Ever since adding Guanfacine 1mg, taking Adderall XR 20mg has given me very positive effects without the mind racing and increased heart rate.
I find I only need 8 hours of sleep, I have more control over my impulses, and for the first time in my life I can pay attention without effort. Fatigue, lethargy, anhedonia are all gone. No longer am I glued to the bed or needing to blast music throughout the day so as to not doze off. If this is how "normal" people function, boy have I been missing out.
Now being a budding pharmacologist and a long time reader of nootropic forums, I know all too well of the seriousness of TOLERANCE. And for this reason I am very scared of continuing with the Adderall. I am not considering adding an NDMA antagonist because I don't want impaired memory. I will do magnesium though.
I don't want to restate a question that has been asked hundreds of times on the internet but I will spin it a little differently with a more theoretical twist. Suppose that I am ADHD. Some research says that this is because of faulty catecholamine transporter genes. So my DA and NE is for whatever reason not being released at optimal levels. Adderall causes release of more of these neurotransmitters and so my receptors respond by down regulating. But if my receptors were never recieving the optimal amounts anyway, why would they down regulate? The point is shouldn't Adderall over time reach an equilibrium that is above what my natural baseline is due to faulty transport?
I don't want to lose the focus and energy Adderall gives me. I don't care about euphoria or other recreational considerations, I only want to retain the improved focus. Is it wise to be using Adderall every day for this purpose? One fear is that I will return to baseline eventually but now with a crash.