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Make you own cheap ubiquinol from ubiquinone and ala?


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#1 Blue

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Posted 28 June 2009 - 09:21 PM


Ubiquinone can be bought relatively cheaply in powder form (as compared to CoQ10 capsules and Ubiquinol in particular):

http://www.iherb.com...-28-g/6107?at=0

While googling about which CoQ10 I found this patent:

http://www.faqs.org/...app/20080226710

"The present invention pertains to the surprising discovery that ubiquinone (CoQ-10) is reduced to reduced CoQ-10 (ubiquinol) in the presence of lipoic acid (e.g., alpha lipoic acid). Ideally, there is at least a molar equivalent of each of alpha lipoic acid and CoQ-10, so that the CoQ-10 is reduced to at least 95% or greater, e.g., 99 to 100%. In particular, a molar excess of alpha lipoic acid is used to help reduce the CoQ-10 to essentially only ubiquinol. In one aspect, one or more fatty acid(s) are included in the compositions. In another aspect, a monoterpene, such as limonene, is included with either the CoQ-10/alpha lipoic acid combination, optionally with one or more fatty acids, or ubiquinol is simply dissolved in the monoterpene, such as limonene, with or without a fatty acid and in the presence of alpha lipoic acid. "

"A major advantage of utilizing lipoic acid with the ubiquinol and/or ubiquinone is in the processing/manufacturing stages. It has been surprisingly found that the lipoic acid helps stabilize the ubiquinol. A stable formulation of ubiquinol is much easier to handle, store and work with because ubiquinol by itself is very easily oxidized and as such, requires very careful precise handling. Special precautions normally need to be taken to make sure that no air/light, temperature changes take place during the processing and manufacturing with the material. With the present invention, the material (incorporating lipoic acid) can be handled just like any fill material and no special handling, processing or storage of the formulations is needed. This is a huge advantage to the manufacturer, especially since ubiquinol is very expensive and degrading it even a little can be very costly."

Alpha lipoic acid can also be bought as powder. Limonene is cheap if bought separately as discussed in another thread.

So if you are already planning to take alpha lipoic acid and CoQ10, if you mix alpha lipoic acid and as Ubiquinone as powder in fatty acids (say olive oil taken with food) and/or limonene (used in capsules to increase solubility), will you then get some Ubiquinol?

#2 rollo

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Posted 22 February 2010 - 07:22 AM

bump

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#3 Johann

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Posted 23 February 2010 - 01:05 PM

bump


If we can make this more aware, then we should see a price reduction in Ubiquinol. It is one or the more expensive supplements.

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#4 Charmion

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Posted 11 April 2013 - 05:28 AM

So how would this work practically? Would just mix some Ubiquinone and ALA and limonene together in a bottle and let it sit a few days?




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