Hi,
Any supplements to activate NQO1 without downregulating PARP?
I get that inhibiting PARP is effective in raising NAD+ levels and that PARP is over expressed in the aged.
However, I believe that PARP is a response to large oxidation damage/ DNA damages, and is important not to decrease, especially for younger person like me.
Anyone knows of ways to activate NQO1 that doesn’t involve inhibiting PARP?