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[OpenStrife]

A good majority of the Pram topics I have read say that taking it with food will give you the most effective results.....
(Using water soluble Pramiracetam Monohydrate)
The first 2 times I took it, I did it about 1-3 hours after eating. Sometimes with a choline source, sometimes the choline source was with the food(a few hours prior).

Now, the first time I tried to take my Pram with food and choline, I did not feel my normal pram effects. I actually felt drained, tired, on the border of depression. Usually when I simply eat food in the morning without taking a substance I feel great. But it seemed taking Pram with food was having a counter effect. I

About 3 hours later after my food was digested and I never even began to feel any Pram effects... I decided to take Pram on an empty stomach with some extra choline. Allo and behold in under 10 minute I begin to feel it's wondrous effects that I had experienced the first 2 times I took it hours after eating.

I have read before that people mixing Pram with substances(outside of the body), can cause it to react and turn into odd substances. Is it reasonable to say that mixing Pramiracetam Monohydrate with food in your stomach before the food is digested can react negative with the pram causing it to become ineffective? This is the only plausible idea I can think of.

Or one could say that 'everyone is just different'.... but that wouldn't explain why taking it with food didn't allow me to feel any effects even in 3 hours.

One of the primary indicators that I know Pram is taking effect is my stomach begins to stir a little, as if my body is increasing digestion. Which increased levels of acetylcholine cause increased digestive juices, digestive tract force, etc. It's one of the more physical positive side effects that let me know it is working.

What do you all think? Why does everyone say to take Pram with food, but it only works for me if I take it without food?

Another possible idea I had is that Pram could be reacting with the pure whey protein I take with my meals, when usually that protein isn't in that form until it has been absorbed into the blood. Could pram be reacting with it?


I always have so much to say when my brain is reved up like this . Post your inputs! Every reply teaches me something and gives me ideas to work with

Edited by OpenStrife, 21 June 2012 - 06:15 PM.

[Baten]

I always took pram with fish oil on an empty stomach. Idea was that absorption is better on an empty stomach, and pram is fat soluble as far as I know so it mingles well with the fish oil.
If you absorb it better without anything at all (with water?) feel very free to do so, everybody is indeed different; no need to be hard set on doing it "like the others do".
I personally think everything should be taken on an empty stomach unless it causes you stomach upset, even if the container (or forums) tell you to take it with food.