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A good article about methylation, depression, pathways.

Started by MrHappy , Jan 05 2012 07:15 AM
dna methylation depression

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3 replies to this topic

#1 MrHappy

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Posted 05 January 2012 - 07:15 AM


http://www.enzymestu...methylation.htm

A well-written article, explaining various pathways, dietary requirements and differences in effectiveness of some drugs and supplements in different groups of people - eg. Why some people have bad reactions to SSRIs, why SAMe is effective for some and not others and a lot more.

Worth reading, especially if you are new to supplements.
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#2 LeonardElijah

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Posted 15 January 2012 - 07:12 PM

Thanks.

They need to stop talking about folic acid and start talking about methylfolate.

I respond to methylfolate.

Required to produce SAMe:

TMG
B6 in the form of P5P
Methylfolate
MethylB12

I can't speak to the minerals such as zinc because I never responded to those when messing around with methylation.

I qualify as an "overmethylator" when I add in the TMG. Sometimes I'm not stressed ENOUGH. The conversion is Choline (4 methyl groups) -> TMG (three methyl groups) -> DMG (two methyl groups). By dropping TMG, you are relying on choline. It's not like this is the biggest issue ever, but sometimes I want a little more stress incentive to get my stuff done.

Edited by LeonardElijah, 15 January 2012 - 07:13 PM.

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#3 Thorsten3

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Posted 15 January 2012 - 10:56 PM

http://www.enzymestu...methylation.htm

A well-written article, explaining various pathways, dietary requirements and differences in effectiveness of some drugs and supplements in different groups of people - eg. Why some people have bad reactions to SSRIs, why SAMe is effective for some and not others and a lot more.

Worth reading, especially if you are new to supplements.


Good read thanks

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#4 WillHen

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Posted 27 May 2014 - 01:27 PM

Thank you MrHappy...great information
Back to Brain Health



Also tagged with one or more of these keywords: dna, methylation, depression

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