"Most Potent Longevity-Extending Pharm...
mccm98
21 Mar 2017
Science Alert Write Up:
http://www.scienceal...low-down-ageing
Journal Article:
http://www.impactjou...65&path[]=22203
"“In total, we found six new groups of molecules that decelerate the chronological ageing of yeast,” said biologist Vladimir Titorenko from Concordia University.
As the authors report in Oncotarget, one of these compounds – a specific extract of willow bark (Salix alba) – is the most potent longevity-extending pharmacological intervention ever described in scientific literature. In testing, the willow bark extract increased the average chronological lifespan of yeast by 475 percent and the maximum chronological lifespan by 369 percent.
If these findings can be replicated in something other than yeast, it’s a major discovery, outperforming the anti-ageing effects of both rapamycin and metformin. And in addition to slowing ageing, the compounds may also have beneficial effects on cellular processes when it comes to preventing related diseases, such as cancer, the researchers say. The other extracts come from Cimicifuga racemosa, Valeriana officinalis L., Passiflora incarnata L., Ginkgo biloba,and Apium graveolens L.."
This would seem to support the idea that aspirin is a potent anti aging drug considering it is derived from Willow Bark.
Thoughts?
http://www.scienceal...low-down-ageing
Journal Article:
http://www.impactjou...65&path[]=22203
"“In total, we found six new groups of molecules that decelerate the chronological ageing of yeast,” said biologist Vladimir Titorenko from Concordia University.
As the authors report in Oncotarget, one of these compounds – a specific extract of willow bark (Salix alba) – is the most potent longevity-extending pharmacological intervention ever described in scientific literature. In testing, the willow bark extract increased the average chronological lifespan of yeast by 475 percent and the maximum chronological lifespan by 369 percent.
If these findings can be replicated in something other than yeast, it’s a major discovery, outperforming the anti-ageing effects of both rapamycin and metformin. And in addition to slowing ageing, the compounds may also have beneficial effects on cellular processes when it comes to preventing related diseases, such as cancer, the researchers say. The other extracts come from Cimicifuga racemosa, Valeriana officinalis L., Passiflora incarnata L., Ginkgo biloba,and Apium graveolens L.."
This would seem to support the idea that aspirin is a potent anti aging drug considering it is derived from Willow Bark.
Thoughts?
Exception
22 Mar 2017
I agree that aspirin is a geroprotector. I've seen a few studies showing that it increases lifespan in worms and flies and it is known to reduce platelet aggregation.
This is certainly intriguing, but if this is the first study on these extracts, I wouldn't get too excited until they're replicated in an animal model.
Turnbuckle
22 Mar 2017
This paper has already been discussed on a couple of threads, in particular this one.
nickdino
24 Mar 2017
In testing, the willow bark extract increased the average chronological lifespan of yeast by 475 percent and the maximum chronological lifespan by 369 percent.
How does that work? Shouldnt those numbers be swapped?
How does that work? Shouldnt those numbers be swapped?
