Question about the duration of effect of n...
rhakshasa 11 Jul 2005
LifeMirage 11 Jul 2005
I've been wondering, do nootropics have "permanent effect" on the brain.
Some when taken for 6-12 months make changes that can last for several years.......permanent is a long time.
If I start taking piracetam, then stop, will the effect of the drug fade.
The effect is never as strong as being on them....I am not aware of any compound that would not fade to some extend.
I'm saying this because I want to start taking some nootropics (not sure yet which one, I will do more research) and I want to make sure I won't have to constantly buy pills (as I am young and do not have a lot of money, and anyway I don't have a credit card to buy them off the net).
Most accept money orders or checks. I would recommend reading Nootropic Q/A for more info.
Yours In Health
rhakshasa 11 Jul 2005
I've always been wondering is piracetem costy? (Or the more effective Aniracetam) Because like I said I don't have so much money but I'm still interested in paying a moderate price for it.
LifeMirage 11 Jul 2005
Yeah well longtime or permanent is almost the same thing.
Permanent is forever, nootropics effects do not last forever.
I've always been wondering is piracetem costy? (Or the more effective thing that start with A and end with cetem, don't really remember the name) Because like I said I don't have so much money.
Piracetam is pretty cheap, I would try that first.
rhakshasa 11 Jul 2005
AaronCW 14 Jul 2005
I am happy with the quality, prices, and service at Unique Nutrition and would be comfortable in endorsing the company. As LifeMirage indicated there are many sources available and the process of elimination involved in finding a good supplier can be painfull.
Cheers,
Rasputin
Guest_da_sense_* 14 Jul 2005
rhakshasa 15 Jul 2005
rhakshasa 15 Jul 2005
spider 15 Jul 2005
Start with piracetam first and I strongly recommend to buy capsules or tablets; no bulkpowder, yet.
Guest_da_sense_* 16 Jul 2005
I'm now a deprenyl "addicts", it changed my life more than all other supplements together. Stock up on deprenyl and start enjoying life
lemon 16 Jul 2005
Like the dope, eh? Dopamine that is.
For curiosity's sake, how much are you taking?
Guest_da_sense_* 17 Jul 2005
I'm currently taking 4-5 mg per day, one day liquid (2mg morning, 2mg afternoon) one day tablet (5mg morning), and i skip it on sunday.
So far I find this best supplement ever. It's not miracle of course. But since I uped my dose from 1mg daily, i have much more motivation for all type of things. Stuff i've been delaying for months i finnished in days. I even lowered my dose of other nootropics and don't take them regulary as before, and still feel better. It's not like I'm on drugs. I do get tired in the afternoon and if i can i get a nap. Also my sleep is much better than before and i seem to need somewhat less of it. Any kind of depression (i've had some mild problems before) is simply nonexistant.
Those who are very motivated might not feel much from deprenyl, but maybe they will feel piracetam, pyritinol and such. For me piracetam, pyritnol and such didn't show even close effects as deprenyl.
lemon 17 Jul 2005
[:o]
Guest_da_sense_* 17 Jul 2005
Please take a look at
http://www.imminst.o...f=169&t=7067&s=
If you have better information regardin deprenyl please post there. I've been thinking of slowly cuting my dose to 3 mg per day and then 2 mg per day, and if i stay the way i am now then good...if not i guess i'll up the dose again
What's "assuring" me is that deprenyl was originally used for depression, and was given to young people as well.
spider 17 Jul 2005
Today, I'm going to start with deprenyl for the very first time. I've decided to use about the same dosage as you do.
nuncle 18 Jul 2005
On the other hand, it's been suggested that the neuro-protective effects of deprenyl may work via non-dopaminergic channels. If that's the case, you'd probably need to take deprenyl every day to benefit. But note that the doses typically used in longevity studies in animal models are much higher than would be safe in humans without running the risk of the dreaded 'cheese effect' (because at high doses, deprenyl is no longer selective to MAO-B). The much-hyped rat studies that observed increases on the order of 20-50% in life span typically employed doses equivalent to about 30-100 mg / day in humans.
Bottom line: the dopaminergic effects of deprenyl probably don't require daily use, whereas the neuroprotective effects probably do, but may not have any substantial effects at 5 mg a day. That said, given that deprenyl _is_ used in much larger doses in animal models, often beginning at early ages, it's unlikely that 5 mg a day will have any adverse effect. But the jury's still out, and there's virtually no data on neuroprotective effects in healthy humans.
nuncle 18 Jul 2005
I've been wondering, do nootropics have "permanent effect" on the brain.
Well, it's certainly possible. There's no one-size-fits-all answer. Every substance is different, but it's certainly conceivable that some substance might interact with your existing neurochemistry in an irreversible manner. Obviously, the higher the dose you take of a given substance, the larger the chance of a permanent change occurring. At a sufficient dose, any number of beneficial substances become neurotoxic. Moderation may be the key (quite frankly, the doses people on this board claim to take for some substances I would find frightening, personally).
That said, provided you don't overdo it, it's unlikely you'll experience any permanent adverse effects. Just don't assume that a drug that gives you a nice buzz at 1 mg is going to give you 10 times as nice a buzz at 10 times the dose! The dose-response curve for most nootropics is, unfortunately, non-linear.
Guest_da_sense_* 18 Jul 2005
nuncle i really can't say which of deprenyls properties are working for me. I was taking 1-2mg daily for about a month, but i only noticed real effects when i uped my dose.
spider 18 Jul 2005
(da_sense)
Perhaps it takes about a month before you can notice any effects. What I'm trying to say is that perhaps if you hadn't uped your dosage, you would have experienced the same effects.
Nuncle, you seem to know quite a lot about biochemistry. Do you have a background in it?
Guest_da_sense_* 18 Jul 2005
spider 18 Jul 2005
Yes, this is a good idea. [thumb]
"I'll experiment for a couple of more weeks. " (da_sense)
Wow, you have a lot of patience. This is the only problem I have with nootropics and brain supplements: TIME. I don't mind spending the money or accepting a little health risk, but finding the right nootropics for yourself takes a huge amount of time. For example, if you are a high school student who has serious problems with one's learning capability and therefore want to start experimenting with nootropics, than he/she has to experiment 1 to 2 years before he/she will know what works for him. So, I think everyone must realize that nootropics or brain supplements will not give you a QUICK solution to your problem.
Fortunately, by reading this forum carefully, one is able to cut back some time.