LONGECITY

My acid reflux really annoying and seems not go away, it come and go...., is there any permanent cure for acid reflux? Thanks

Arguably, low fat and high fiber diet.

 

Rubenstein and Chen, 2014. Epidemiology of gastroesophageal reflux disease. Gastroenterology clinics of North America, 43(1), pp.1-14.

El-Serag et al, 2005. Dietary intake and the risk of gastro-oesophageal reflux disease: a cross sectional study in volunteers. Gut, 54(1), pp.11-17.

Becker et al, 1989. A comparison of high and low fat meals on postprandial esophageal acid exposure. American Journal of Gastroenterology, 84(7).

You could try d-limonene. It is supposed to have permanent effects after a while.

You could try d-limonene. It is supposed to have permanent effects after a while.

Limonene did it for me. Was on PPIs & H2 blockers before it. No sxs for many years now.

Beatine HCL and digestive enzymes. Also ceylon cinnamon, 5g/ day in 2 doses - works like a charm.

Do you have anything which is natural like vegetables/nuts/etc, not chemical/man-made?

 

I used to drink cow's milk everyday, it seems to work but I no longer drink milk for many many years.

Do you have anything which is natural like vegetables/nuts/etc, not chemical/man-made?

 

I used to drink cow's milk everyday, it seems to work but I no longer drink milk for many many years.

 

Cinnamon is natural. if you dont want beatine hcl, then you will have to get on fermented veggies, coriander, and fennel.

D-limonene is 100% natural and safe at normal doses.

I've had chronic GERD, or at least some kind of esophagus inflammation for about 30 years. Some people experience the reflux as acid coming all the way up to their mouths at times and I never noticed that, which made me wonder if I was actually suffering from GERD.

 

Docs prescribed PPIs, and then later Protonix (pantoprazole) for years and later tried OTC omeprazole. None of it had much or any benefit. I had pretty much given up. I figured all the -zoles would be minor variations of each other, but saw OTC nexium on the shelf one day and decided to try it. It was a dramatic improvement, almost a cure. The worst pain symptom that had afflicted me was a relatively persistent pain during the day while working, that would wax and wain but almost never totally go away, and was distracting. With nexium it is almost entirely gone. I can still have a raw sensation in the morning when I wake up. But once I'm up and about I don't have experience any symptoms.

 

I tried many various other remedies, including a couple bottles of D-limonene and never experienced any relief from any of them.

 

In the last few months I've started doing some extended fasting (and have been trending toward a lower-carb, higher fat diet over the last few years) and have since seen the remaining few symptoms diminishing still more. It's almost totally gone. Perhaps that is due to the reduction in C-reactive protein and hence inflammation that attends fasting. But I'm speculating there. Sometimes I forget to take nexium and haven't noticed a return of symptoms. I may try stopping it entirely and see what happens.

 

 

 

 

Edited by Postprandial, 21 March 2017 - 12:19 PM.

With Acid Reflux, is it advisable to eat raw garlic every day? 

Arguably, low fat and high fiber diet.

 

Rubenstein and Chen, 2014. Epidemiology of gastroesophageal reflux disease. Gastroenterology clinics of North America, 43(1), pp.1-14.

El-Serag et al, 2005. Dietary intake and the risk of gastro-oesophageal reflux disease: a cross sectional study in volunteers. Gut, 54(1), pp.11-17.

Becker et al, 1989. A comparison of high and low fat meals on postprandial esophageal acid exposure. American Journal of Gastroenterology, 84(7).

 

It could be other way around too. If someone also have IBS symptoms and GERD it worth a try to eliminate fiber. At least for some time.

Fast Tract Diet is based on this approuch and it have quite a good user records.

Anyway the goal is to reduce inflammation. Individuals have different causes of it, so it could be a few trials and errors involved.

And there is also anatomical deficiency of upper stomach sphincter - no option other than surgical or constant PPI treatment sadly.

Edited by Andey, 22 March 2017 - 10:27 AM.

IBS is pretty much bad bacteria buildup. Get oregano + clove  + peppermint + cinnamon (ceylon) essential oils, put 20 drops of each in 15 ml solution, and the solution should be them inserted in enteric coated caps (test one if it can take oil without breeaking first) use them for 2 weeks 1h before meals and you are golden.

Edited by dazed1, 22 March 2017 - 11:04 AM.

I've stemmed my everyday acid reflux to once every two weeks by this ritual:

 

For immediate relief:

 

1.3 g Potassium hydrogen carbonate, up to three times a day. Dissolve 1.3 g gently in little water and then fill up to around 200 ml (fill up the water glass), drink it immediately. Pull your head back while you drink to rinse the back of your throat (The branch to the nasal cavity).

 

For long-term relief?:

 

400 mg L-Theanine, up to three times a day and 500 mg KSM-66 Ashwagandha once in the evening. This is for chronic stress reduction which worked for me but there are many different approaches to achieve this. Maybe reduction of carbohydrate intake will help you too (as it did for me).

 

If all this doesn't help, then you might have something like out-of-control helicobacter pylori infection, an unfavourable gut flora or some autoimmune inflammation going on, but then again carbohydrate reduction and other phytochemicals might help you.

 

Peace

From experience...

 

it could be a hiatal hernia

Typically your doc won't check for it, so you should ask

 

I got mine diagnosed when they wanted to go and check for a helicobacter pylori infection, and found a hernia...

 

http://www.webmd.com...s/hiatal-hernia

 

I got some surgery

and no more acid reflux

 

Cheers

A

Edited by Anthony_Loera, 23 March 2017 - 07:28 PM.

From experience...

 

it could be a hiatal hernia

Typically your doc won't check for it, so you should ask

 

I got mine diagnosed when they wanted to go and check for a helicobacter pylori infection, and found a hernia...

 

http://www.webmd.com...s/hiatal-hernia

 

I got some surgery

and no more acid reflux

 

Cheers

A

 

They found that you had a hiatal hernia from the h pylori breath test? Or did you have to do an endoscopy/barium swallow to detect the hernia?

https://www.ncbi.nlm...pubmed/22207112

 

From experience...

 

it could be a hiatal hernia

Typically your doc won't check for it, so you should ask

 

I got mine diagnosed when they wanted to go and check for a helicobacter pylori infection, and found a hernia...

 

http://www.webmd.com...s/hiatal-hernia

 

I got some surgery

and no more acid reflux

 

Cheers

A

 

They found that you had a hiatal hernia from the h pylori breath test? Or did you have to do an endoscopy/barium swallow to detect the hernia?

 

 

Endoscopy..

the breath test won't do it.

 

Cheers

A
 

For those with GERD, please try and avoid getting pulmonary bronchiectasis and opportunistic infections such as non-tuberculosis mycobacteria (NTM) which are very difficult to treat and require the same antibiotic course as tuberculosis (12-18 months of a 3-4 strong AB cocktail!). Re-infections are frequent. NTB are environmental and grow mostly in waters and soil; pay attention to hot tubs, jacuzzi, spa's, showers etc even if well maintained. NTM infections are on the grow! Research on GERD and NTM.

 

"...In recent years, the relationship between NTM and non-CF bronchiectasis has been further elucidated.52 Some authors have posited that gastroesophageal reflux may cause bronchiectasis and predispose to subsequent NTM pulmonary disease due to chronic aspiration, but published associations have not been consistent. 52,53 There is a reciprocal relationship between bronchiectasis and NTM pulmonary disease. NTM can cause bronchiectasis by destroying the bronchial anatomy, and bronchiectasis can predispose to NTM colonization/disease due to impaired host local defenses.54,55 ..."

 

Stout JE, Koh WJ, Yew WW. Update on pulmonary disease due to non-tuberculous mycobacteria. Int J Infect Dis. 2016;45:123-34.

https://www.ncbi.nlm...pubmed/26976549

I wonder if agmatine could help GERD or Laryngopharyngeal Reflux through NOS inhibition. I’m still learning about what it inhibits and what it boosts though. Anyone know with more detail than stimulating NOS in blood vessels but inhibiting NOS in immune and nervous system? There could be several other factors at play, but I didn’t start having GERD or LPR symptoms until I stopped using agmatine and too much p5p/methylfolate/Methyl-b12.
I’ve been hesitant to use it again since the feeling like my throat is closing is pretty scary and don’t want to make it worse if I’m wrong.

Role of nitric oxide in lower esophageal sphincter relaxation to swallowing.
Yamato S, et al. Life Sci. 1992.
Show full citation
Abstract
Studies were performed in the opossum to define the role of the L-arginine-nitric oxide (NO) pathway in lower esophageal sphincter (LES) relaxation to swallowing and vagal stimulation in viv and intramural nerve stimulation in vitro. In vivo, L-NAME, a water soluble NO synthase (NOS) inhibitor, caused antagonism of LES relaxation due to reflex-induced swallowing. L-NAME (20 mg/kg i.v.) reduced the amplitude of swallow induced relaxation from 88% to 28%. LES relaxation due to electrical stimulation of peripheral end of decentralized vagus nerve was also antagonized. The effects of L-NAME were reversed by L-arginine, but not by D-arginine. L-NAME treatment did not antagonize LES relaxation to intravenous administration of isoproterenol. In vitro, NO and sodium nitroprusside (SNP) caused a decrease in the sphincter tone. The relaxing effect caused by NO and SNP was not antagonized by tetrodotoxin or omega-conotoxin. Inhibitors of NO synthase, L-NMMA and L-NNA, caused slight increase in the spontaneous resting LES tone and concentration-dependent antagonism of electrical field stimulation (EFS) induced LES relaxation. L-NNA (10(-4)M) abolished EFS induced LES relaxation at low frequencies (less than 5 Hz) and antagonized the relaxation to a value 20% of the control at 20 Hz. The antagonistic action of L-NMMA and L-NNA was unaffected by D-arginine but was reversed by L-arginine. The inhibitory effect of NO, SNP, or two other putative inhibitory neurotransmitters (VIP and CGRP) on the LES was not antagonized by L-NNA. These studies show that inhibitors of NO synthase selectively antagonize LES relaxation to all three modes of intramural inhibitory nerve stimulation including physiological swallowing. These studies suggest that the L-arginine-nitric oxide pathway is involved in physiological relaxation of the LES.
Edited by GreenmachineX, 21 February 2018 - 12:47 PM.

You could try d-limonene. It is supposed to have permanent effects after a while.

 

 

Worked for me.

You could try d-limonene. It is supposed to have permanent effects after a while.

Worked for me.

How does d-Limonene work for GERD?

You could try d-limonene. It is supposed to have permanent effects after a while.

Worked for me.

Worked for me also.

You could try d-limonene. It is supposed to have permanent effects after a while.

Worked for me.

How does d-Limonene work for GERD?

https://fixyourgut.c...erd-d-limonene/

http://www.lifeexten...artburn/Page-01

Or JFGIB!
Edited by tintinet, 22 February 2018 - 08:24 AM.

Manuka Honey cured mine about 11 years ago. I had gastritis for a while, and the GERD eventually caused problems with swallowing food... may have been caused by h pylori, but not sure.

 

The honey allowed me to swallow food properly within a few days and within 2 weeks the stomach symptoms went away

You could try d-limonene. It is supposed to have permanent effects after a while.

Really?

Be very careful.  I was taking zantac three or four times per week for relief which was not 100% effective.  Then I learned that zantac may be carcinogenic.  Thenn I found Limonene and it was far superior to zantac.  Did not have a single episode of acid reflux.  Then, after several months, I ended up in the hospital with serious inflammation in my esophagus.  I do not think the limonene had any part in that.  My point is, if you are having symptoms, get scoped to see if there is a condition that should be addressed.  I had zero symptoms after beginning limonene until I had a major episode.  Sometimes it is better to have symptoms so that you can address them.  If you are symptom free, you will not know you have a problem until the dam breaks so to speak.

From experience...

it could be a hiatal hernia
Typically your doc won't check for it, so you should ask

I got mine diagnosed when they wanted to go and check for a helicobacter pylori infection, and found a hernia...

http://www.webmd.com...s/hiatal-hernia

I got some surgery
and no more acid reflux

Cheers
A

What surgery did you have?

Be very careful. I was taking zantac three or four times per week for relief which was not 100% effective. Then I learned that zantac may be carcinogenic. Thenn I found Limonene and it was far superior to zantac. Did not have a single episode of acid reflux. Then, after several months, I ended up in the hospital with serious inflammation in my esophagus. I do not think the limonene had any part in that. My point is, if you are having symptoms, get scoped to see if there is a condition that should be addressed. I had zero symptoms after beginning limonene until I had a major episode. Sometimes it is better to have symptoms so that you can address them. If you are symptom free, you will not know you have a problem until the dam breaks so to speak.

What was it?

It was preliminarily diagnosed as ul eruptive esophigailis (forgive spelling).  Due to the degree of inflammation, there could not get a good picture so I an scheduled for a send scope next months.  Put me on 40mg 2x per day.  I expect to be diagnosed with Barrett's esophagus as both my brother and son have been so diagnosed.

I was having a private dialogue about this but I think it might benefit others to share it publicly.  I've had both GERD and LPR for my entire life, which has been severe at times, and caused ear infections, sinus problems, asthma, sharp pains in my lungs, swelling in the esophagus that impacted my ability to swallow, and more.  I am able to prevent GERD and LPR symptoms completely by eating predominantly meat and avoiding acidic food and beverages.

 

 

The carnivore diet helps by avoiding fermentable material that feed gut flora and produce gas. Gas puts pressure on the lower esophageal sphincter and causes it to open more readily.

Dietary acids activate pepsin that was previously refluxed and allow it to cause harm. Higher pH deactivates pepsin.

 

 

The carnivore diet is animal-based and excludes plants.  Some people eat eggs and dairy, others eat just meat.  I personally eat just meat.  It has helped my health and well-being in many ways beyond just GERD.

Have I figured out the cause?  No.  I have an idea that the microbiome is responsible in my case, but I don't know for sure.  What I do know is how to prevent the symptoms and live well, so I don't care too much if I never figure out the root cause.

 

D-limonene didn't help me and seemed to irritate my gut with longer use.

 

If you want to learn more about the contribution of fermentable plant material to this problem, read this book: https://www.amazon.c...k/dp/B007WZHCWK

 

If you want to learn about the contribution of dietary acids to the problem, read this book: https://www.amazon.c.../dp/B00ILHW4L2/

 

There is an alternative approach to this that involves a very low-fat vegan style diet.  This will minimize pepsin production with its low protein content and accelerate gastric emptying due to both low protein and fat content.  Depending on your microbiome, there may be massive gas produced and you may still get alot of reflux, so it doesn't work for everyone.  This type of diet causes a significant loss of muscle mass and often disturbs mental health so I wouldn't recommend it.

 

I haven't read this whole thread so maybe this was stated. Apple cider vinegar and zegrid are life savers for me. At times mine is so bad that I wake up in the middle of the night choking and gasping for air. Its very frightening. But the 2 above are my life savers and prevent those episodes!