10 replies to this topic

[Skyguy2005]

Does anyone know about hops extract supplements? It seems to be surprisingly rare - considering basically it is to beer what resveratrol is to red wine - I could only find this:

 

https://www.healthmo...mplex from Hops

 

I enjoy hop tea, and of course, beer, but it seems it has not been researched enough to be a hot supplement?

[Iuvenale]

I've taken it for a few years. I get it at Swanson's. https://www.swansonv...FYkBaQodmG8B5Q 

Compound from hops lowers cholesterol, blood sugar and weight gain

 

CORVALLIS, Ore. - A recent study at Oregon State University has identified specific intake levels of xanthohumol, a natural flavonoid found in hops, that significantly improved some of the underlying markers of metabolic syndrome in laboratory animals and also reduced weight gain.

The findings were published in a special issue of Archives of Biochemistry and Biophysics that was focused on "Polyphenols and Health," and they suggest a possible new approach to issues such as human obesity, high cholesterol and elevated glucose.

Combinations of these problems, collectively known as metabolic syndrome, are linked to some of the major health issues and causes of death in the developed world today - especially cardiovascular disease and type-2 diabetes.

In this research, laboratory mice were fed a high-fat diet, and given varying levels of xanthohumol. Compared to animals given none of this supplement, the highest dosage of xanthohumol given to laboratory rats cut their LDL, or "bad" cholesterol 80 percent; their insulin level 42 percent; and their level of IL-6, a biomarker of inflammation, 78 percent.

Because they were still growing, eating a rich diet, gaining weight and becoming obese, the weight of the lab animals increased, but by 22 percent less in those receiving xanthohumol, even though all animals ate the same amount of food. Intake of xanthohumol appears to increase their oxygen consumption and metabolic rate, with implications for weight control.

"This is the first time we've seen one compound with the potential to address so many health problems," said Cristobal Miranda, a research assistant professor with OSU's Linus Pauling Institute and lead author on this study. "These were very dramatic improvements."

More research will be required to show safety and efficacy in humans, the researchers said.

"Work is still needed to further demonstrate the safety of high doses of xanthohumol, but dosages 15-30 times higher than we used have already been given to animals with no apparent problems," said Fred Stevens, a professor in the OSU College of Pharmacy, principal investigator with the Linus Pauling Institute, and corresponding author on the research.

"After further study, this might provide an effective treatment for metabolic syndrome at a very low cost."

This study for the first time also identified one of the mechanisms of action of xanthohumol - it appears to decrease plasma levels of PCSK9, a protein that plays a role in cholesterol levels. Lowering levels of PCSK9 should increase the clearance of LDL cholesterol from the blood.

Metabolic syndrome is defined by clinical diagnosis of three or more of several conditions, including abdominal obesity, elevated lipids, high blood pressure, pro-inflammatory state, a pro-thrombotic state, and insulin resistance or impaired glucose tolerance. About 25-34 percent of the adults in the United States meet these criteria, putting them at significantly increased risk for cardiovascular disease and type-2 diabetes.

Direct health care costs arising from obesity or related disorders account for up to 10 percent of U.S. health care expenditures, the researchers noted in their study.

Xanthohumol has been the subject of considerable research for its potential health benefits, as have other flavonoids such as those found in tea, garlic, chocolate, apples and blueberries.

Xanthohumol is found naturally in hops and beer, but the highest level used in this research was 60 milligrams per kilogram of body weight per day. This corresponds to a human equivalent dose of 350 milligrams per day for a 70-kilogram person, which far exceeds any amount that could be obtained by ordinary dietary intake. A level that high would equate to a beer intake of 3,500 pints per day for a human adult.

However, that amount of xanthohumol could readily be obtained in a dietary supplement that could be taken once a day.

 

[boylan]

Fairly recent study on xanthohumol and PKA inhibition https://www.ncbi.nlm...pubmed/28122154

[aconita]

Compound from hops lowers cholesterol, blood sugar and weight gain

 

....and blocks testosterone.

http://www.newswise....prostate-cancer

 

Hops is one of the strongest phytoestrogen known, while xanthohumol blocks estrogen too an hops extract might contain 8-Prenylnaringenin which is damn estrogenic.

 

I would stay well away from hops and its extracts....unless you like to grow big boobs (and prostate), of course.

[Baten]

 

Compound from hops lowers cholesterol, blood sugar and weight gain

 

....and blocks testosterone.

http://www.newswise....prostate-cancer

 

Hops is one of the strongest phytoestrogen known, while xanthohumol blocks estrogen too an hops extract might contain 8-Prenylnaringenin which is damn estrogenic.

 

I would stay well away from hops and its extracts....unless you like to grow big boobs (and prostate), of course.

 

 

My sleeping aid has 80 mg of Hops extract, so for 3-4 tablets it has 240-320mg of Hops extract. Do you reckon it's harmful?

[aconita]

As said I will stay well away from hops in any amounts, a beer some now and then is all I would consider unlikely to play a significant role.

 

By the way beer wasn't originally intended to contain hops, it is a much later add which has to do with religion since it suppress sexual desire.

 

I can't see any reason why a sleeping aid should contain hops in any form or amount, to prevent spontaneous nocturnal hard ons to wake one up maybe?    

[Baten]

As said I will stay well away from hops in any amounts, a beer some now and then is all I would consider unlikely to play a significant role.

 

By the way beer wasn't originally intended to contain hops, it is a much later add which has to do with religion since it suppress sexual desire.

 

I can't see any reason why a sleeping aid should contain hops in any form or amount, to prevent spontaneous nocturnal hard ons to wake one up maybe?  

 

Hops have traditionally been used as a sedative used to lessen anxiety and increase sleepiness. Most hops-related sleep studies with humans pair the extract with valerian and prove that, when taken together—usually 120 mg of hops extract with 500 mg of valerian extract—the combination may help to improve sleep and decrease the time it takes to fall asleep. That said, there is no research that separates the effects of hops from the valerian and so it is unclear if hops are effective on their own as a sleep aid.

→ source (external link)

 

I guess it worked its way into sleeping supplements with no clear indication that it's actually useful. Won't buy again! Thanks

Edited by Baten, 14 June 2017 - 06:35 AM.

[Skyguy2005]

 

Compound from hops lowers cholesterol, blood sugar and weight gain

 

....and blocks testosterone.

http://www.newswise....prostate-cancer

 

Hops is one of the strongest phytoestrogen known, while xanthohumol blocks estrogen too an hops extract might contain 8-Prenylnaringenin which is damn estrogenic.

 

I would stay well away from hops and its extracts....unless you like to grow big boobs (and prostate), of course.

 

 

 

Is there any actual evidence that hops are bad for male fertlity though? Is there even any evidence that small amounts of 8-prenylnaringenin (the strongest beer phytoestrogen) are bad?

 

I've spent weeks drinking IPA beer, and I've spent weeks abstaining from alcohol. I never noticed any difference sexually TBH.

[normalizing]

As said I will stay well away from hops in any amounts, a beer some now and then is all I would consider unlikely to play a significant role.

 

By the way beer wasn't originally intended to contain hops, it is a much later add which has to do with religion since it suppress sexual desire.

 

I can't see any reason why a sleeping aid should contain hops in any form or amount, to prevent spontaneous nocturnal hard ons to wake one up maybe?  

 

its true beer unlike wine doesnt excite one sexually, at least not as much considering alcohol usually does it, but in my case drinking high hop levels of beer still gave me overnight erections and sexual desire. what about asian population consuming high amounts of soy which is as or even more estrogenic and should basically completely inhibit their sex drive?? something doesnt click here....

[aconita]

Beer contain very little hops, only an everyday habit could effect hormones and yes, at certain amounts it does.

 

Alcohol isn't good for sex, any kind of alcohol, if only for that matter it tends to have one driving faster too.... but not better.

 

High estrogens doesn't necessarily mean no sex drive, it is a bit more complicate than that but anyway lets say it doesn't help.

[Young Paul]

its true beer unlike wine doesnt excite one sexually, at least not as much considering alcohol usually does it, but in my case drinking high hop levels of beer still gave me overnight erections and sexual desire. what about asian population consuming high amounts of soy which is as or even more estrogenic and should basically completely inhibit their sex drive?? something doesnt click here....

 

asians seem to have tiny codgers, and look feminine, never seen a chinese/asian with a hairy chest and a manly jaw, except sumo wrestlers (and even they have man boobs haha)

My sleeping aid has 80 mg of Hops extract, so for 3-4 tablets it has 240-320mg of Hops extract. Do you reckon it's harmful?

 

you will go into a very deep sleep and wake up with a clitoris

 

jokes aside, I would run a mile from hops

Edited by Young Paul, 16 July 2023 - 09:35 AM.