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Cerebrolysin + (other Nootropics) EXPERIMENT!

cerebrolysin

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#1 Billybear185

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Posted 27 March 2014 - 09:52 PM


Hello Forum!!!

Tomorrow I should be getting my Cerebrolysin from anti aging systems. I purchased 10 x 5ml ampoules, and I also purchased 12 x 10 ml ampoules from superhuman gear, but that will probably not be in for the next week or so. Over the next few weeks I will post everyday on my experience, both objective and subjective. The objective will probably be some type of test on luminosity, especially dual n-back, which is really the only game on luminosity that has alot of credibility. For the subjective I will try to rate my overall mood from 1 to 5 (1 to 10 seems kind of pointless), as well as other subjective factors.

First I would like to state what I propose my stack to be, and feel free to add any suggestions.


Every day (for 10 days) I will take the following:

1) 5ml of Cerebrolysin 1x day injected into my right quad.
2) ~ 800 mg of piracetam 2x day
3) ~ 500 mg of cdp choline 2x day
4) 1 gram of fish oil 2x day

Any suggestions are welcome, but I don't want to make this stack too complicated because 1) I don't see the point and 2) there will be too many variables involved.




I should also add a few things about myself primarily so people reading can draw their own conclusions. I am 21-years-old, in college, majoring in Integrative Neuroscience and Biochemistry. I drink fairly often, but obviously not for this experiment. I also smoke weed almost everyday, on and off, but again I will not be during this 10 day experiment.
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#2 Billybear185

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Posted 28 March 2014 - 03:53 PM

Alrighty, just got my package in the mail. I will actually be taking 10 ml the first day just because I am so eager. Also if people could bump this topic, so my results can be more easily viewed that would be great.

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#3 Billybear185

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Posted 30 March 2014 - 12:15 AM

I took 10 ml again today, but unfortunately I got massively drunk yesterday. Therefore, it might take a couple days to notice the effects. I will update again tomorrow, but for now I don't think I will be noticing any improvement for a couple days.

#4 FW900

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Posted 30 March 2014 - 01:49 AM

I took 10 ml again today, but unfortunately I got massively drunk yesterday. Therefore, it might take a couple days to notice the effects. I will update again tomorrow, but for now I don't think I will be noticing any improvement for a couple days.


Not to be condescending, but "getting massively drunk" is probably the worst thing you can do during a period of experimentation as it will hinder your ability to determine the efficacy of a nootropic. (Then again... it might be good for testing if it improves your impaired memory whilst drunk) Ethanol has been found to have a negative effect on memory formation and even a low amount has been found to impair LTP related processes which are crucial for learning. Cutting back on alcohol might not be a nootropic in and of itself but, it will definitely be beneficial for your memory.

http://www.ncbi.nlm....pubmed/24385131
Findings suggest that enhancement of extrasynaptic GABAAR-mediated tonic inhibition and/or reduction of NMDAR-mediated neurotransmission by EtOH blocks LTP-like plasticity in human cortex at very low doses that are easily reached during social drinking. Therefore, low-dose EtOH may jeopardize LTP-dependent processes, such as learning and memory formation.


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#5 Billybear185

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Posted 30 March 2014 - 02:29 AM

Why is that condescending? It was very stupid of me to get massively drunk. The only reason why I drank was because it was my 21rst and I wanted to have a beer at a bar with my father. Fortunately there are no events coming up that I will be tempted to drink.
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#6 PWAIN

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Posted 30 March 2014 - 11:35 AM

Happy 21st!!!
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#7 Billybear185

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Posted 30 March 2014 - 07:14 PM

Alright... Today I took all my regular nootropics and 5 ml of cerebrolysin. I can not say I feel anything easily noticeable, but I will mention the subjective effects. Also, I am going to wait to test myself on lumosity until the last day of the experiment.

As far as the subjective effects go I have noticed a calmness, but this may be due to everyone else on here mentioning it. I forgot to mention, in addition to my other drug habits, I take a lot of stimulants. I have coffee 2 to 3 cups, atleast, everyday, in addition to vyvanse a few times per week. For the last 3 days I have not had any coffee or vyvanse and I am surprisingly not exhausted as I normally would be. I did, however, have a minor headache this morning, but nothing like I would expect, or have had in the past from caffeine withdrawal. Today, my mood scale from 1 to 5 is a 4.


Hopefully, I will notice the extreme effects I have read about in the next couple day (fingers crossed).
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#8 Billybear185

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Posted 30 March 2014 - 11:27 PM

Does anyone think it would be a good idea to add a B Complex in the mix?

#9 Billybear185

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Posted 31 March 2014 - 10:04 PM

Today I took 15 ml of cerebrolysin, along with the other supplements I am already taking. I planned on only taking 10 ml, but my suitemate wanted to watch an injection procedure, so I did another 5 ml. As for the subjective I noticed I am much happier and focused. I often look around frequently when I am working or studying, but on cerebrolysin I am much more focused on what I am doing. I also notice a sense of calmness. Unfortunately, to be perfectly honest, we have all had clearity days such as this and we are never able to target why we feel as good as we do. Therefore, as of now, I don't want to credit it to the cerebrolysin. Today my overall mood level is a 4 out of 5 on the scale. Tomorrow I will only take 10 ml.

#10 Billybear185

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Posted 01 April 2014 - 10:31 PM

Day 3 (technically)

Today was a great day in regard to the subjective effects of the cerebrolysin (10 ml today). Lets walk through the day...


I woke up at approximately 7:30 AM to go work out. I got back around 8:30 and injected 5 ml of cerebrolysin into both legs. I was a little tired from only 6 hours of sleep and my morning exercise, so I took a 45 minute nap (don't worry this is relevant). During this 45 minutes, or atleast towards the end, I dreamt more vividly than I have in a long time. At one point during the dream I dreamt I woke up and returned to my regular routine, yet I was still dreaming. That's when the dream felt very real. I mention this because REM sleep is highly correlated with non-declarative memory, thus the cerebrolysin did something.

Through out the rest of the day I felt a calm, yet focused feeling. Probably the most pronounced aspect of my mood was a huge reduction in any form of anxiety, almost indifference in relation to situations with other people. Today my overall mood level is 5 out of 5.

When studying for Organic Chemistry I noticed I could more easily categorize and find relations between ideas, however I did not try to absorb much information, so this factor is highly subjective.


As a whole the experiment is going great, I just hope it is not all in my head, so to speak.

#11 Billybear185

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Posted 03 April 2014 - 12:11 AM

Day 4


Dose: 15 ml of cerebrolysin + other nootropics from first post.

Today was not as great as yesterday. All the effects I felt yesterday were about the same today, except I felt no motivation to achieve anything. I felt calm and relaxed throughout the day, but every time I went to focus on something, I lost interest. I should also add, though insignificant, I did have a very small amount of wine last night, about 3 to 4 oz worth. I had to have a nice chianti with my breaded chicken and assorted olives, ofcourse. Though I could absorb information pretty easily my brain seemed to be moving more slowly and I did not care about the information being learn. In this case I was studying organic chem, which I usually find somewhat interesting.

The reason why I injected 15 ml is because after injecting 10 ml, I felt nothing significant, so I did 5 ml more about 6 hours later. Today I would rate my mood at 3 out of 5.


If anyone has any suggestions as to what might be going on please respond!!!

#12 Billybear185

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Posted 04 April 2014 - 01:35 AM

Day 5

Dose: 10 ml cerebrolysin + other nootropics

Today was positive overall. Much better effects than yesterday. Today I was able to think more clearly about the information I was trying to study. My working memory was also noticeably better. However, the most noticeable effect of the cerebrolysin, most likely the cerebrolysin, is its anti anxiety, anti depressive qualities. In addition, I don't feel much of an urge to smoke pot or drink. Before this I always had the urge to either drink or smoke pot, but luckily the cerebrolysin greatly diminishes this urge. I also noticed that I have a better ability to visualize things. I noticed this when trying a technique known as 'image streaming' as well as during meditation. Today my overall mood was a 4 out of 5.

Tomorrow I will only inject 5 ml, and then I might take a couple days off.

#13 Godof Smallthings

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Posted 04 April 2014 - 02:58 AM

If you are not doing it already, get your daily 40 min of dual-n-back going now while you have the cerebrolysin! Excercise that executive function and attention muscle.

Brain Workshop is free.
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#14 Billybear185

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Posted 04 April 2014 - 02:00 PM

If you are not doing it already, get your daily 40 min of dual-n-back going now while you have the cerebrolysin! Excercise that executive function and attention muscle.

Brain Workshop is free.


That is a very good idea. I use lumosity, which cost money, but they have many other games than just just dual N-back. Although dual N-back is the only one that has the evidence to back it up.

Just a quick update. I only took 5 ml this morning and I will make note of the effects and update this post in the afternoon.

#15 lourdaud

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Posted 04 April 2014 - 02:45 PM

Sounds good!
You could check out tDCS and neurofeedback as well. Or simple meditation, that one's free after all.

Edited by lourdaud, 04 April 2014 - 02:46 PM.

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#16 Billybear185

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Posted 04 April 2014 - 03:34 PM

Sounds good!
You could check out tDCS and neurofeedback as well. Or simple meditation, that one's free after all.


I have an eeg machine from emotiv and I am getting into neurofeedback soon. I just have alot on my plate with my double major in neuroscience and biochem.
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#17 Billybear185

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Posted 05 April 2014 - 01:19 AM

Day 6

Dose 5 ml

Today started off well as in any other day. However, late in the day I started to get really bad headaches. I still have one as I write this, so tomorrow I will not be injecting cerebrolysin, but will continue with the other nootropics. I know that the half life of cerebrolysin isn't known because it is endogenous to the human body, so I may have built up a large amount in my system. Today I would rate my mood as a 2 out of 5.

#18 lourdaud

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Posted 05 April 2014 - 02:15 AM

Day 6

Dose 5 ml

Today started off well as in any other day. However, late in the day I started to get really bad headaches. I still have one as I write this, so tomorrow I will not be injecting cerebrolysin, but will continue with the other nootropics. I know that the half life of cerebrolysin isn't known because it is endogenous to the human body, so I may have built up a large amount in my system. Today I would rate my mood as a 2 out of 5.


I'd stop the piracetam and CDP choline instead. Don't think I've seen any reports of CRB headache but those other two are notorious for causing headaches.
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#19 Billybear185

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Posted 05 April 2014 - 02:33 AM

Day 6

Dose 5 ml

Today started off well as in any other day. However, late in the day I started to get really bad headaches. I still have one as I write this, so tomorrow I will not be injecting cerebrolysin, but will continue with the other nootropics. I know that the half life of cerebrolysin isn't known because it is endogenous to the human body, so I may have built up a large amount in my system. Today I would rate my mood as a 2 out of 5.


I'd stop the piracetam and CDP choline instead. Don't think I've seen any reports of CRB headache but those other two are notorious for causing headaches.



Yeh I agree that what your saying makes sense, but I have never got a headache from piracetam and choline before, so I think I will lower my dose of 'other nootropics, and stop the cerebrolysin for a couple of days.

#20 Billybear185

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Posted 06 April 2014 - 03:14 AM

Today I just took a lower dose of piracetam, but kept the fish oil the same, and did not take cerebrolysin. The effects of cerebrolysin definitely carried over from the previous day. Today I read my necessary reading for neuroscience, and the information seemed much easier to absorb, relatively. My ability to focus is also greatly improved, and my ability to make good decisions has improved. I will not make an update tomorrow, as I am not going to take cerebrolysin again until Monday. At which time I will take 10 ml for 5 consecutive days. In addition, I will try to make my next post much more detailed. My overall mood was about a 3 out of 5 today.

#21 Maxpower

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Posted 06 April 2014 - 05:09 AM

Billybear. Have you tried any more complex nootropics stacks previously?
I am just wondering how Cerebrolysin compares with fairly complex stacks (inludes Alpha,Pram, oxi, sulb, PRL 8-53, Suni, Coluracetam) either by itself or as an addition. My complex stack works well, just wondering how Cere compares?

#22 Billybear185

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Posted 06 April 2014 - 04:39 PM

I have tried all the racetams, including noopept, but the racetams are a completely different category of nootropics. The racetams, most likely, work on autoreceptors that speed up the metabolism of the brain. I have also tried lions mane, which is in the same category as Cerebrolysin, yet far less potent. I have also tried a range of acetylcholinesterase inhibitors, such as Huperzine A and Galantamine. The AChE inhibitors did not increase declarative memory, but did increase non-declarative memory, such as events in time. However, these drugs have a few bad side effects.

Now on to Cerebrolysin!!! Cerebrolysin, atleast for me, is far more potent than the previous nootropics I have mentioned. All the other nootropics I have tried either lost their efficacy, or they worked far less effectively. Cerebrolysin essentially grows new brain cells, the solution is full of proteins and Neural growth factors. With out a doubt this drug has changed my ability to think fluidly and focus with a calm demeanor. I am starting another cycle on Monday, watch for my updates.

#23 Logic

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Posted 08 April 2014 - 12:21 PM

I noticed that you seemed to feel best a day after taking 15mg...



#24 Billybear185

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Posted 08 April 2014 - 07:18 PM

I have not updated like I said I would, but that is because I was not feeling well yesterday. Unfortunately, when a few people get sick around the University it soon spreads everywhere. I am feeling alot better today, but nothing really new, assuming I feel much better tomorrow I will give detailed feedback. 



#25 Billybear185

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Posted 10 April 2014 - 09:35 PM

It has been a long time since my last post, so I have quite a bit to talk about. First off, just to reiterate, I have been taking 10 ml of Cerebrolysin by intramuscular injection every morning, as well as 4 grams of fish oil per day and about 2 grams of piractam (I took out the choline it wasn't necessary). 

 

There are two effects of the Cerebrolysin that are most noticeable. One is its antidepressant like properties, which I can claim without a doubt, especially with the amount of stress I have been under lately. Second, and this probably only pertains to personalities such as mine, Cerebrolysin makes me far less compulsive to drink or smoke weed. I have not smoked since I started the Cerebrolysin, and I only drink very small amounts, mostly because I am a bit of a wine snob. Unfortunately, atleast for deducing results, this lack of drinking and smoking might explain my improvements in other areas, such as working memory, verbal fluency, concentration, lack of paranoia, and so on.

 

That being said there were many other improvements, yet they were a little more subjective. Again, my ability to concentrate without having irrelevant thoughts enter my mind was greatly improved. This may be a bit of a stretch, but my energy levels seem to be much higher. This may also be due to the fact that I am drinking far less, which of course takes a toll on the mind and body.

 

I should also add that I am exercising a bit more than I usually do, but I have always been an active person, so this probably explains my well being to a very small extent. However, my sleeping and eating patterns are relatively the same.

 

I have decided to take a few days off from the drug and on Tuesday the 15th I will be doing a 10 day straight course of 10 ml Cerebrolysin injections. I promised you guys that I would supply more objective measures of cognitive ability, which I have not. Therefore, I will be taking some time off and take some pre experimental measures through lumosity, mostly dual N-back, and post them daily starting next week. I unfortunately did not get to these measure. I think I was just excited about the results I was getting.

 

 

As an end to my writing I want to say that in the future I plan on doing intravenous therapy with Cerebrolysin. I know I know most everyone is adamantly against such a method, but I am going to research it for atleast a month before I consider trying it on myself. If at the end I still do not feel comfortable after watching numerous videos and auditing nursing classes at my university, then I will just pay off one of the senior nursing students, who I trust, to do it for me.    


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#26 jroseland

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Posted 06 September 2017 - 12:02 PM

Do you have any photos of Cerebrolysin from anti aging systems that you can post?

As an end to my writing I want to say that in the future I plan on doing intravenous therapy with Cerebrolysin. I know I know most everyone is adamantly against such a method, but I am going to research it for atleast a month before I consider trying it on myself. If at the end I still do not feel comfortable after watching numerous videos and auditing nursing classes at my university, then I will just pay off one of the senior nursing students, who I trust, to do it for me.    

 







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