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What should I try first for depression,SAD...

Patrisha's Photo Patrisha 16 Sep 2017

Hi,can anybody help me and tell me with witch supplements,nootropics etc should I start:I have SAD,SCT,depression..the best word to describe me is melancholy..I have also raising thoughts how something bad will happend..I'm also extremely sensitive person..So if you can suggest something to start with that would be grate..I tried only Modafinil and it makes me sweating aloth,makes me sleepy,but if I manage to get up I'm a bit energized which is not usuall for me but this nervous energized and it makes my memory worst also..I tried it only 2 times though.Sorry for my English,it's my second language.
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Jiminy Glick's Photo Jiminy Glick 16 Sep 2017

I don't know what SAD and SCT are but I would go with tryptophan and phenylalanine powder for depression and then throw some other stuff in there to jazz it up, maybe an ashwagandha. 


Edited by Jiminy Glick, 16 September 2017 - 05:13 PM.
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samson75's Photo samson75 16 Sep 2017

If your depression is not severe (you don't have times when you suffer so much

that you want to kill yourself) you could try natural antidepressants like St John's wort,

5-HTP or L-tyrosine for exemple.

Chemical anti-depressants don't work for all and have serious side effects (for me constant

anxiety and fatigue).

That condition is awful, i think it would be reasonable to seek professionnal help...if you don't

want to follow the chemical path may be you could see a naturopath.


Edited by samson75, 16 September 2017 - 06:30 PM.
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Patrisha's Photo Patrisha 16 Sep 2017

Thank you for answers.Jiminy-SCT is sluggish cognitive tempo and SAD is social anxiety.
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Finn's Photo Finn 16 Sep 2017

Usually when it comes to mental health related discussion on Internet, many if not most people associate abbreviation SAD with Seasonal Affective Disorder. SA might be clearer.


Edited by Finn, 16 September 2017 - 08:21 PM.
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Jiminy Glick's Photo Jiminy Glick 18 Sep 2017

Finn Patrisha just said something different than you. You said it is seasonal and she said it is social anxiety. Is it seasonal social anxiety? 

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gamesguru's Photo gamesguru 19 Sep 2017

depending on the source of your depression, it could be inflammatory, different things will help.  obviously lifestyle changes are always a good choice, but that hardly needs saying.  turmeric is another good choice, not only for the inflammation but because it also has noteworthy glutamate antagonizing effects which might relieve symptoms in ways which you would find surprising, or refreshing

 

as for the SCT and anxiety, their causes can be largely explained by too much neurotransmitter.  for SCT it's too much dopamine (the opposite of ADHD), and for anxiety it's too much serotonin (but try not to contrast it with depression, because the regions affected differ greatly).  basically  in your case i would recommend indian snake root (it lowers NT levels), as well as a host of other generic goodies, magnesium, zinc, yada yada.  a blanaced lifestyle will have the effect of correcting what Jiminy mentioned: amino acid levels, which are crucial for NT levels.  making sensible food choices will also help to ensure an appropriate intake of minerals and vitamins only recently known have pivotal roles in cognition and mood

 

in your case i would also consider trialing rhodiola and shilajit

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Patrisha's Photo Patrisha 20 Sep 2017

Thank you gamesguru.:)
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RegainBrain's Photo RegainBrain 20 Jun 2018

as for the SCT and anxiety, their causes can be largely explained by too much neurotransmitter.  for SCT it's too much dopamine (the opposite of ADHD)

 

Can you add sources or at least explain your statement?

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gamesguru's Photo gamesguru 20 Jun 2018

anxiety sufferers have too much glutamate and serotonin, they tend to be disagreeable and analytical while their responses to stress and their homeostatic mechanisms are all out of whack.

 

This is why amphetamines are prescribed to ADHD patients and SSRIs to anxious individuals.  They boost these neurotransmitters, counter-intuitiely, but the net long-term effect is in the opposite direction of what you're thinking.  Taking blood pressure medicine may relieve your heart, but on the other hand leaving a slight wound exposed to the environment may stimulate the immune system when most would assume a bandage is prudent.

 

Half of these medicines have a greater effect on the receptors on the part of your brain that does the sending, not the receiving.  The main purpose of these guys is a volume switch, the receivers communicate back with secondary messengers, basically  hey I'm not getting much of a signal, or hey shut the f*ck up for a minute dawg.  The "auto-receptors" on the presynapse then either upregulate or downregulate, more of them means more self-inhibition on the receiver's side.  But less auto-receptors mean more neurotransmitter can get out before the quiet signals register.  Either way, medicines alter the situation not always in a way you can predict.

 

A lot of things used around here for anxiety have a mixed effect on both sides.  Magnesium, lemon balm, ginseng and others probably target the presynapse a bit more while Valerian, GABA, and taurine are mostly post-synaptic.  You want the former


Edited by gamesguru, 20 June 2018 - 10:32 PM.
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