LongeCity - Genomics and Aging

The quiz focuses on the relation between genomics as a field, and aging, as a medical problem.

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What is a genome?
A genome is an organism's complete set of DNA, including the most important genes.
A genome is an organism's complete set of DNA, including all of its genes.
A genome is an organism's complete set of DNA, including most of its genes.
A genome is an organism's complete set of DNA, without any of the genes.

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What do “omics” refer to?
Omics refer to the study of genetic information.
Omics refer to the study of information-based systems.
Omics refer to the study of cellular processes in general.
Omics refer to the study of large, comprehensive biological data sets.

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When did the Human Genome Project start and end?
The project began in 1987 and was completed in 2001.
The project began in 1988 and was completed in 2002.
The project began in 1989 and was completed in 2003.
The project began in 1990 and was completed in 2003.

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Which subtype of APOE is most likely to cause Alzheimer's disease?
APOEe4
APOEe3
APOEe2
None, APOE does not impact Alzheimer's disease frequency

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What is the most commonly mutated gene in cancer according to its genomic profile?
p21
p52
p53
p54

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Which of these conditions has shown to accelerate epigenetic aging?
Weaver syndrome
Beckwith-Wiedemann syndrome
Simpson dysmorphia syndrome
Sotos syndrome

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Parkinson’s Disease has been associated with which of the following genes?
PARK2
TCF7L2
BRCA1
MLH1

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What gene is involved in thymic involution?
Sonic Hedgehog
PIP2
Wnt4
L1CAM

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Which of the following genes has been associated with diabetes type 2?
EPCAM
ABCC8
SFARI
SNCA

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As a gene, what does mTOR do?
It turns on autophagy
It turns off autophagy
It prevents telomere shortening
It promotes DNA repair

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Hutchinson–Gilford progeria syndrome (HGPS) is caused by mutations in what gene?
PTEN
CXCL12
GCGR
LMNA

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