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a few dozen new nootropics as well as IQ genes

nootropics IQ genes

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#1 treonsverdery

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Posted 29 September 2011 - 11:37 PM


Here are some visuals of notes I made about new nootropics. I may type up the 9 or 10 pages soon
typical would be

brain Gooiness affects IQ
diffusion kinetics affect neurotransmitter diffusion at the synapse, brains are gooey, thus the genetics of mucoproteins could actually affect neurotransmitter diffusion rate thus be a source of rapid diffusion kinetics thus be IQ genes. Nootropics may be those pharmaceuticals or peptides that affect cytoplasm viscosity.

Finding high performing cognitive architecture genes
Grab lab mammals with small heads yet high cognitive functionality then compare their genetics with lab mammals of the same species with larger heads with high cognitive functionality. Crossbreed studies will show which genes go with the superiour cognitive architecture as compared with "just having more brain mass" effect. find the similar genes at humans then compare human haplotypes to find the human brain architecture genes that benefit cognition.




Each nootropic is from a 1 minute handyphone note that I transcribed. There are 3 or 5 ish notes per page


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Edited by treonsverdery, 29 September 2011 - 11:47 PM.


#2 Ampa-omega

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Posted 30 September 2011 - 03:05 AM

Sounds very interesting, wow that was a lot to handwrite, i will see if i can read this, a bit hard to interpret your handwriting so if you can type it out that would be great,

non the less a lot of work! thanks for sharing.

and why all the work in this? Are you planing on creating any of these concepts?

Edited by Ampa-omega, 30 September 2011 - 03:07 AM.


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#3 treonsverdery

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Posted 30 September 2011 - 05:29 PM

I thought of a new longevity nootropic like the longevity drug mercaptoethanol where Se replaces S as SE compounds are oncopreventative as well as curative of cancer, then noting that dimethaminoethanol DMAE is a nootropic creating

methySeMercaptoaminoethanol that looks like

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I think finding out what this did with methuselah mice would be nifty.

There is also the centrophenoxine variant of methySeMercaptoaminoethanol where the DMAE like new drug is attached to chlorophenoxyacetic acid which gets it to pass the blood brain barrier. It would be pretty nifty to see if lipophilic as com[pared with hydrophilic versions of mercaptoethanol like compounds caused longevity effects that differed with whether it concentrated at aqueous or lipid areas of the body


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This material like everything I place at imminst.org or longecity.org is public domain

Attached Files


Edited by treonsverdery, 30 September 2011 - 05:39 PM.


#4 treonsverdery

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Posted 11 October 2011 - 12:40 AM

Here are the first two pages typed also at http://groups.google...4558475e9?hl=en#

The genes upstream up the CART (cocaine amphetamine related transcript) peptide may be nootropic IQ genes why are they telling the brain to be more alert (or at least CARTy), if there are say 7 of them, making an animal model of each would perhaps provide a specific link to a gene of noticing "internal" brain state or reactivity to stimuli, if those stimuli are cognitive at the brain rather than sensory then these upstream of CART genes are linked to cognition. Natural variations like haplotypes could then be verified at human population to go with various cognitive styles or capacities Thus are cognition architecture genes as well as IQ increasing genes
I have read that womens ability to detect various scents is ten times higher at particular times of the month, I have also read that SAT scores vary 10 or 20 prct with time of the month, I have also read that estrogen is a mild cognitive enhancer thus the genetics of the distribution of estrogen receptors at particular areas of the brain localized to go with cognitive effects (Neocortex, hippocampus) as well as their haplotypes are higher iq genetics
CSF Dura matter development genes as well as ions cytokines at various ages describe possible wellness or longevity profiles along with cognitive effectiveness chemical ratios as well as suggest possible IQ beneficial genetics. I think Ive previously described this

Mapping the production of messenger RNA mRNA throughout the brain as well as body is accomplished with quantumn linked photons of different colors Basically I have read things at New Scientist where a quantum linked photon pair creates one photon that goes through an opaque area then is absorbed with a unique shape object The quantum benefit is that the linked photon at a different transparent detector space traces a 3d outline of where its linked friend goes. Actual data of Nifty imaging at a distance. We just apply that to color absorption of chemicals looking for uniques with something like quantum linked IR spectroscopy then use it on neural tissue to describe what brain chemicals are doing what where when people think particularlly well to find optimal brain chemistry as well as structure. First visualize a leaf The ratio of GG' YY' absorption describes where the chlorophyll is at with a raster trace. Then give it light n glucose to see active change. Then use the same system on neural tissue using the frequencies of IR spectroscopy to find what chemical or protein is doing what where when people think. (green green prime linked photon pairs, yellow yellow prime linked photon pairs
) GGYY The green n yellow photons reflected absorbed reflected at a raster path along a leaf is measured with the quantum linkage noting that chlorophyll reflects green the YtoG ratio describes where at the leaf chlorophyll is actually present Now applying this to the human body we use quantum linked photon detection ratios at the IR spec absorption frequencies of particular brain chemicals like neurotransmitters or proteins although eentsy (millions of mRNA per moment) It may be possible to detect particular mRNA (or radiolabelled thus ir spectroscopically very unique) activity this way or even record a ribosome actively travelling on on a nucleic acid as the absorbability of a quantum linked photon at a radiolabelledribosome could oscillate going wom wom wom as the ribosome visited the notably different nucleic acid shapes giving a listing of what mRNA were being actively transcribed at particular brain areas thus linking gene activity to neuroanatomic area with area neurostructure linked to function Particularly mapping what occurs during a human mind during particularly effective moments of cognition, mapping aha moments. or active complex yet perceptually notable activities when thought is particularly content full as well as cogtnitively rich (as compared wiuth just rapid or responsive)
People haqve been measured to be more cognitively able at different times of day NMR detection of ribosomes (or radiolabelled ribosomes) oscillating as they glom different nucleic acid sequences links protein activity to area as well as notability of awesomeness of a thought at a particular time thus finds IQ genes from the dna that produced the measured mRNA that are cognition genes of thought structure type as well as brain locality
I think that Lassitude of a warm day is different than a warmed blood effect on the CNS. Finding the cytokines that communicate either outside CNS like afferent of sympathetic nerves that bring the cognitive shift then downregulating these lassitude cytokines chemically is a nootropic as well as a cure for warmth lassitude effect As an IQ gene the genetics of the cytokine source of warmth lassitude may have different haplotypes to navigate as well as cytokines genes to modify It is even possible that as this is an outside CNS effect that there is even an anesthetic that is acually a nootropic.
I have read psychology studies of intent where the Voice of purpose processes acknowledgement of purpose anywhere from .1 second to a few seconds after an actual action, Now think of the stimulus reward cycle of some psychology research, There may be haplotype differences among measured human intervals of purpose that would more tightly link action to purpose strongly effecting reinforcement learning or active knowledge of material. The published difference between the interval of purpose compared with the moment of action may affect the rate as well as linkage of actions to learning Finding those persons with very tight rapid links between actopurpose may be finding persons with highresponsiveness to reinforcement learning thus the genetics of the interval of purpose may be IQ beneficial genes Or possibly people with wide intervals yet high learning may have a genetics of cognitive breadth conferring wisdom or nonconscious consideration of multivariate material. It is possible widely screening chemicals to see if the effect purpose interval may create new learning hyperreadiness drugs or possibly artificial wisom (mulling) drugs
Grab lab mammals with small heads yet high cognitive performance then crossbreed them with large head high cognitive performance mammals of the same species to find the architectural brain structure genes that cause high performance as distinguished from just more brains then create the normosomatic large headed version with the higher performance architecture at humans to give higher IQ Note giving girls estrogen blockers or delaying puberty during the growth phase of bones causes larger skull volume as well as larger brain size along with super female cognition to brain mass ratio while happening to make the girls taller thus puberty at 14 or 20 would be a nootropic or IQ gene also as estrogen is a cognitive enhancer puberty could be restructured to be cognitively beneficial as well as the new socioreproductive option zone puberty represents So, that sounds iffy yet basically says, delaying puberty a few years might give girls 20 to 40 points more IQ based on volume increase prior to estrogen cued ceasing of bone growth. Since they are cogitively equal at a different brain size at age 20 having equal brain size would give girls then women cognitive advantage.
Peptidases (as well as restriction enzymes) divide peptides at particular places which causes the predictable creation of particular protein fragments or peptides, some of these are drugs Genetically engineering new peptidases or doing adenovirus transfection at neurons causes the division of naturally occuring ordinary peptides to create new nootropic active fragment peptides similar to CART, vasopressin, AEDG, nonthyroid active Thyroid peptide fragments, Kappa opoiod placeholders, that give active cognitive benefit Genetically engineering peptidases specific to what might be called preexisting antinootropic peptides could remove baseload of antinootropics causing greater cognitive capacity Also peptidases that that affect glycosylated junk or glyucoproteins could reduce cumulative junk (I think that may have been researched) This is a way to create entirely new ntelligence genes making them a part of the human genome.

(thats the first 2 pages of 9)

Edited by treonsverdery, 11 October 2011 - 12:40 AM.


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#5 treonsverdery

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Posted 11 October 2011 - 11:55 PM

Ive seen a graph (huttenlocher 1991) that says that babies that hear lots of words can learn speaking words nine times as rapidly Find a lab mammal that shows a similar effect at a different task then find the mRNA that goes with a strong genetic ability to have this nine times more rapid absorption then repeat ability effect The genes that code those mRNAs are thus IQ genes nootropics from siRNA are also possible

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Mice have highly rapid physiochemical responsiveness, if a mouse body waited as long as long to react to a pimple as a human bofy then the pimple size would be vast or dangerous as related to body volume What is the source of the rapidity of this response to variously immunogenic compounds or perhaps any cytokines. the source of that rapidity could then be applied to neurons as well as cytokines as well as regeneration rate possibly maintaining superpeak mental freshness.

Nerve conduction velocity is linked to IQ what mammals have the highest nerve conduction velocity those gene differences brought to humans are then IQ genes Further I think nerve conduction velocity may vary with normal physiocurvature what persons are ar the 999th percentile of nerve conduction velocity at different physicaly normal nerve curvatures.

learning a musical instrument is published as raising IQ Time to create a different microphysical activity that brings similar benefit. it is possible that a computer keyboard or mouse application could have the similar arbitrary continuously improvable performance effect of an instrument thus would gradually raise nervous system ability then IQ with continued use Further the emphasis on keyboard menu commands creates higher software fluency while raising IQ This is an opportunity to raise both fluid ability as well as applied knowledge simultaneously


A studyquality raising raising textbook cover could have a camera as well as an LED with sound ability The software would note when the persons view was actually attentive to the text as well as look for microbodylanguage of comprehension then respond thus minimizing spaceout of "zombietravel" reading Similarly it is possible that a pleasing reward sound could occur if the person actually wrote a side note using some of the same words or symbology of the text particularly beneficial when studying math as well as science thus demonstrably causing equation practice The light up event could also be a reminder to have the person review at their mind what was read possibly also detecting the body language of mental eview to verify.

sleep is published as potentiating long term memory People or lab mammals could be measured to find the upper thousandth of higher percentile of this effect then then the genes that go with this physical process be identified Nonhuman mammals crossbred then genome compared are a rapid approach The genes as well as the cytokines they code are IQ genes as well as nootropics cytokines of memory ability could be addressed as either peptide proteins to be described as new codon sequences that create new momory genes as well as possibly siRNA modulation effects, chemicals, or even as genes

Ive read there are more than 30 published neurotransmitters as well as receptors Comparing the versions of these betwen widely different species like placental to nonplacental mammals could provide a wide variety of the chemical neurotransmitter variants as well as gene variants that cause superior performance Thus giving new IQ genes as well as nootropic chemicals Octopamine <-> dopamine is one version of a distant species neurotransmitter analog effect

Researchers on immanent death hyperconsciousness phenomena nonlethally reproducing that state then measuring mRNA cytokines as well as genetic differences creates genetics of supercomprehension as well as new nootropics

Ribosome genes are spread throughout the human genome there may be copy number variations as well as neighboring sequence location variations that effect the actual production of the amount of ribosomes at particular physical body areas Noting that ribosomes are the protein makers of the body these natural genetic variations may affect CNS responsiveness, healing time, nerve resilience, memory chemical production thus are generally well being IQ genes as well as as neurodevelopmental area specific nootropics

Thyroid hormone is linked to rapid thought, rapid movement as well as skinniness Noting that thyroid hormone is a protein there may be nonthyroid active peptide fragments that are nootropic active these little fragments are also codon producible peptides thus could be redescribed as new IQ genes that produce active peptides.

Edited by treonsverdery, 12 October 2011 - 12:04 AM.





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