Why were the following serotonergic medicines discontinued from the market if they invariably have positive mechanisms? - Mental Health

Why were the following serotonergic medici...

α-Methyltryptamine [αMT] (Indopan) – multiple serotonin receptor agonist, serotonin-norepinephrine-dopamine releasing agent (SNDRA), and weak RIMA
Oxaflozane (Conflictan) – 5-HT_1A, 5-HT_2A, and 5-HT_2C receptor agonist
Etryptamine [α-Ethyltryptamine (αET)] (Monase) – multiple serotonin receptor agonist, SNDRA, and weak RIMA

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