Through reading a lot of anecdotal feedback on resveratrol, is seems as though joint pain may be the one major drawback to its use.
My question is this: if someone is susceptible to joint problems while taking resveratrol, will that problem ultimately get worse with continued supplementation?
If so, wouldn't that be a huge concern to using it. I mean for one, we don't even know if it extends life in humans for a fact, and secondly; I don't think I'd want to be living with pain for an extended amount of time. Also, this is kinda like CR in that being skinny (having joint pain in the case for resveratrol) can cause biochemical stress responses which may shorten one's lifespan.
Have had joint problems culminating into miniscus rupture two years ago (before taking RES)
In the two years before the meniscus rupture my right knee was burning
sometimes so that I awake in the night from the pain and I had an inflammation
of both knees so that I could hardly go down on them anymore.
About 1 month after surgery I started resveratrol (50% stuff from CL) and it seemed to help.
At least my left knee was completely without any sign of burning/inflammation. Of course the
right keen was in recovery from the surgery and had problems with swelling and an
aggravating feeling. The last two month were without any signs from my knees (for the first time
after years) and I can do everything (soccer, running, jumping, playing with my kids)
While surgery my right knee was diagnosed with grade III chondropathy in the medial
compartment and a very little grade IV defect under the patella.
Currently I'm using 2-3 grams 99% resv per day and successively increased dose.
Within this time I have never had any new inflammation in my left knee and my right
knee recovers to the point where I can't notice any difference to the other one
Edited by notox, 03 September 2008 - 04:47 AM.