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How do we know?

Believer's Photo Believer 24 Jan 2018

That the body can't already remove these exotic waste materials that build up, like AGEs?

The Wikipedia page says that the human body can remove AGEs although supposedly not perfectly or fully.

https://en.wikipedia...oduct#Clearance

 

1. We know that the body can remove calcium buildup in the arteries via producing a protein which binds to the calcium. For this you need vitamin K, A, D and potentially others.

2. We know that the body can remove lipofuscin via at least l-carnitine, which the body synthesizes itself although perhaps not in large enough quantities.

3. We know that the body is able to remove atherosclerotic lipoprotein buildup.

4. We know that the body is able to remove amyloid beta via ApoE. 

 

Some scientists still to this day claim that calcification of arteries cannot be resolved naturally and special enzymes must be made or found (in bacteria) to remove the calcium. This is total ignorance on their part. The same holds true for lipofuscin and  atherosclerotic plaque.

Some scientists were so certain that the body cannot remove amyloid beta and it's a waste product that has to be removed via a billion-dollar synthetic enzyme sold to people (KA-CHING!). Turns out that first of all the body can remove it and secondly it may not be a waste product after all.

 

It seems to me that there is more evidence that fixing the accumulating mutations in cells and restoring the telomere length (for cell division AND gene expression) is sufficient to resolve aging, than there is evidence that we age due to an incapability of removing "waste products" that build up in our body and prevent our body's functioning.

 

 

 

 

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QuestforLife's Photo QuestforLife 30 Jun 2018

The only way to know for sure is to restore youthful gene expression to our cells, give them sufficient time to clear out the 'backlog' of waste and then see what, if anything, continues to build up. For what it's worth, I agree with you that most if not all can be cleared. But there may be other waste products that build up over extremely long timescales (100s years), and for those we'll need new enzymes or nanobots.
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