Vitamin K has an anabolic effect on glycos...
Lufega
31 Jul 2011
What impressed me about this study is how the used the word "Anabolic" to describe the level of GAG synthesis produced. It doesn't state which type of vitamin K was used or dose. Instead of supplementing with Glucosamine, chondroitin and HA, perhaps all we need is more vitamin K ? Anyways, this lends more support against the low fat mantra and for eating butter which is rich in vitamin K (mk-4). It can also explain why some people report skin benefits from supplementing vitamin K
[The role of vitamin K in the metabolism of connective tissue biopolymers (review)].
[Article in Russian]Sharaev PN.
Abstract
Metabolism of connective tissue biopolymers was studied under conditions of various content of vitamin K in the body. The data obtained suggest the existence of a new metabolic effect of vitamin K--its participation as an allosteric activator in regulation of glucosamine synthetase (EC 5.3.1.19). The anabolic effect of vitamin K on connective tissue is apparently related to an increase in the rate of biosynthesis of glucosamine-6-phosphate--general precursor of glycosaminoglycans, glycoproteins and hexosamine-containing glycolipids.
PMID:6369774
