34 replies to this topic

[david ellis]

 

 

 I am taking 50 mg of MK4 about 5-6 times a week.       My cardiologist was impressed that my cardiac calcium load was at a slow rate.  Plus the total cardiac is low too.   Visit before that, last year, he was anticipating me for stents.   I had a 70% blockage revealed by a cat scan movie.   The blockage is gone now.

 

 

 

Have you stacked it with any other supplement (Vit. C, D, etc.) or taken alone? I'm taking the Super K by LE and thought to switch to the Koncentrated K but changing to such a great amount always worried me a bit if there could be some side effect on the long term. For how long did you take the Koncentrated K to achieve that result? Did you stop it?

Thanks

 

I take Vit D(5000 mcg), and a full complement of B vitamins.     Vitamin K plays a role in the control of calcium in the blood.   The original Japanese study used 45 mg to successfully strengthen bones.   The website selling KoncentratedK  has supporting research about the safety and effectiveness of vitamin K treating heart, bone, kidney, and cancer.    Because of budget problems I am taking a 25 mg dose now.   I see my cardiolgist in December.  I will know then something about how much more calcium has been deposited in the coronary arteries.

[jjnz]

To mimic the Japanese osteoporosis studies that used 45-90mg daily.

Mind if I ask, how did that go ?
Has there been an improvement?
Curious because I'm just been diagnosed with osteoporosis (at 45)
Strategy is calcium vit d , k2 (mk4) prunes nr and vibration therapy

[Woody42]

Mustardseed41 said the MK4 helped remineralize his cavities would this just be rebuilding dentine or is there any rebuilding of the enamel ?

[RSRCH]

 

This is interesting.

[BigBalli]

Dropping this here for anyone coming to this thread fresh since there's a lot of MK-4 vs MK-7 mixing in the older posts. MK-4 and MK-7 aren't interchangeable and you get into trouble when you pick a dose from an MK-7 study and buy MK-4, or vice versa. MK-4: short half-life (hours), used in the Japanese osteoporosis trials at 45 mg/day split into 2-3 doses. The only form with strong human outcome data at pharmacological doses. MK-7: long half-life (about 3 days), studies use 180-360 mcg/day for cardiovascular endpoints. Once-daily is fine. Less outcome data but better tolerated and much cheaper. If the goal is slowing coronary calcium, MK-7 at 180-360 mcg has the cleanest evidence at reasonable cost. If the goal is osteoporosis reversal mimicking the Japanese trials, you need 45 mg MK-4 split through the day. Stacking both is fine and what most combo products do. One practical note: K2 works with K1 and D3 as a system. Low D3 status can blunt K2's effect on arterial calcium. If you're supplementing K2 long-term, check 25(OH)D and aim for 40-60 ng/mL before drawing conclusions about whether it's working.