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Fight Aging News
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The Longevity-Associated Variant of BPIFB4 Can Be Provided Orally to Produce Benefits in Mice
Proteins are largely quite delicate structures de...
Yesterday, 06:55 PM Read Full Story -
Rejuvenation Roundup October 2025
The trick-or-treaters have all gone home as the l...
Yesterday, 05:00 PM Read Full Story -
Diluting Dietary Calorie Intake with Non-Digestible Fiber Slows Aging in Mice
Researchers here demonstrate that diluting calori...
Yesterday, 11:22 AM Read Full Story -
Amyloid-β Aggregation Disrupts Circadian Rhythm in Supporting Cells in the Brain
A fair sized body of evidence shows that circadia...
Yesterday, 11:11 AM Read Full Story -
Fight Aging! Newsletter, November 3rd 2025
Fight Aging! publishes news and commentary releva...
Nov 02 2025 12:54 PM Read Full Story -
Human Umbilical Cord Mesenchymal Stem Cell Transplantation as a Senomorphic Therapy
Today's open access paper links a number of diffe...
Oct 31 2025 05:54 PM Read Full Story
Articles Archives
Cryonics
Apr 25 2018 10:52 PM |
benbest
in Articles
The following is a quick overview on Cryonics. NB: The information below is periodically reviewed for accuracy, but LongeCity makes no representations or gives any warranties whatsoever that the following information is accurate and complete at an...
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Carbon nanospheres almost double rat lifespan:...
Jul 14 2012 10:19 PM |
ImmInst
in Articles
by AgeVivo and Sven Bulterijs more discussion of the paper in question in this thread in the C60 Health sub-forum this article is a work in progress, it may change over time based on discussions and new information / Introduction In June of 2012...
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Metformin a life extension drug?
Dec 08 2011 11:28 PM |
s123
in Articles
by Sven Bulterijs For hundreds of years it has been known that a plant extract from the French lilac (Galega officinalis) improved the intense urination seen in diabetes patients. From this plant guanidine was extracted but it was too toxic for human u...
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Assessing the effects of c60 on human cancer pr...
Sep 06 2014 11:44 PM |
ImmInst
in Articles
View attachment: c60re02.png "Assessing the effects of c60 on human cancer proliferation in vivo"is led by life-extension trailblazer Kelsey Moody. It is interesting that he turns the attention of his new venture Ichor Therapeutics to...
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"Healthy Aging" is not enough
Feb 09 2013 11:33 AM |
brokenportal
in Articles
A Response to the "Compression of Morbidity" Mindset "...there is no basis for the ardent hopes and positive statements made as to [its] safety and success[..], and [..] therefore, it would be a wrong, whet...
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8 Reasons to reach out to 'the public'
Mar 08 2015 11:34 PM |
ImmInst
in Articles
While the idea that drastic life extension may be an option for humankind in the future has been encountered by many through the media and fiction, the vast majority of the public do not grasp whether and how this could realistically apply to them or t...
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Why do some turtles outlive humans?
Feb 09 2017 12:39 AM |
yoik
in Articles
by Vit Zemanek
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Honorary Member: Fred Chamberlain (boundlesslife)
Apr 04 2013 09:28 PM |
caliban
in Articles
View attachment: fred.jpgIn the early 1970's Fred Chamberlain, together with his wife Linda founded the cryonics corporations Manrise and the Alcor Society for Solid State Hypothermia, The latter continues until today as the Alcor Life Extension Foun...
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Supplement Review: Nicotinamide Riboside
Nov 18 2016 09:58 AM |
s123
in Articles
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crowdsourced multivitamin
Dec 17 2012 01:06 AM |
caliban
in Articles
Extending maximum human lifespan will likely require a wide range of new biotechnology. Powerful interventions such as pharmaceuticals, stem cell technology, and gene therapy are in development but could be years or decades away from widespread impleme...
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Article: Gut microbiome in health and aging
Jan 10 2017 05:59 PM |
s123
in Articles
As part of his new column "Sven's Science Corner" Sven Bulterijs discusses novel insights into the crucial role gut bacteria seem to play in health, disease and aging. ⇒ read the article in "Sven's Science Corner" blog
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Aging theories: Is there a unifying factor in a...
Aug 20 2017 05:40 PM |
ImmInst
in Articles
by: Vit Zemanek
- evolutionary approach to the process of senescence
- programmed theories of aging
- error theories of aging
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Aschwin de Wolf: Cryonics
Feb 19 2017 12:50 PM |
s123
in Articles
(interview Feb. 2017)
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Metformin - a geroprotector?
May 19 2017 07:09 PM |
s123
in Articles
Sven Bulterijs first discussed the potential utility of anti-diabetic substance metformin six years ago on LongeCity. Now Sven returns to the topic with a comprehensive and thoughtful discussion of the recent findings and further background information...
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Nootropics in human trials (Intro)
Sep 09 2017 12:15 PM |
lukas_93
in Articles
by Lukas
Due to further advances in the field of neuropharmacology new possibilities of cognitive self-enhancement emerge.
Some are marketed as ‘smart drugs’, cognitive enhancers or nootropics.
This article aims to provide a brief overview.
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Pioneers: Marquis de Condorcet (1743-1794)
Dec 26 2018 10:36 AM |
G. Stolyarov II
in Articles
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Aging Theories: is an 'aging program' a...
Apr 18 2018 05:45 PM |
ImmInst
in Articles
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Geroprotector Review: Rapamycin and other mTOR...
Jul 18 2017 08:59 PM |
s123
in Articles
Sven Bulterijs continues his discussion of prominent compounds with potential life extension efficacy by looking not just at rapamycin but also at its target, the mTOR pathway, which has likely a key role in mediating lifespan. ⇒ read the article i...
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Antioxidants- relevant for life extension?
Feb 18 2018 11:29 PM |
yoik
in Articles
by Vit Zemanek
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Eternus by Neurohacker Collective
Dec 18 2019 12:46 PM |
ImmInst
in Articles
A 36 Ingredient Formula for Comprehensive Cell Energy & Aging Support
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Crosslinks
Oct 07 2011 12:48 PM |
ImmInst
in Articles
by Johan Sjöberg The diseases and complications of aging are infamous –cardiovascular disease, cataracts, Alzheimer's disease, amyloidosis, cancer, and so on. Their effects are often debilitating, and one of them will always end up causing your death...
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'Nugenics' - breakthrough rejuvenation?
Jun 28 2020 09:45 PM |
Ildathach
in Articles
Discussion of a recent preprint by Horvath/Katcher et al. reporting rejuvenation in mice with an undisclosed blood component.
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Calorie Restriction Primer
Nov 18 2011 08:52 PM |
caliban
in Articles
by Sven Bulterijs & Paul McGlothin, Often described as the only proven intervention that extends mean and maximal life-span in mammalian species, it is also a lifestyle choice for the committed immortalist. But why and how does it work? How to begin...
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Folding@Home Team
Nov 06 2011 07:33 PM |
brokenportal
in Articles
Use your computer's spare processing power to help cure disease!TheLongevity Meme has teamed up with Longecity to contribute to the Stanford Folding@Home distributing computing project – aimed at curing disease through understanding the basics of prot...
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LongeCity Science Initiatives - Autumn 2011 review
Oct 08 2011 12:34 PM |
caliban
in Articles
“To conquer the blight of involuntary death” is a complex task: political, economic, logistic, and social factors all play a role in making this dream a reality. Ultimately though, the challenge remains a scientific and technological one. We need to kn...
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