Wrinkle Minimization
orangish 03 Apr 2011
Right now, I am 25. Some wrinkles are becoming visible and I'd like to minimize them before they get worse. Apart from occasional excess carbohydrates, my diet is fairly decent. I make sure to use high SPF sunscreen.
What might I do/use that would be effective on slightly visible wrinkles?
niner 04 Apr 2011
lunarsolarpower 05 Apr 2011
Reversal: botox (requires frequent reapplication though).
VidX 14 Apr 2011
Edited by VidX, 14 April 2011 - 01:01 PM.
mustardseed41 14 Apr 2011
any comments on this DYI serum: http://www.skincaret...nt-sources.html
Many swear it works for them.
Stefanovic 14 Apr 2011
any comments on this DYI serum: http://www.skincaret...nt-sources.html
Many swear it works for them.
But do you think the combo of those ingredients could actually make a huge difference?
orangish 20 Jun 2011
1. My sunscreen is neutrogena spf 80. It is several years old. Should this matter?
2. Apart from retinoids, is there anything that I can do that's low cost? I made a vitamin c serum, but I don't find this to be working that well.
VesperLynd 26 Jun 2011
To be honest, in the current economic environment, the price of Botox has dropped substantially.
VL
niner 26 Jun 2011
Yes. If it is several years old and it is still not used up, you are using WAY too little, or you are using it too infrequently, or both. As far as shelf life goes, I dunno. It's probably better than nothing. Might be fine.My sunscreen is neutrogena spf 80. It is several years old. Should this matter?
curious_sle 26 Jun 2011
nupi 27 Jun 2011
curious_sle 29 Jun 2011
um, i think it is a different product... yeah i think they also commercialized that special apple thingy that i don't buy into but thanks for the info.
orangish 29 Jun 2011
What are the side effects of retinoids?
mustardseed41 29 Jun 2011
Do i have to see a dermatologist to get a prescription for retinoids? I imagine I have to pay for this myself.
What are the side effects of retinoids?
https://www.alldaych...448__Tretinoin-
http://www.skinacea....t-part-one.html
Don't laugh at the super low prices. Trusted source used by many many people. Buy in bulk to help offset the $25 shipping fee.
Edited by mustardseed41, 29 June 2011 - 11:08 PM.
maxwatt 30 Jun 2011
http://www.freepaten...06/0188866.html
Long-Term Administration of diaminophenothiazines Improve Skin Elasticity and Activity Levels in Patients over 50.
A double blind, randomized, vehicle controlled study is conducted in 160 subjects ranging in ages from 50 to 65. Treatment groups are prescribed 25 µg diaminophenothiazine (azure A, azure B, azure C, thionine, toluidine blue, methylene blue, new methylene blue, or 1-9-dimethyl methylene blue) tablets taken orally with meals 3 times daily. Clinical monitoring, subjective self assessment, objective measurement methods of skin elasticity, epidermal hydration and skin surface lipids are used to determine effects of each treatment at four visits during 24 weeks. Clinical monitoring includes wrinkle counts, measurement of wrinkle depth around the right eye, and nasolabial fold depth. Results demonstrate consistent efficacy of diaminophenothiazine treatment over placebo in counteracting different signs of aging in the skin and improving overall energy levels.
Spectre 03 Jul 2011
Methylene blue administered orally is patented for wrinkle reduction and increasing energy levels in old people. In Atamna and Ames patent (Example 5) they fed 25 µg methylene blue trice a day to aged humans.
http://www.freepaten...06/0188866.htmlLong-Term Administration of diaminophenothiazines Improve Skin Elasticity and Activity Levels in Patients over 50.
A double blind, randomized, vehicle controlled study is conducted in 160 subjects ranging in ages from 50 to 65. Treatment groups are prescribed 25 µg diaminophenothiazine (azure A, azure B, azure C, thionine, toluidine blue, methylene blue, new methylene blue, or 1-9-dimethyl methylene blue) tablets taken orally with meals 3 times daily. Clinical monitoring, subjective self assessment, objective measurement methods of skin elasticity, epidermal hydration and skin surface lipids are used to determine effects of each treatment at four visits during 24 weeks. Clinical monitoring includes wrinkle counts, measurement of wrinkle depth around the right eye, and nasolabial fold depth. Results demonstrate consistent efficacy of diaminophenothiazine treatment over placebo in counteracting different signs of aging in the skin and improving overall energy levels.
This is awesome, I'm curious to know if taking Methylene Blue is a good idea for myself, being that I'm only 21 (I just started taking MB over the past 3 days and so far I'm enjoying the effects). What are the life-extending properties of Methylene Blue and how safe is it to be taking it at this age? Thanks.
Logan 03 Jul 2011
I've thought about taking methylene blue for many reasons, but I take SSRIs and a small amount of lithium everyday.
maxwatt 03 Jul 2011
Max, do you take methylene blue? If so, how much?
I've thought about taking methylene blue for many reasons, but I take SSRIs and a small amount of lithium everyday.
Yes, I take methylene blue, 60 mcg twice or thrice a day (if I remember the evening dose, and likewise for the afternoon dose.) I have a solution with an applicator for a precise dose, which I had made up to my spec by Kingherbs.
@Spectre asked:
This is awesome, I'm curious to know if taking Methylene Blue is a good idea for myself, being that I'm only 21 (I just started taking MB over the past 3 days and so far I'm enjoying the effects). What are the life-extending properties of Methylene Blue and how safe is it to be taking it at this age? Thanks.
No one knows the answers to your questions, for sure. I doubt there is a reason not to take it, but life-extension would take a long test period to be certain. I believe it does improve mitochondrial function even at your age, and might prevent ongoing damage and keep you youthful longer. But this is far from proven.
niner 03 Jul 2011
If you're worried about MAO inhibition, that isn't going to happen at the nanomolar doses of MB we're talking about here.I've thought about taking methylene blue for many reasons, but I take SSRIs and a small amount of lithium everyday.
Logan 04 Jul 2011
If you're worried about MAO inhibition, that isn't going to happen at the nanomolar doses of MB we're talking about here.I've thought about taking methylene blue for many reasons, but I take SSRIs and a small amount of lithium everyday.
Yeah I didn't think so. I take curcumin and have no problems with that. Thanks niner.
Logan 04 Jul 2011
Yes, I take methylene blue, 60 mcg twice or thrice a day (if I remember the evening dose, and likewise for the afternoon dose.) I have a solution with an applicator for a precise dose, which I had made up to my spec by Kingherbs.
What effects have you noticed, if any?
maxwatt 04 Jul 2011
Yes, I take methylene blue, 60 mcg twice or thrice a day (if I remember the evening dose, and likewise for the afternoon dose.) I have a solution with an applicator for a precise dose, which I had made up to my spec by Kingherbs.
What effects have you noticed, if any?
Possibly increased endurance and power output, mental clarity. Or else it's a placebo effect. Or maybe due to use of luteolin.
Metrodorus 24 Dec 2011
Any thoughts? Guinea pigs?
niner 25 Dec 2011
Danail Bulgaria 25 Dec 2011
I am making a clinical and I tried to start an online trail about the wrinkle healing medications. In case You decide to start taking something to heal Your wrinkles, and in case You do not mind to help me, please photograph a wrinkle (not the whole face, or not even a part of the face, and I do not need to know Your real name), then photograph it after one course of the treatment, or after one month of treatment. Then compare the photographs, (or post them for proffesional comparison) and please tell us if there is an actual healing of the wrinkle and the medication, that You used. If You do not want to post photos, You may send them to me at Danail_Angelov@Yahoo.com or to seivtcho@abv.bg
Metrodorus 25 Dec 2011
At the concentration shown to be optimal for mitochondrial protection, 100-500 nM, I think it would still look pretty blue.
Yep, it would be visibly blue ( giving a very pretty colour, mind you, when mixed in with the white aqueous cream BP) at a 100nm/mL concentration. I whipped some up just for fun, in the interests of ....interest? just to see if it would stain the skin. My skin is naturally lightly tanned, but I could detect no staining or colour change when the blue cream was applied.
As many face creams contain ingredients that aim to up regulate mitochondrial activity, this seems like a not unreasonable line to pursue. A quick google search shows no literature dealing with topical MB at nM/mL concentrations, for any intervention,and none dealing with wrinkle prevention/ skin tone/ with topical application of MB.