I have trialed fluvoxamine for a few days. The sides were too much to handle for me, nausea, 3 - 4 hours after dosing somnolence, muscles were achy and heavy. Overall I've felt worse than ever. And this was with just 25mg. Could also be related to dropping caffeine for the treatment, because of hepatic inhibition of caffeine clearance induced by fluvoxamine.
Which points me to either it being somewhat sigma-ergic in nature (fluvoxamine is a potent sigma agonist). Now I've felt some positives (stronger eye contact), but the dysphoric effects were just too intense and i've nixed it for now.
Would sertraline be a better fit (with it's sigma antagonism)?
Edited by vader, 28 March 2017 - 06:52 PM.