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Can i trust pharmaceutical companies from...

plumper76's Photo plumper76 23 Jul 2015

Hi. I have been interested in the P7C3 compounds recently which have showed great promise in mouse models for treating brain injury and have been hypothesized to one day treat depression brain injury and neurodegenerative diseases. Having brain injuries myself a part of me wants to trial this compound or one of them there are at least four each one either more potent or in some cases seems to work in different parts of the brain. The articles I read said the compounds appear to be safe. I looked online and found Chinese pharmaceutical companies manufactoring them. But of course many issues like not seeing any human trials and trusting over seas companies. You can Google P7C3 and see a few articles telling remarkable things about how it restored mice cognition as well as a wiki page on the compounds. A big piece of me thinks that testing non human tests compounds made in China is a bad idea. What do you guys think should i just wait till human trials?
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Neutral's Photo Neutral 23 Jul 2015

I tried doing a little research on P7C3 and it could be promising, but it is way too early to assume that it will have the same effect on humans. Considering there haven't even been any human trials I wouldn't risk trying it just yet. Who knows the effect it could have on you? Also, you can't be sure that what you are buying from the Chinese pharmaceutical companies is even P7C3.

If you want to be the first human test subject go ahead and try it, although I wouldn't recommend trying it this early.
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plumper76's Photo plumper76 23 Jul 2015

Ok thanks I'll wait until it gets human trials and not overseas
Ok thanks I'll wait until it gets human trials and not overseas
Ok thanks I'll wait until it gets human trials and not overseas
Ok thanks I'll wait until it gets human trials and not overseas
Ok thanks I'll wait until it gets human trials and not overseas
Phone glitch
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plumper76's Photo plumper76 23 Jul 2015

Thoughts from others here?
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plumper76's Photo plumper76 24 Jul 2015

Bump
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littlePawn's Photo littlePawn 26 Jul 2015

Depends what you mean by pharmaceutical companies. If they're established companies with reputable reputations selling tabulated medications, then sure. But anything in powder form almost certainly is prone to heavy metals and other neurotoxic substances, unless subject to extensive spectroscopic testing.

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plumper76's Photo plumper76 26 Jul 2015

This would be in powder form and not yet tested on humans which greatly concerns me. My understanding is compounds that work in mice don't always work humans. Maybe someone can verify that. Also I did order a powdered compound from a Chinese pharmaceutical company and they never sent my the product. So all of there's things make me think perhaps I should wait till human efficacy is proven and if so I'd ideally buy from an American or European place.
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littlePawn's Photo littlePawn 27 Jul 2015

Yep definitely. Those are two major issues; untested in humans, and not being in a tabulated form with proper packaging from a reputable pharmacy. Also, I know a lot of people here speak highly of CoA (certificates of authentication). But they are worthless if they come from the manufacturer directly. All powdered medications need a third party lab to run spectroscopic testing.


Edited by littlePawn, 27 July 2015 - 01:39 AM.
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tarasco's Photo tarasco 14 Sep 2015

What about Sigma-Aldrich...?
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