LongeCity - Business of Longevity

10 questions on the business of longevity! Good luck!

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Which of the following 2 are current outspoken investors about extending maximum human lifespan and treating aging itself as a disease?
Mark Zuckerberg and Warren Buffett
Hans Rausing and Sam Walton
Li Ka-Shing and Wang Jianlin
Jim Mellon and Michael Greve
Susanne Klatten and Amancio Ortega

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Which of the following companies are developing therapeutic solutions to human aging?
Jangsu biotechnologies, described as a North korean special economic zone venture for highest respect of the great leader, democracy, peace and good health for all old people. The company is largely funded by chinese investor Yongyuan Nianqing.
Nanosmart therapeutics, provides visualization of agerelated pathologies on a nanoscale level screening cells and developing atomic scissors to remove agerelated changes, founded in 2016 by 18-yearold Harvard PhD student Congming Daxuesheng.
Ichtyosarus Therapeutics, a SENS-funded company
Monsanto, through a spin-off project focused on pluripotent stem cells from patented seeds.
AgeX located in Alameda, California, founded in 2017 by Michael West

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Which of the following alternatives is the most accurate reason holding back investments in aging research biotech?
Lack of tax revenue, governments are not receiving enough tax to properly fund aging research, if wealthy people paid more in tax that money would go directly to aging research.
Too little AI in healthcare, lack of innovative disruption and thoughtleaders, non-inclusive work environments, failure to implement blockchain contracts and cryptocurrencies.
Regulatory frameworks slowing tech transfer, a high-risk long-term investment field which venture capital funds often have difficulty at evaluating and perceiving as a realistic goal.
There is a lot of progress, but the people in charge wants aging research breakthroughs to happen in secret so that future treatments will be reserved for an elite that will be saved while the rest of humanity will be denied rejuvenation.
The general public thinks that age-related disease is a good thing and therefore actively seek to prevent medical breakthroughs to keep the status quo.

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Which of the following list of companies are also actively working on longevity?
Unity, Insilico medicine, Covalent biosciences, Calico, Oisin, Elevian
Pakistan Stemcells, Wrinkleless, Timefreeze, Oxford Elite Clinic
RNA-cycle therapeutics, Pharmacoboost, Glycocalyx genetics
Youngpill, Protoelisa, Mitoxidant solutions, RapaYourDog
Dharma wellness, Scifi-lab, Senoblast Atlas Project, CryptoHealthSpa

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Which year has had the biggest amount of investment on aging research so far?
2014
2008
2018
2015
2011

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A certain sector within regenerative medicine has received a lot of hype and also been involved in many cases of medical malpractice, which one?
Treatments of male pattern baldness, often frauds customers with things that do not work.
The cosmetics industry, the creams are inefficient and overpriced.
Stem cell clinics, unapproved and often placed in countries with poor regulation marketed to desperate people resulting in disease and death, only FDA approved for hematopoietic stem cells.
Leg lengthening clinics, doctors have been accused of causing mutilation and trying to advice short but healthy people to have the procedure in order to achieve success in life. For example a scandal erupted after a 1.80 m tall height dysphoric man had his height increased to 2.20 m and developed circulatory problems in the legs.
Cosmetic dentistry, such as the Manhattan clinic that was sued by Donald Trump for not being able to produce a material to make his tooth veneers white enough.

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What was characteristic of 2018 when it comes to investment in the longevity biotech business?
Belief in the market, many smaller companies are created, high volatility and a focus on DIY biology.
A sharp increase in investment, a focus on senolytic therapies, gene therapy resurfaces as an important trend, profitability of companies remains unclear
Many companies going offshore because of tighter regulations, fear about the US economy, CRISPR is used to insert "longevity genes" in humans by israelic scientists.
Big data becomes a tool for analytics, nextgeneration sequencing is seen as an important discovery.
Interleukin-2 is seen as holding the key to fighting cancer through immunotherapy and lowering levels of it turns out to extend lifespan, it becomes the biggest focus among investors, market remains stable.

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Why do many scientists primarily want fundamental aging processes classified as a disease?
In order to target aging damages before they surface as what is currently defined as clinical disease, this could also increase funding for that specific purpose a lot.
In order to shut down false anti-aging claims that are prevalent in the beauty industry.
To shame older people so that they won't be out in society making young people think it is OK to be old, which would mean less funding for aging research.
To make "big pharma" receive corporate subsidies from the government since they can find any molecular change as a druggable target to maximize profit.
To improve nursing home care, if aging is classified as a disease it will mean more doctors in nursing homes which in turn means better medical examinations of the elderly.

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Which of the following alternatives are NOT aging scientists?
Alex Zhavoronkov, Elizabeth Blackburn, George Church
Thomas von Zglinicki, Jay Olshansky, James Kirkland
Freeman Dyson, Richard Dawkins, Noam Chomsky
Sudhir Paul, Alexey Moskalev, Alexei Maklakov
Joao Pedro de Magalhaes, Avi Roy, Attila Csordas

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Who founded a secretive billion-dollar research and development company focused on aging?
Andrea Maier
Deepak Chopra
Salman bin Abdulaziz Al Saud
Bill Maris
Sheldon Adelson

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