LONGECITY

Sounds like a marketing ploy from the corn industry.

There are drawbacks consuming diets high Omega 6 rich polyunsaturated oils, like corn oil.

They are associated with shortened DNA telomeres, driving insulin spikes and transgenerational obesity.

This makes an interesting counterread:

http://high-fat-nutr...d-fed-mice.html

Another thing:

There is what's known as the 'israeli paradox',  associating high linoelic acid diet with poor health outcomes:

for more info:

Berry, E. M. (2001). Are diets high in omega-6 polyunsaturated fatty acids unhealthy?. European Heart Journal Supplements, 3(suppl D), D37-D41.

http://eurheartjsupp..._D/D37.full.pdf

I have heard some pretty good things about people who eat a lot of corn. Kenyan runners for instance. Popcorn is supposedly very high in antioxidants/gram. I'm going to stick to nuts and olive oil for the time being. But when I want snacks I typically use cornoil and popcorn.

Another thing:

 

There is what's known as the 'israeli paradox', 

Mmmm, well... Israeli males have one of the lowest rates of CVD worldwide and one of the highest life expectancies... Still can't see a paradox there!

In mice...nuff said.

There were other things going on in the corn oil experimental group.

Move along people.  We already know that lowering fructose and increading intake of monos is a good thing.  (better than omegas or saturated fats)

 

 

Mmmm, well... Israeli males have one of the lowest rates of CVD worldwide and one of the highest life expectancies... Still can't see a paradox there!

 

Isr J Med Sci. 1996 Nov;32(11):1134-43.

Diet and disease--the Israeli paradox: possible dangers of a high omega-6 polyunsaturated fatty acid diet.

Yam D, Eliraz A, Berry EM.

Abstract

Israel has one of the highest dietary polyunsaturated/saturated fat ratios in the world; the consumption of omega-6 polyunsaturated fatty acids (PUFA) is about 8% higher than in the USA, and 10-12% higher than in most European countries. In fact, Israeli Jews may be regarded as a population-based dietary experiment of the effect of a high omega-6 PUFA diet, a diet that until recently was widely recommended. Despite such national habits, there is paradoxically a high prevalence of cardiovascular diseases, hypertension, non-insulin-dependent diabetes mellitus and obesity-all diseases that are associated with hyperinsulinemia (HI) and insulin resistance (IR), and grouped together as the insulin resistance syndrome or syndrome X. There is also an increased cancer incidence and mortality rate, especially in women, compared with western countries. Studies suggest that high omega-6 linoleic acid consumption might aggravate HI and IR, in addition to being a substrate for lipid peroxidation and free radical formation. Thus, rather than being beneficial, high omega-6 PUFA diets may have some long-term side effects, within the cluster of hyperinsulinemia, atherosclerosis and tumorigenesis.

I have heard some pretty good things about people who eat a lot of corn. Kenyan runners for instance. Popcorn is supposedly very high in antioxidants/gram. I'm going to stick to nuts and olive oil for the time being. But when I want snacks I typically use cornoil and popcorn.

It's one thing to eat corn, but to remove and extract the oil is a no no. The oil in corn is bioactive and your body makes inflammatory hormones and free-radicals from them. Animals that contain a lot of polyunsaturated-fats in their cells, age faster than animals that are mainly saturated or monounsaturated.

The Tarahumara Indians of Mexico, eat mainly a diet consisting of corn, beans and squash, and they are known to be completely free of atherosclerosis well into old age.  

Corn is low-fat/high-fiber. Mostly carbohydrates.

Corn-oil is pure fat.

Big difference.

Move along people.  We already know that lowering fructose and increading intake of monos is a good thing.  (better than omegas or saturated fats)

Why? If you consume too much fructose, your body will make monounsaturated-fat from the excess fructose. Perhaps its not the fats we can make ourselves that are the problem... perhaps it's the fats we can't make that have the potential to be problematic.

Is this corn oil result consistent with other reports in the C57Bl/6 mouse?  "High Fat" diets are generally a good way to shorten the life of a mouse, but I suppose those are high in SAFAs.   A one-off mouse experiment that is inconsistent with a lot of other work is not terribly convincing.  Why should a corn oil megadose make a mouse live longer, much less a human?  How much sugar or other fast carbs are in the "normal" diet?  The fact that trigs went down with the corn oil is not surprising- it's a "low carb" diet, after all...  But still, this is a strange result.  Who ran this experiment, anyway?  Do they have a history in the field?  Was this done properly?

 Why should a corn oil megadose make a mouse live longer, much less a human? 

I was thinking along the lines of autophagy. 

ω-6 Polyunsaturated fatty acids extend life span through the activation of autophagy

 

 Why should a corn oil megadose make a mouse live longer, much less a human? 

 

I was thinking along the lines of autophagy. 

 

ω-6 Polyunsaturated fatty acids extend life span through the activation of autophagy

Interesting paper.  It works in c. elegans and mammalian cells, at least.  It would be cool if someone looked at that in mice.  At this point, the mouse corn oil result goes against so much other work that I still have to wonder if there's not something else going on, like poor husbandry killing the controls, and the radically different diet doing something to work against the husbandry issues. 

Autophagy being as important as it is, I hope that it happens that we've found a new way to induce it.  All the negative n-6 PUFA epidemiology is a concern, but then there's all that positive n-6 data, mostly in CVD...

I came across the full text of the corn oil study.  They took care to keep the corn oil fresh, cold and unexposed to light, which might make a difference. Corn oil is high in tocopherols, ubiquinone, and plant sterols, which they say is likely responsible for lowering inflammation and extending life.