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Practical whole-tooth restoration utilizing autologous bioengineered tooth germ transplantation in a postnatal canine mo

tooth restoration okayama university

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#1 alc

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Posted 20 March 2017 - 12:30 AM


First whole-tooth regeneration in a large animal:

 

http://www.nature.co...icles/srep44522

 

"In this study, we demonstrated successful tooth restoration by autologous transplantation of bioengineered tooth germ into a tooth loss region in a postnatal canine model. We also determined that the bioengineered tooth erupted into the oral cavity with the features of proper tooth tissue formation and restored physiological tooth function, such as the response to orthodontic mechanical force. This study represents a substantial advancement in organ replacement therapy through the transplantation of bioengineered organ germ as a practical model for future whole-organ regeneration."






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