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Telomeres

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Mon Jun 15, 2020 4:53 pm

Quiz about telomeres.

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When was telomere shortening first observed?
1950s
1970s
1990s

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Is telomere shortening associated with aging?
not in humans
yes, the connection is well-established
only in germ cells

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How is called the enzyme that regenerates telomeres?
telomerase
telomer-transferase
detelomerase

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How long are telomeres usually in humans?
0.5-2 kb
10-20 kb
90-155 kb

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What organisms have the same telomeric repeat?
all species
all individuals of a given species
none, a telomeric repeat is unique to each individual

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Was telomere length in early life observed to correlate with realized lifespan?
yes, in some species
only if an individual did not reproduce
no

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Are there animal species that naturally maintain telomere length throughout the lifetime?
yes, such organisms have been found
yes, but only handful of rare African carnivores
no, it is not biologically possible

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Can telomerase expression prevent epigenetic aging?
yes
only in specific cells
no

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Is telomere length regeneration crucial for cancerogenesis?
yes, it allows a superb reproduction rate of cancerous cells
yes, too long telomeres are mutagenic and start cancer
no, it is not relevant

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What organism was shown to utilize alternative mechanisms for telomere repair?
M. mulatta
C. carpio
M. myotis

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Can telomere length be affected by lifestyle factors?
yes, especially by exercising and diet
no, it is determined purely by genes
yes, high sexual drive is associated with faster telomere shortening

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What diseases have been associated with shorter telomeres?
flu
depression
none

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Do centenarians seem to have longer telomeres compared to humans with average lifespan?
no, they are actually shorter
no, the same length
yes

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Can telomeres be seen as repetitive nucleotide sequences?
yes
only in their late stage
no

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