbutiamine



Thiamine


Degredation might be a problem (as it could be with any chemical), but I don't think we can assume it based on thiamine's properties. There seems to be a tendency for folks to assume that since it's a B1 analogue that effects/safety/properties are substantially similar, but even small modifications to a molecule can change all these things dramatically. And it looks like quite a few changes must be made to get from thiamine to sulbutiamine.

Besides, there are many reports (especially in the bodybuilding world) of sulbutiamine from non-pharmaceutical sources working well, so I think any ineffectiveness you've heard about is probably attributable to biochemical individuality.

Still, it probably wouldn't hurt to keep it in the fridge.
Edited by chrono, 28 October 2010 - 02:02 PM.

It's an interesting idea, but just looking at the structures, I doubt that thiamine and sulbutiamine share that many close physical properties:


Sulbutiamine



Thiamine


Degredation might be a problem (as it could be with any chemical), but I don't think we can assume it based on thiamine's properties. There seems to be a tendency for folks to assume that since it's a B1 analogue that effects/safety/properties are substantially similar, but even small modifications to a molecule can change all these things dramatically. And it looks like quite a few changes must be made to get from thiamine to sulbutiamine.

Besides, there are many reports (especially in the bodybuilding world) of sulbutiamine from non-pharmaceutical sources working well, so I think any ineffectiveness you've heard about is probably attributable to biochemical individuality.

Still, it probably wouldn't hurt to keep it in the fridge.

I called NutraPlantet and they told me that they keep it at around 70F and that the product has no additives. The guy I talked to took the product and it seemed like he was not too impressed with it although he did feel some energy. He did not sound very convincing to me. He also thinks that you build tolerance to it. He also said that it has a 2 year expiration date.

I also called CerebralHealth and they add no additives and it is suppose to keep for 2 to 3 years. The guy told me he is getting a fresh batch on Monday.So, I guess I am going to order some on Monday with some ascorbic acid and refrigerate it and see what happens. He thought it would be a good idea to get it with ascorbic acid. His cost is $65 for 100g and $29 for 100g of ascorbic acid. I am going to see if I can get just 30-50g.