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Chronic rapamycin in AD

Jakare's Photo Jakare 20 Apr 2013

This paper claims that chronic rapamycin "halts the progression of Alzheimer's (AD)-like deficits" (in mice) by up regulation of heat shock proteins HSPs.


http://www.ncbi.nlm....pubmed/23585280



There is no access to the full paper through my university database. Anyone have access to it?

Also, I recently read somewhere that long term rapamycin does not produce long term immunosuppression to the extent it was previously thought to, but I can not find the paper. If that was to be true, may low dose rapamycin be one of the best researched antiaging drugs out there?
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ta5's Photo ta5 20 Apr 2013

Try clicking the link to the full study on Pubmed. It's the orange Open Access Oxford Journals button at the top-right.
http://pmid.us/full:23585280
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Jakare's Photo Jakare 20 Apr 2013

Try clicking the link to the full study on Pubmed. It's the orange Open Access Oxford Journals button at the top-right.
http://pmid.us/full:23585280


Sorry I linked the wrong paper. This is the one I meant:

http://onlinelibrary...0C259CB6.d03t01
http://onlinelibrary...1/jnc.12098/pdf

The newbie patrol is coming for me to take me where I won't hurt anyone! :ph34r:

Thanks! ;)
Edited by Jakare, 20 April 2013 - 07:56 PM.
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