Activating NQO1 without Downregulating PARP?
recon
08 Nov 2017
Hi,
Any supplements to activate NQO1 without downregulating PARP?
I get that inhibiting PARP is effective in raising NAD+ levels and that PARP is over expressed in the aged.
However, I believe that PARP is a response to large oxidation damage/ DNA damages, and is important not to decrease, especially for younger person like me.
Anyone knows of ways to activate NQO1 that doesn’t involve inhibiting PARP?
Any supplements to activate NQO1 without downregulating PARP?
I get that inhibiting PARP is effective in raising NAD+ levels and that PARP is over expressed in the aged.
However, I believe that PARP is a response to large oxidation damage/ DNA damages, and is important not to decrease, especially for younger person like me.
Anyone knows of ways to activate NQO1 that doesn’t involve inhibiting PARP?
