Triggering Excitatory and Inhibitory brain...
psychejunkie
27 Dec 2016
https://www.scienced...61226211235.htm
Scientists have discovered that networks of inhibitory brain cells or neurons develop through a mechanism opposite to the one followed by excitatory networks. Excitatory neurons sculpt and refine maps of the external world throughout development and experience, while inhibitory neurons form maps that become broader with maturation. This discovery adds a new piece to the puzzle of how the brain organizes and processes information. Knowing how the normal brain works is an important step toward understanding the nature of neurological conditions and opens the possibility of finding treatments in the future. The results appear in Nature Neuroscience.
Hello everyone,
according to new researches and results, both networks of excitatory and inhibitory circuits work together (in opposite manner) to form or change broader brain networks and connection between brain regions.
I have a theory which I want to put into a short-term test; that's related to indirectly put brain circuits to optimized plasticity situation.
forming or changing brain networks are the most effective mechanism one would choose to fight with a disorder or unwanted behavior.
What if by taking both excitatory and inhibitory drug, one would change brain networks more easily?
this should be done along with behavior modification or exercising (of course!).
like taking Modafinil + Pregabalin together plus Attention/Working Memory exercise or Mindfulness Meditation to boost/improve attention span.
I want to start testing this idea from this weekend for at least 3 weeks to examine what would be gained.
Mind_Paralysis
27 Dec 2016
Hmm... very interesting, I suppose this finally puts the finger on some things which have been theorized for some time.
Some very useful things for both ADHD and Schizophrenia could be gleaned from this!
Alas... I also think it's too early - this data won't be useful for some time.
However, if you really want to try this, practically, then perhaps a group buy for something like Brexpiprazol (SDAM - serotonin-dopamine activity modulator) or a Dopaminoid like OSU-6162 may be in its order.
As I understand it, the dopaminoids(? not entirely sure if this is what the inventor calls them...) are compounds which modulate monoaminergic levels in the brain, making them both inhibitory and excitatory at the same time - depending on dosage, they can be used to 'tune' the brain more accurately, having different effects in different regions of the brain, depending on the dopaminergic activity there.
Perhaps such a compound would be useful to give to adolescents with neurodevelopmental disorders, in order to allow their brains to more easily reach the correct functional end-point of their neuro-anatomy?
