Aniracetam: Half-life
unipolar_mania
23 Nov 2004
I read [1] that aniracetam weakly enhances AMPA activity and is rapidly metabolized. Does anyone know what is the half-life of aniracetam?
[1] AMPA receptor modulators as cognitive enhancers • REVIEW ARTICLE
Current Opinion in Pharmacology, Volume 4, Issue 1, February 2004, Pages 4-11
Gary Lynch
[1] AMPA receptor modulators as cognitive enhancers • REVIEW ARTICLE
Current Opinion in Pharmacology, Volume 4, Issue 1, February 2004, Pages 4-11
Gary Lynch
unipolar_mania
23 Nov 2004
In rats the half-life is 1.7-2.1 hours. What about humans?
J Pharm Sci. 1998 May;87(5):594-8. Pharmacokinetics of aniracetam and its metabolites in rats. Ogiso T, Iwaki M, Tanino T, Ikeda K, Paku T, Horibe Y, Suzuki H.
J Pharm Sci. 1998 May;87(5):594-8. Pharmacokinetics of aniracetam and its metabolites in rats. Ogiso T, Iwaki M, Tanino T, Ikeda K, Paku T, Horibe Y, Suzuki H.
nootropi
23 Nov 2004
I am not sure. But I suggest that you take 2 750 milligram doses twice daily, if that is the only racetam you are currently taking. And of course, take a choline source.
magr
23 Nov 2004
I am not sure. But I suggest that you take 2 750 milligram doses twice daily, if that is the only racetam you are currently taking. And of course, take a choline source.
Is that 2 X 750mg = 1500mg or 2 X 2 X 750mg = 3000mg?
Edited by magr, 23 November 2004 - 11:36 AM.
nootropi
23 Nov 2004
No; I meant 2 750 milligrams doses; that is, 750 milligrams twice daily, for a total of 1500 milligrams per day.
gulasch
24 Nov 2004
I have read somewhere that the half life is about 5 hours, but do not know where.
