LONGECITY

I saw this article from 2016 today on lead and crime and its persistence today in the environment.

Glycation is an interest in aging but its other effects are disastrous even at such low levels. Read the whole thing if you can.

http://www.motherjon...children-health

After all, leaded gasoline has been banned since 1996, so even if it had a major impact on violent crime during the 20th century, there's nothing more to be done on that front. Right?

Wrong. As it turns out, tetraethyl lead is like a zombie that refuses to die. Our cars may be lead-free today, but they spent more than 50 years spewing lead from their tailpipes, and all that lead had to go somewhere. And it did: It settled permanently into the soil that we walk on, grow our food in, and let our kids play around.

That's especially true in the inner cores of big cities, which had the highest density of automobile traffic. Mielke has been studying lead in soil for years, focusing most of his attention on his hometown of New Orleans, and he's measured 10 separate census tracts there with lead levels over 1,000 parts per million.

To get a sense of what this means, you have to look at how soil levels of lead typically correlate with blood levels, which are what really matter. Mielke has studied this in New Orleans, and it turns out that the numbers go up very fast even at low levels. Children who live in neighborhoods with a soil level of 100 ppm have average blood lead concentrations of 3.8 μg/dL—a level that's only barely tolerable. At 500 ppm, blood levels go up to 5.9 μg/dL, and at 1,000 ppm they go up to 7.5 μg/dL. These levels are high enough to do serious damage.

What does Glycation have to do with Lead?

Heavy metals are what's apparently needed to make AGEs.

Sigh, ok, since I apparently need to reference something that's already been repeatedly referenced on this board if you do a simple search you can come up with the following:

https://www.ncbi.nlm.../pubmed/9680171

https://www.ncbi.nlm...les/PMC3583887/

http://www.sciencedi...735109716015989

http://pubs.acs.org/...rnalCode=crtoec

http://www.justabout...-in-skin-aging/

https://www.ncbi.nlm...les/PMC3282805/

Heavy metals are not needed to make AGEs. Metals can react with things to increase oxidation which will promote glycation. They don't need to be heavy metals or lead. Other metals like iron and copper can do this too. They can make things worse, like anything that increases oxidation.

Iron is a heavy metal, so is copper. Zinc does it too. I understand though, just a catalyst then, but still, lead is a huge problem and it's in the soil and everywhere.